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The recent revolution in molecular biology offers exciting new opportunities for targeted radionuclide therapy. This up-to-date, comprehensive book, written by world-renowned experts, discusses the basic principles of radionuclide therapy, explores in detail the available treatments, explains the regulatory requirements, and examines likely future developments. The full range of clinical applications is considered, including thyroid cancer, hematological malignancies, brain tumors, liver cancer, bone and joint disease, and neuroendocrine tumors. The combination of theoretical background and practical information will provide the reader with all the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Careful attention is also paid to the role of the therapeutic nuclear physician in coordinating a diverse multidisciplinary team, which is central to the safe provision of treatment.
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
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Radiophannaceutical research has recently undergone a major change in direction. In past years it has been concerned mainly with the development of perfusion tracers, the biodistribution of which reflect the regional blood flow to areas of major organs such as the heart and brain. However, a major new direction of interest now lies in the development of receptor-binding radio-tracers which can be used to perform in-vivo characterisation of diseased tissues and it is likely that much of the future research in this field will follow this direction. The difficulties in developing such tracers are considerable. The researcher must first identify a promising target for radiopharmaceutical develop...
Supplements 1-14 have Authors sections only; supplements 15-24 include an additional section: Parasite-subject catalogue.
Due to the increasing pressure of a globalized economy and under the effects of a changing climate, biological invasions have become a frequent feature of marine and freshwater environments. Global fisheries and aquaculture are therefore required to adjust to these changes, with the dual aim of reducing the negative ecological consequences caused by these species and making the most of the advantages they might bring. Here, capitalizing on a wide spectrum of management actions which can be implemented to control and/or adapt to aquatic invasions, nine measures are presented; they can be grouped under environmental, social or socioeconomic strategies, exploring their potential, main challenge...