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Where Biology Ends and Bias Begins
A geneticist and internationally recognized anti-racism educator provides a powerful, science-based rebuttal to common fallacies about human difference. Well-meaning physicians, parents, and even scientists today often spread misinformation about what biology can and can’t tell us about our bodies, minds, and identities. In this accessible, myth-busting book, geneticist Shoumita Dasgupta draws on the latest science to correct common misconceptions about how much of our social identities are actually based in genetics. Dasgupta weaves together history, current affairs, and cutting-edge science to break down how genetic concepts are misused and how we can approach scientific evidence in a socially responsible way. With a unifying and intersectional approach disentangling biology from bigotry, the book moves beyond race and gender to incorporate categories like sexual orientation, disability, and class. Where Biology Ends and Bias Begins is an invaluable, empowering resource for biologists, geneticists, science educators, and anyone working against bias in their community.
Global Perspectives on Precision Medicine
This book presents the promises of Precision Medicine (PM) and the challenges of its implementation in daily clinical routine, while addressing the anticipated ethical and social implications. It is the first book that critically analyzes the potential and the dilemmas relevant to genomics and precision medicine from healthcare, public health and global perspectives. The nine chapters presented in this book elaborate on pharmacogenomics' crucial role in maximizing the potential benefits and minimizing medication's potential risks in groups of people, especially in cancer treatment and other health conditions. Infectious and non-communicable diseases (NCDs) are also discussed in this book by identifying challenges and ways to overcome them. Essential concepts are addressed, such as health-related benefits and harm to individuals and the broader community, including threats to individual privacy and autonomy, which warrant just distribution of scarce resources. The book also identifies and addresses the lack of competency in the healthcare workforce in the era of PM and discusses the path to laying the ethical foundation for the implementation of PM in healthcare organizations.
Genetics and Genomics in Medicine
Genetics and Genomics in Medicine is a new textbook written for undergraduate students, graduate students, and medical researchers that explains the science behind the uses of genetics and genomics in medicine today. Rather than focusing narrowly on rare inherited and chromosomal disorders, it is a comprehensive and integrated account of how geneti
Examination of the Nitrosative Stress Response in Histoplasma Capsulatum
Histoplasma capsulatum is a dimorphic pathogenic fungus. In the soil, H. capsulatum grows in a mycelial form. When soil containing H. capsulatum is disturbed, mycelial fragments or conidia (vegetative-spores) become aerosolized. Once inhaled by a mammalian host, mycelial fragments and/or conidia convert into a yeast-like form. H. capsulatum yeast escape innate immune defenses and colonize host macrophages during infection. After the onset of adaptive immunity, activated macrophages produce the antimicrobial effector nitric oxide ( * NO) to restrict H. capsulatum replication. However, despite exposure to reactive nitrogen species (RNS), H. capsulatum is able to establish persistent infections...
Models of Cellular Regulation
This book illustrates the mechanisms and models linking the realms of molecular interactions and biological processes or functions. It addresses the need of mathematical modelers to learn how to formulate models of cellular processes and to understand how quantitative modeling can help sort through the complexities of molecular regulatory networks.
Sweetness in the Blood
A bold new indictment of the racialization of science Decades of data cannot be ignored: African American adults are far more likely to develop Type 2 diabetes than white adults. But has science gone so far in racializing diabetes as to undermine the search for solutions? In a rousing indictment of the idea that notions of biological race should drive scientific inquiry, Sweetness in the Blood provides an ethnographic picture of biotechnology’s framings of Type 2 diabetes risk and race and, importantly, offers a critical examination of the assumptions behind the recruitment of African American and African-descent populations for Type 2 diabetes research. James Doucet-Battle begins with a h...
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