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Heredity under the Microscope
By focusing on chromosomes, Heredity under the Microscope offers a new history of postwar human genetics. Today chromosomes are understood as macromolecular assemblies and are analyzed with a variety of molecular techniques. Yet for much of the twentieth century, researchers studied chromosomes by looking through a microscope. Unlike any other technique, chromosome analysis offered a direct glimpse of the complete human genome, opening up seemingly endless possibilities for observation and intervention. Critics, however, countered that visual evidence was not enough and pointed to the need to understand the molecular mechanisms. Telling this history in full for the first time, Soraya de Chad...
Models
Now that '3-D models’ are so often digital displays on flat screens, it is timely to look back at the solid models that were once the third dimension of science. This book is about wooden ships and plastic molecules, wax bodies and a perspex economy, monuments in cork and mathematics in plaster, casts of diseases, habitat dioramas, and extinct monsters rebuilt in bricks and mortar. These remarkable artefacts were fixtures of laboratories and lecture halls, studios and workshops, dockyards and museums. Considering such objects together for the first time, this interdisciplinary volume demonstrates how, in research as well as in teaching, 3-D models played major roles in making knowledge. Accessible and original chapters by leading scholars highlight the special properties of models, explore the interplay between representation in two dimensions and three, and investigate the shift to modelling with computers. The book is fascinating reading for anyone interested in the sciences, medicine, and technology, and in collections and museums.
Molecularizing Biology and Medicine
The contributors present a coherent set of case studies of practices, technologies and strategies aimed at the isolation, investigation, manipulation, production, and uses of molecules including vitamins, hormones, blood products, antibiotics, and vaccines. These case studies examine how processes of molecularization were set in motion in the inter-war period, how they were used as a resource in the biomedical 'mobilization' of World War II, and how new alliances and strategies created as part of the war effort played a central role in the reorganisation of biomedicine in the post-war period.
Designs for Life
An important study on the making of molecular biology and its cultural contexts.
A History of Molecular Biology
Every day it seems the media focus on yet another new development in biology--gene therapy, the human genome project, the creation of new varieties of animals and plants through genetic engineering. These possibilities have all emanated from molecular biology. A History of Molecular Biology is a complete but compact account for a general readership of the history of this revolution. Michel Morange, himself a molecular biologist, takes us from the turn-of-the-century convergence of molecular biology's two progenitors, genetics and biochemistry, to the perfection of gene splicing and cloning techniques in the 1980s. Drawing on the important work of American, English, and French historians of s...
The Disunity of Science
Is science unified or disunified? Over the last century, the question has raised the interest (and hackles) of scientists, philosophers, historians, and sociologists of science, for at stake is how science and society fit together. Recent years have seen a turn largely against the rhetoric of unity, ranging from the please of condensed matter physicists for disciplinary autonomy all the way to discussions in the humanities and social sciences that involve local history, feminism, multiculturalism, postmodernism, scientific relativism and realism, and social constructivism. Many of these varied aspects of the debate over the disunity of science are reflected in this volume, which brings toget...
The Educated Eye
The creation and processing of visual representations in the life sciences is a critical but often overlooked aspect of scientific pedagogy. The Educated Eye follows the nineteenth-century embrace of the visible in new spectatoria, or demonstration halls, through the twentieth-century cinematic explorations of microscopic realms and simulations of surgery in virtual reality. With essays on Doc Edgerton's stroboscopic techniques that froze time and Eames's visualization of scale in Powers of Ten, among others, contributors ask how we are taught to see the unseen.
Science on Stage
Behind today's headlines stands an unobtrusive army of science advisors—panels of scientific, medical, and engineering experts evaluate the safety of the food we eat, the drugs we take, and the cars we drive. This book studies, theoretically and empirically, the social process through which the credibility of expert advice is produced, challenged, and sustained.
On Beyond Living
What do biologists study when they study "life" today? Drawing on tools from rhetoric and poststructuralist theory, the author argues that the ascent of molecular biology, with its emphasis on molecules such as DNA rather than organisms, was enabled by crucial rhetorical "softwares." Metaphors such as the genetic "code" made possible a transformation of the very concept of life, a transformation that often casts organisms as information systems. With careful readings of key texts from the history of molecular biology—such as those of Erwin Schrödinger, George Gamow, Jacques Monod, and François Jacob—the author maps out the complex relations between the practices of rhetoric and the tec...
