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In radiation oncology as in many other specialties clinical trials are essential to investigate new therapy approaches. Usually, preparation for a prospective clinical trial is extremely time consuming until ethics approval is obtained. To test a new treatment usually many years pass before it can be implemented in the routine care. During that time, already new interventions emerge, new drugs appear on the market, technical & physical innovations are being implemented, novel biology driven concepts are translated into clinical approaches while we are still investigating the ones from years ago. Another problem is associated with molecular diagnostics and the growing amount of tumor specific...
Modern Radiotherapy (RT) plays a key role in the management of Head and Neck Cancer (HNC). More precise delivery techniques, advanced image-guidance, and adaptive treatments characterize modern RT, enabling safer treatments with enhanced therapeutic window. Although patients identify the cure as their most important treatment outcome, complications related to treatment are a recognized problem as follow-up increases among those cured within this oncologic setting. This is particularly relevant for HPV-related oropharyngeal cancer (OPSCC), as these patients are younger, healthier, and more reactive to treatment. Thus, given the longer life expectancy, the jeopardizing impact of side effects on quality of life (QoL) and psychosocial functioning represent a forefront topic for HNC Researchers. De-escalation protocols have been developed recently, and, although not definitive, evidence is growing. This pertains particularly, but not exclusively, to HPV-related OPSCC.
This innovative book teaches object-oriented programming using Squeaka powerful, freely available language that is highly effective for learning object-oriented programming. The book covers the whole process, while focusing on the basics and compelling case studies.Includes a rich description of object-oriented process. Emphasizes historical perspectives. Introduces simple UML.For readers wanting to learn more about object-oriented programming.
Sascha Wilkens analysiert die Eignung endlicher Mischungen von Verteilungen für Zwecke der Optionsbewertung und geht dabei u.a. auch auf wichtige Implikationen für das Risikomanagement ein. Die Mischungsmodelle werden anhand einer Datenbasis aus mehrjährigen Transaktionsdaten von DAX-, DAX-Aktien- und Euro-Bund-Future-Optionen empirisch untersucht.
This package contains a book and CD of music. It explores the interactive relationship between dance and the other arts including visual, musical and dramatic and literary. Each chapter contains improvisational exercises for gaining perspective and understanding the commonalities across the arts.
Komplett überarbeitet und erweitert liegt jetzt die 7. Auflage der „Strahlentherapie und Radioonkologie aus interdisziplinärer Sicht“ vor, die den immer schneller wachsenden medizinischem Fortschritt in der interdisziplinären Onkologie und der Radioonkologie berücksichtigt. Dieses Lehrbuch ist besonders geeignet zur Weiterbildung im Fachgebiet Strahlentherapie, für Studierende sowie ärztliche Weiterbildungsassistenten/innen und Fachärzte/innen auf dem Gebiet der Strahlentherapie. Es werden aber auch andere Berufsgruppen, wie in der Strahlentherapie tätige MTRAs, MFAs, Medizinphysikexperten/innen oder Pflegepersonal angesprochen – und natürlich interessierte ärztliche Kollegen...
Das Black/Scholes-Modell ist das weltweit dominierende Modell zur Bewertung finanzwirtschaftlicher Optionen. Andreas Merk überprüft zentrale Annahmen des Modells und wertet Preisabweichungen aus, die sich zwischen dem Modell und den Transaktionsdaten für die DAX-Option ergeben.