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Lost Restaurants of Philadelphia
Culinary Memories from Philidelphia's Past...Beyond the Cheesesteak Long before Philadelphia's food scene was splashed on covers of Bon Appetit and local establishments garnered accolades like America's best restaurant, culinary pioneers set the city's restaurant industry ablaze. Frenchman Georges Perrier brought the city the highest, most-respected opulence, Le Bec-Fin, for 40 years running. The ultimate seafood institute, Old Original Bookbinder's, held the title of the world's largest lobster tank and prepared impeccable oyster Rockefeller. Steve Poses changed the culinary game with the Frog that captivated palates with the infusion of international flavors. The nation's very first automat, Horn & Hardart's, consistently delivered near-perfect comfort food classics via vending machine. Amy Strauss revisits celebrated spaces, unforgettable personalities and must-have recipes that made Philadelphia's historic restaurants remembered for their delicious moments in time.
HIV-Host Interactions
HIV remains the major global health threat, and neither vaccine nor cure is available. Increasing our knowledge on HIV infection will help overcome the challenge of HIV/AIDS. This book covers several aspects of HIV-host interactions in vitro and in vivo. The first section covers the interaction between cellular components and HIV proteins, Integrase, Tat, and Nef. It also discusses the clinical relevance of HIV superinfection. The next two chapters focus on the role of innate immunity including dendritic cells and defensins in HIV infection followed by the section on the impact of host factors on HIV pathogenesis. The section of co-infection includes the impact of Human herpesvirus 6 and Trichomonas vaginalis on HIV infection. The final section focuses on generation of HIV molecular clones that can be used in macaques and the potential use of cotton rats for HIV studies.
Through Carmela's Eyes
This is the story of a young girl, an Italian immigrant, who was brought to America in hopes of a better life. Times were hard and her parents were forced to take her out of school, at age twelve and send her to work in one of the woolen mills in Lawrence Massachusetts. While there, she endured a devastating accident that would forever alter her life and that of her family. The repercussions would extend far beyond anything that could be imagined. Carmela Teoli, after spending seven months in a hospital, would go on to testify to a Congressional Committee about the conditions under which she, and the other children, had been forced to work. Her words had the power to influence many people in...
Mitochondrial Dynamics in Cardiovascular Medicine
This text covers the basic principles of mitochondrial dynamics in cardiovascular medicine, with particular emphasis on their functional roles in physiology and disease. The book will include articles pertaining to mitochondrial fitness on a global basis, providing therefore an update on the progress made in several aspects in the field. Thus, it will assist scientists and clinicians alike in furthering basic and translational research. Organized in sections focusing on: basic science, mitochondrial dysfunction in cardiac disorders, in vascular disorders, in metabolic disorders, in kidney disease, therapeutic challenges and options, this essential volume fills imperative gaps in understanding and potentially treating several cardiovascular disorders.
Letcher County
Since 1795, when Peter Whitaker built the first known settlement on what is now Linefork Creek, Letcher Countians have demonstrated the perseverance and fortitude for which Appalachian people are known. The majesty of Pine Mountain in the south of the county or the rare beauty of old-growth forests that became Lilley Cornett Woods must have brought Daniel Boone to seek a paradise in "Kanta-ke." Whitesburg and Letcher County have seen their resources of timber, oil, and coal bring growth, as well as decline. With the rise of the coal industry before World War I came a steady flow of Eastern European immigrants who contributed a new and exciting perspective on life, business, and art. It was Italian stonemason John Palumbo Sr. who led other Italians to Whitesburg because the beauty of it reminded him of his home in the Campania region of Southern Italy. The churches, homes, and buildings they established stand in homage to their energy and skill.
Melanin
The word melanin refers to dark natural pigments produced by the oxidative degradation of tyrosine, catalyzed by tyrosinase, and polymerized into insoluble granular substance. The main function of melanin is to protect from harmful agents, primarily UV radiation, but also from oxidation, heavy metals, etc. In this volume, chapters deal with production of melanin in human oral mucosa (Liviu et al.), the regulation of melanin action (Cecile et al.), production and potential technological application of fungal melanins (Pombiero-Sponchiado et al.) and an innovative method for measuring melanin in various samples (Zdybel et al.). In conclusion, this volume presents various biological and industrial aspects of melanin production, uses and analysis.
Exploring Gender at Work
A timely work that reviews the phenomenon of gender and its many manifestations of equality. Well-suited for increasing awareness and justice in academic and professional environments, this collective work addresses long-standing and ongoing social problems such as discrimination, stereotyping, prejudice, as well as a plethora of societal and industry influences that sustain the trend of gender imbalance. Aiming to span a broad scope in time, backgrounds and implementation, this book presents a wide variety of topics, including a historical overview, contemporary gender-based Issues, gender approaches across the disciplines, and cultural influences. The reader is guaranteed to confront existing biases when digesting topics related to gender communication differences, stereotypes, tensions and resistances, assigned social roles, transgenderism, non-binary identities, tension fields between equality and equity, relational aggression, and more. A critical underlying aim of this book is to contribute constructively and progressively to the dialogue on the definition of gender, thus addressing an ongoing challenge for policy makers, organizational leaders, and scholars.
Advances in Structural Biology
In keeping with the broad objectives set for the serial publication of Advances in Structural Biology, Volume 6 contains exhaustive articles from experts in diverse areas of biomedical research. The common thread among the various articles is their relevance to the applications of cell biology to human health.
