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Takes the reader step-by-step from the structures of simple molecules, such as methane, to the basic shapes of biologically important macromolecules, such as proteins and nucleic acids. Deals with the concept of chirality, which is often overlooked by many texts. Chirality is approached by firstly explaining the stereochemistry of compounds with one stereogenic centre, then dealing with compounds having two or more stereogenic centres before focusing on compounds possessing axes of chirality. The importance of stereochemistry in a wide variety of transformations (for example addition reactions, eliminations, and cycloadditions), is discussed. The final chapters describe the application of stereocontrol in asymmetric synthesis, indicating the use of chiral auxiliaries and chiral catalysts in modern chemistry.
First multi-year cumulation covers six years: 1965-70.
A Political, Social, and Cultural History is a comprehensive and balanced history, covering the political, military, social, cultural, and economic history of ancient Greece from the Bronze Age to the Hellenistic Era.
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This volume represents the proceedings of a NATO Advanced Studies Instituteheld near Barga (Italy), July 11-23, 1988, involving over 90 participants from more than twelve countries of Europe, North America and elsewhere. It was not our intention at this meeting to present a complete up-to-the-minute review of current research in enzyme catalysis but t·ather, in accord wi th the intended spiri t of NATO ASis, to gi ve an opportunity for advanced students and researchers in a wide variety of disciplines to meet tagether and study the problern from different points of view. Hence the lectures cover topics rauging from the purely theoretical aspects of chemical reaction kinetics in condensed ma...
The story of the ancient Greeks is one of the most improbable success stories in world history. A small group of people inhabiting a country poor in resources and divided into hundreds of quarreling states created one of the most remarkable civilizations ever. Comprehensive and balanced, A Brief History of Ancient Greece: Politics, Society, and Culture, Second Edition is a shorter version of the authors' highly successful Ancient Greece: A Political, Social, and Cultural History, Second Edition (OUP, 2008). Four leading authorities on the classical world offer a lively and up-to-date account of Greek civilization and history in all its complexity and variety, covering the entire period from ...
Advances in Asymmetric Synthesis
The use of natural catalysts - enzymes - for the transformation of non-natural is not at all new: they have been used for more man-made organic compounds than one hundred years, employed either as whole cells, cell organelles or isolated enzymes [1]. Certainly, the object of most of the early research was totally different from that of the present day. Thus the elucidation of biochemical pathways and enzyme mechanisms was in the foreground of the reasearch some decades ago. It was mainly during the 1980s that the enormous potential of applying natural catalysts to transform non-natural organic compounds was recognized. What started as a trend in the late 1970s could almost be called a fashio...