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Handbook of Stereotactic and Functional Neurosurgery
This volume offers a comprehensive discussion of the stereotactic frames, frameless systems, and radiosurgical procedures utilized in the treatment and control of movement and neurological disorders, Parkinson's disease, chronic pain, spasticity, tumours, epilepsy, and arteriovenous malformations.
Molecular Basis of Aging
Using a new, integrative approach, Molecular Basis of Aging describes the aging phenomenon within mammalian organisms from the perspective of changes in information storage and coordination between hierarchical orders of structure. This unique approach provides the reader with a thorough insight into the evolution of molecular, cellular, tissue, and organ systems and processes in mammals. This informative volume contains up-to-date reviews of:
Acute Stroke
As the third leading cause of death in the United States, stroke accounts for one in every fifteen deaths and is the major cause of disability in the country. Compiled by a renowned editorial team, this reference bridges the gap between basic science and patient care protocols, and collects 43 expertly written chapters that range from laboratory-ba
Handbook of Dystonia
As many as 250,000 people in the United States have dystonia, making it the third most common movement disorder following essential tremor and Parkinson's disease. This authoritative reader-friendly resource provides a wide-ranging overview of the latest research and developments regarding the pathogenesis, evaluation, and management of the disease
Surgical Management of Movement Disorders
A thorough review of the surgical procedures and technologies currently available for the treatment of various movement disorders, this guide illustrates strategies for the management of conditions such as Parkinson's disease, essential tremor, dystonia, Tourette's syndrome, hemifacial spasm, and cerebral palsy-emphasizing surgical indications and
Women’s Health and Menopause
The population structure in the world is rapidly changing, to the extent that in 75 years we will face a tripling of the elderly population. Although women are favored in terms of life expectancy, they also live with a longer period of disability (approximately twice that of aging men), as well as with the enemies of all the elderly, cardiovascular disease, cancer, and dementia. Menopause is the endocrine event that overlaps with aging, potentially worsening both the quality of life and the risks of disease in women.While the effect of hormone replacement therapy (HRT) on menopausal symptoms is generally viewed as rapid and consistent, and is thereby accepted by the scientific community, its relationship to the other aforementioned chronic conditions associated with menopause is considered variable and controversial.In analyzing these complex issues, this volume yields new and significant insights into both the study of menopause-related disorders and their treatment, by illustrating the most recent information on mechanisms of actions of new estrogen receptors and on the use of sophisticated techniques of statistical analysis for population-based studies.
Enzymes in the Valorization of Waste
Enzymes in the Valorization of Waste: Next-Gen Technological Advances for Sustainable Development of Enzyme-based Biorefinery focusses on key enzymes which are involved in the development of integrated biorefinery. It highlights the modern next-gen technologies for promoting the application of sustainable and greener enzymatic steps at industrial scale for the development of futuristic and self-sustainable "consolidated/integrated biorefinery/enzyme-based biorefinery." It also deals with technological advancement for improvement of enzyme yield or specificity, conversion capability, such as protein and metabolic engineering and advances in next generation technologies, and so forth. Features...
Political Friendship and the Good Life
The main subject of this book is the rather fascinating link between an acceptable concept of political whole and its legal and moral implications. When we face this problem, we find that widespread categories like `happiness' and "friendship" are at the same time necessary and dangerous, crucial and elusive. In order to make the case against the so-called Legal Enforcement of Morals, and to grasp the complex relationship between law and morality from a liberal point of view, it is not enough to reject a pattern of happiness, or of human flourishing, from which to draw normative instructions for men and women - it must be recognized that integration of individuals in the comprehensive groups, as well as in the political whole itself, is not the only valuable option. The fragile value of a relative lack of integration, a "right to unhappiness", turns out to be, eventually, what makes the weak, but decisive, moral primacy of liberal societies.
Brain effects of Nicotine and derived compounds
Epidemiological studies have associated tobacco consumption with a lower incidence of Alzheimer’s disease (AD) and Parkinson’s disease (PD). The neuroprotective effect of tobacco has been mainly attributed to the stimulation by nicotine of the a7 nicotinic acetylcholine receptors (nAChRs), which are implicated in neuronal survival, attention, and memory. A reduction in cholinergic function including lower levels of the expression of nAChRs in the hippocampus correlates with memory impairment in AD and schizophrenia. nicotine main metabolite cotinine shows similar neuroprotective and mnemonic properties. Also cotinine reduced Alzheimer’s pathology in a mouse model of the disease. Tobacco-derived compounds can be beneficial in a broad range of neurological disorders such as schizophrenia, AD, attention-deficit hyperactivity disorder, and PD as well as in diminishing tobacco withdrawal. In the latest years numerous new discoveries in this research area have been achieved and a Research Topic publication is needed.
