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Designs for Life
An important study on the making of molecular biology and its cultural contexts.
Heredity under the Microscope
By focusing on chromosomes, Heredity under the Microscope offers a new history of postwar human genetics. Today chromosomes are understood as macromolecular assemblies and are analyzed with a variety of molecular techniques. Yet for much of the twentieth century, researchers studied chromosomes by looking through a microscope. Unlike any other technique, chromosome analysis offered a direct glimpse of the complete human genome, opening up seemingly endless possibilities for observation and intervention. Critics, however, countered that visual evidence was not enough and pointed to the need to understand the molecular mechanisms. Telling this history in full for the first time, Soraya de Chad...
Models
Now that '3-D models’ are so often digital displays on flat screens, it is timely to look back at the solid models that were once the third dimension of science. This book is about wooden ships and plastic molecules, wax bodies and a perspex economy, monuments in cork and mathematics in plaster, casts of diseases, habitat dioramas, and extinct monsters rebuilt in bricks and mortar. These remarkable artefacts were fixtures of laboratories and lecture halls, studios and workshops, dockyards and museums. Considering such objects together for the first time, this interdisciplinary volume demonstrates how, in research as well as in teaching, 3-D models played major roles in making knowledge. Accessible and original chapters by leading scholars highlight the special properties of models, explore the interplay between representation in two dimensions and three, and investigate the shift to modelling with computers. The book is fascinating reading for anyone interested in the sciences, medicine, and technology, and in collections and museums.
Molecularizing Biology and Medicine
The contributors present a coherent set of case studies of practices, technologies and strategies aimed at the isolation, investigation, manipulation, production, and uses of molecules including vitamins, hormones, blood products, antibiotics, and vaccines. These case studies examine how processes of molecularization were set in motion in the inter-war period, how they were used as a resource in the biomedical 'mobilization' of World War II, and how new alliances and strategies created as part of the war effort played a central role in the reorganisation of biomedicine in the post-war period.
A History of Molecular Biology
Every day it seems the media focus on yet another new development in biology--gene therapy, the human genome project, the creation of new varieties of animals and plants through genetic engineering. These possibilities have all emanated from molecular biology. A History of Molecular Biology is a complete but compact account for a general readership of the history of this revolution. Michel Morange, himself a molecular biologist, takes us from the turn-of-the-century convergence of molecular biology's two progenitors, genetics and biochemistry, to the perfection of gene splicing and cloning techniques in the 1980s. Drawing on the important work of American, English, and French historians of s...
The Educated Eye
The creation and processing of visual representations in the life sciences is a critical but often overlooked aspect of scientific pedagogy. The Educated Eye follows the nineteenth-century embrace of the visible in new spectatoria, or demonstration halls, through the twentieth-century cinematic explorations of microscopic realms and simulations of surgery in virtual reality. With essays on Doc Edgerton's stroboscopic techniques that froze time and Eames's visualization of scale in Powers of Ten, among others, contributors ask how we are taught to see the unseen.
Collecting Experiments
Databases have revolutionized nearly every aspect of our lives. Information of all sorts is being collected on a massive scale, from Google to Facebook and well beyond. But as the amount of information in databases explodes, we are forced to reassess our ideas about what knowledge is, how it is produced, to whom it belongs, and who can be credited for producing it. Every scientist working today draws on databases to produce scientific knowledge. Databases have become more common than microscopes, voltmeters, and test tubes, and the increasing amount of data has led to major changes in research practices and profound reflections on the proper professional roles of data producers, collectors, ...
The Historiography of Contemporary Science and Technology
More than ninety percent of all scientific history has been made during the last half century. So far, however, only a fraction of historical scholarship has dealt with this period. Merely a decade ago, most scientific historians considered recent science - the scientific culture created, lived and remembered by contemporary scientists - an area of study best left to the historical actors themselves.
The Local Configuration of New Research Fields
This new Yearbook addresses the question of how policy, place, and organization are made to matter for a new research field to emerge. Bringing together leading historians, sociologists, and organizational researchers on science and technology, the volume answers this question by offering in-depth case studies and comparative perspectives on multiple research fields in their nascent stage, including molecular biology and materials science, nanotechnology, and synthetic biology. The Yearbook brings to bear the lessons of constructivist ethnography and the “practice turn” in Science and Technology Studies (STS) more broadly on the qualitative, comparative, and critical inquiry of new research fields. In doing so, it offers unprecedented insights into the complex interplay of national research policies, regional clusters, particular research institutions, and novel research practices in and for any emerging field of (techno-)science. It systematically investigates national and regional differences, including the variable mobilization of such differences, and probes them for organizational topicality and policy relevance.
