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In recent years, there has been a surge of interest in developing nanomedicine-based approaches for cancer treatment. This is largely due to the unique properties of nanoparticles, such as their small size and ability to target specific cells or tissues, which make them ideal candidates for delivering drugs or imaging agents to cancer cells. Furthermore, the development of nanomedicine-based cancer therapies has the potential to significantly improve treatment efficacy and reduce side effects compared to traditional chemotherapy or radiation However, there are still challenges that need to be overcome in the development of cancer nanomedicines, including issues related to toxicity, stability, scalability, and regulatory approval. Efforts are underway to address these challenges through rigorous testing and research, as well as collaboration between academia, industry, and regulatory agencies. Overall, the field of cancer nanomedicine holds great promise for advancing cancer treatment and improving patient outcomes. As research in the field continues, it is expected that new and innovative nanomedicine-based approaches will emerge, paving the way for more effective cancer
Targeted Cancer Imaging: Design and Synthesis of Nanoplatforms based on Tumour Biology reviews and categorizes imaging and targeting approaches according to cancer type, highlighting new and safe approaches that involve membrane-coated nanoparticles, tumor cell-derived extracellular vesicles, circulating tumor cells, cell-free DNAs, and cancer stem cells, all with the goal of pointing the way to developing precise targeting and multifunctional nanotechnology-based imaging probes in the future. This book is highly multidisciplinary, bridging the knowledge gap between tumor biology, nanotechnology, and diagnostic imaging, and thus making it suitable for researchers ranging from oncology to bio...
Leading experts summarize and synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to anticancer drugs, and suggest new approaches to preventing and overcoming it. The authors review physiological resistance based upon tumor architecture, cellular resistance based on drug transport, epigenetic changes that neutralize or bypass drug cytotoxicity, and genetic changes that alter drug target molecules by decreasing or eliminating drug binding and efficacy. Highlights include new insights into resistance to antiangiogenic therapies, oncogenes and tumor suppressor genes in therapeutic resistance, cancer stem cells, and the development of more effective therapies. There are also new findings on tumor immune escape mechanisms, gene amplification in drug resistance, the molecular determinants of multidrug resistance, and resistance to taxanes and Herceptin.
This book aims to give readers a basic understanding of commonly used additive manufacturing techniques as well as the tools to fully utilise the strengths of additive manufacturing through the modelling and design phase all the way through to post processing. Guidelines for 3D-printed biomedical implants are also provided. Current biomedical applications of 3D printing are discussed, including indirect applications in the rapid manufacture of prototype tooling and direct applications in the orthopaedics, cardiovascular, drug delivery, ear-nose-throat, and tissue engineering fields. Polymer-Based Additive Manufacturing: Biomedical Applications is an ideal resource for students, researchers, and those working in industry seeking to better understand the medical applications of additive manufacturing.
Celebrating the work of renowned mathematician Jerome A. Goldstein, this reference compiles original research on the theory and application of evolution equations to stochastics, physics, engineering, biology, and finance. The text explores a wide range of topics in linear and nonlinear semigroup theory, operator theory, functional analysis, and li
Electrospun Polymers and Composites: Ultrafine Materials, High Performance Fibres and Wearables reviews the latest technological developments and innovations in electrospun polymers and composites, highlighting the multifunctionality of these ultrafine materials as high performance fibers. The book's chapters investigate a wide range of different electrospinning applications, including drug delivery, tissue scaffolding, fiber reinforcement and nanofiltration, with a particular focus on shape memory effect and the wearable characteristics of electrospun polymers and composites. This will be a valuable reference resource for research and for industrial communities working in the field of electrospinning. - Covers two important material systems in electrospun materials, including electrospun polymers and composites - Emphasizes areas in shape memory effect and wearable features of electrospun polymers and composites - Presents a multidisciplinary work that will attract a wide spectrum of readers in chemical engineering, biomedical engineering, chemistry, pharmacy, environmental science, materials science and engineering, as well as mechanical and electrical engineering
A mother and son recall a childhood of limited resources, tensions, and religiously advocated child abuse during the politically tempestuous '50s and '60s in Iran. Photos.