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二世年鑑
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Innovations for Next-Generation Antibody-Drug Conjugates
Antibody-drug conjugates (ADCs) stand at the verge of a transformation. Scores of clinical programs have yielded only a few regulatory approvals, but a wave of technological innovation now empowers us to overcome past technical challenges. This volume focuses on the next generation of ADCs and the innovations that will enable them. The book inspires the future by integrating the field’s history with novel strategies and cutting-edge technologies. While the book primarily addresses ADCs for solid tumors, the last chapter explores the emerging interest in using ADCs to treat other diseases. The therapeutic rationale of ADCs is strong: to direct small molecules to the desired site of action (...
Photochemistry Vol 8
Annotation. The breadth of scientific and technological interests in the general topic of photochemistry is truly enormous and includes, for example, such diverse areas as microelectronics, atmospheric chemistry, organic synthesis, non-conventional photoimaging, photosynthesis, solar energy conversion, polymer technologies, and spectroscopy. This Specialist Periodical Report on Photochemistry aims to provide an annual review of photo-induced processes that have relevance to the above wide-ranging academic and commercial disciplines, and interests in chemistry, physics, biology and technology. In order to provide easy access to this vast and varied literature, each volume of Photochemistry co...
Ancient Ryukyu
Who are the people of the Ryukyu Islands? How could they survive and prosper on small, isolated islands? How did the independent Ryukyu Kingdom become a major player in East Asian medieval trade? Ancient Ryukyu explores 30,000 years of human occupation in the Ryukyu Islands, from the earliest human presence in the region up to A.D. 1609 and the emergence of the Ryukyu Kingdom. It focuses on the unique geopolitical position of the islands, their environment, and the many human communities whose historical activities can be discerned. Drawing on the impressive work of dozens of local archaeologists who have brought the islands’ early history to life, Richard Pearson describes explorers and s...
