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Pediatric and Adolescent Osteosarcoma
  • Language: en
  • Pages: 591

Pediatric and Adolescent Osteosarcoma

Pediatric and Adolescent Osteosarcoma provides a historical review of the nature of osteosarcoma and the conflict that accompanied the introduction of adjuvant therapy for osteosarcoma culminating in accepted and prevailing methods of current therapy. It outlines concepts in Epidemiology and Etiology, and provides chapters on pathology and radiologic characteristics of osteosarcoma, surgical therapy tailored specifically for treatment of primary tumors in pediatric/adolescent age group, treatment of pulmonary and extra pulmonary metastases and complications, as well as the role of radiation therapy. The volume concludes with a review of differences and similarities in the management of osteo...

Sarcomas of Bone and Soft Tissues in Children and Adolescents
  • Language: en
  • Pages: 181

Sarcomas of Bone and Soft Tissues in Children and Adolescents

This book is a comprehensive and up-to-date compendium on all aspects of sarcomas of bone and soft tissues in childhood and adolescence. After introductory chapters on the history, epidemiology, and biology of pediatric sarcomas, treatment considerations are extensively reviewed, with emphasis on the use of risk-adjusted treatment approaches. The pathology and biology of this diverse group of tumors are extensively reviewed. Promising new treatment approaches are discussed, and strategies for the development of new agents are appraised. The major common pediatric sarcomas, including osteosarcoma, Ewing sarcoma, rhabdomyosarcoma and non-rhabdomyosarcoma soft tissue sarcoma, are covered in detail. The authors are internationally recognized experts who offer a largely evidence-based consensus on etiology, biology, and treatment. This handbook has far-reaching applicability to the clinical diagnosis and management of childhood and adolescent sarcomas and will prove invaluable to specialists, generalists, and trainees alike.

Journal of the National Cancer Institute
  • Language: en
  • Pages: 556

Journal of the National Cancer Institute

  • Type: Book
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  • Published: 2010
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  • Publisher: Unknown

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Late Treatment Effects and Cancer Survivor Care in the Young
  • Language: en
  • Pages: 419

Late Treatment Effects and Cancer Survivor Care in the Young

This comprehensive guide describes the aftercare that is appropriate in young cancer patients and discusses in detail the risk and detection of treatment sequelae. It explains the impacts on body and mind of both the disease itself and the different risk-adapted cancer treatments currently in use. Clear guidance is provided on diagnosis and management of the principal treatment-related toxicities in different organs and organ systems and for a wide variety of tumor types. In addition, the role of genetic polymorphisms in the development of adverse therapy-related outcomes is explored, and advice offered on genetic counselling. As the number of long-term survivors of childhood cancer and of cancer in young adults continues to grow, so issues surrounding potential sequelae, second malignancies, and quality of life are becoming ever more important. All practitioners involved in the care of young cancer patients will find this book to be a helpful source of up-to-date information and assistance.

Late Sequelae in Oncology
  • Language: en
  • Pages: 436

Late Sequelae in Oncology

Increasing survival figures and the use of more intense combined treatment regimens in modern oncology have raised the problem of late therapeutic sequelae in long-term survivors after cancer. Recent scientific approaches to late sequelae concentrate on the evaluation of subclinical changes with sophisticated functional measurements and experimental investigation of the underlying pathophysiological mechanisms. The objective of the book is to bring together these recent clinical and experimental data from different medical disciplines to give an overview of the most relevant problems of late sequelae. In clinical practice the book may help regarding estimation of risks, selection of diagnostic methods, and estimation of the prognosis of late sequelae.

AACR 2022 Proceedings: Part A Online-Only and April 10
  • Language: en
  • Pages: 2287

AACR 2022 Proceedings: Part A Online-Only and April 10

The AACR Annual Meeting is the focal point of the cancer research community, where scientists, clinicians, other health care professionals, survivors, patients, and advocates gather to share the latest advances in cancer science and medicine. From population science and prevention; to cancer biology, translational, and clinical studies; to survivorship and advocacy; the AACR Annual Meeting highlights the work of the best minds in cancer research from institutions all over the world.

Cancer in Children
  • Language: en
  • Pages: 423

Cancer in Children

This work covers the aetiology, symptoms and treatment of cancer in children, featuring contributions from leading experts on the subject. The edition includes several new chapters on future trends in chemotherapy, surgery, pallitive care and myeloid leukaemia.

Current Advances in Osteosarcoma
  • Language: en
  • Pages: 358

Current Advances in Osteosarcoma

  • Type: Book
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  • Published: 2014-06-12
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  • Publisher: Springer

Current Advances in Osteosarcoma edited by Dr. Eugenie S. Kleinerman summarizes molecular and genetic characteristics, new therapeutic ideas, and biological characteristics that have been uncovered in the past 10 years. Osteosarcoma is an aggressive malignant neoplasm and it is also the most common histological form of bone cancer. It accounts for approximately 56% of new bone tumors, making it the most primary malignant bone tumor in children and adolescents. The lungs are the most common site of metastases and once osteosarcoma spreads to the lungs, it is very difficult to treat. To improve the outcome of this disease, the biology of osteosarcoma needs to be better understood. There are numerous investigators around the world who have made seminal discoveries about the important molecular pathways and genetic alterations that contribute to the development and metastases of osteosarcoma. Other investigators have proposed novel therapeutic strategies including some based on the molecular and genetic phenotype of the disease. Current Advances in Osteosarcoma summarizes all of these new discoveries in one singular text, which will help move the field forward.

Oxford Textbook of Cancer in Children
  • Language: en
  • Pages: 313

Oxford Textbook of Cancer in Children

The Oxford Textbook of Cancer in Children is a well-established and highly regarded text providing clear and up-to-date clinical guidance on the optimal management of childhood cancers.

Cancer in Children and Adolescents
  • Language: en
  • Pages: 646

Cancer in Children and Adolescents

Edited by two leading childhood cancer specialists, and with contributions from authoritative experts in the field, this comprehensive reference covers all aspects of major childhood cancers including molecular oncology and translational therapy, pathological evaluation of childhood cancer, surgical management of pediatric tumors, non-hodgkin's lymphoma and lymphoproliferative disorders in children, infant brain tumors, prevention, diagnosis and treatment of infectious complications, pain management, late effects of childhood cancer therapy.