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"In the early 18th century, Piedmontese intellectuals and scientists were keen on dialoguing with colleagues and academic institutions across the Alps. They had a truly cosmopolitan approach to research and its dissemination. Physicians were particularly active, and ideas started to circulate. Turin and Piedmont found themselves within a network connecting the most important European capitals, but also their scientific societies and the universities. This stimulating environment was further enriched by the growth of the civil society: new academies were funded and scientific works were published. These became the pillars of a renewed 'cosmopolitan spirit'. During the second half of the centu...
Over the past ten years, there has been an increasing recognition that syndromes of frontotemporal dysfunction (FTD) are a common occurrence in patients with amyotrophic lateral sclerosis (ALS). Such syndromes may be present in as many as 60% of patients with ALS. Conversely, the occurrence of motor neuron dysfunction in patients with clinically pure frontotemporal dementia is increasingly recognized. This suggests that to some extent there are overlapping syndromes in which both ALS and FTD occur within the same individual. This volume summarizes the advances in our understanding of these two disorders, as well as the potential relationship between the two. Key topics include advances in our ability to clinically describe the frontotemporal syndromes, preclinical detection, neuroimaging, and genetics. The exploding field of new markers in neuropathology is examined, as is the role of new genetic mutations in DNA/RNA transport systems. This book is the essential reference text for this topic, and will be of interest to neurologists and neurological trainees with a clinical or research interest in the FTDs or ALS, neuropsychologists, neuropathologists, and researchers.
This book is an ideal and practical resource on the potential impact Artificial Intelligence (AI) can have in space sciences and applications. AI for Space Application presents a hands-on approach to browse in the subject and to learning how to do. AI is not yet fully accepted as a pervasive technology in space applications because they are often mission-critical and the cost of space equipment and modules raises skepticism on any practical use and reliability. However, it is evident that its potential impact on many aspects is dramatic. Starting from either actual or experimental realizations, the book accompanies the reader through such fascinating subjects like space exploration, autonomous navigation and landing, rover control and guidance on rough surfaces, image analysis automation for planet or star classification, and for space debris avoidance without human intervention. This kind of approach may facilitate further investigations on the same or similar subjects, as the future of space explorations is going toward adopting AI. The intended audience of the book are researchers from academia and space industries and practitioners in related start-ups.
The 2nd edition of this book incorporates the tremendous clinical advances that have occurred in the field of transcranial direct current stimulation (tDCS) over the past 5 years. Since the 1st edition was published, the clinical use of tDCS has moved from its infancy, and is now in a thrilling new phase with numerous possibilities as well as challenges. tDCS is a technique that excels in terms of safety and tolerability, and within a few years, novel technological developments will allow its use at home. At the same time, large, phase III trials have been exploring the clinical efficacy of tDCS, the results of which have been published in leading journals such as the New England Journal of ...
The aim of this book is to provide a comprehensive review of the use of Transcranial Direct Current Stimulation (tDCS) in different psychiatric conditions. Here we review tDCS clinical studies employing different types of design (from single-session tDCS studies to randomized clinical trials) as well as studies evaluating the impact of tDCS in neurophysiological, behavioral and brain imaging outcomes. Although the understanding about physiological foundations and effectiveness of clinical therapies of psychiatric diseases has been considerably increased during the last decades, our knowledge is still limited, and consequently psychiatric diseases are still a major burden to the individual pa...
Neuroimaging methodologies continue to develop at a remarkable rate, providing ever more sophisticated techniques for investigating brain structure and function. The scope of this book is not to provide a comprehensive overview of methods and applications but to provide a 'snapshot' of current approaches using well established and newly emerging techniques. Taken together, these chapters provide a broad sense of how the limits of what is achievable with neuroimaging methods are being stretched.
Human behavior and decision making is subject to social and motivational influences such as emotions, norms and self/other regarding preferences. The identification of the neural and psychological mechanisms underlying these factors is a central issue in psychology, behavioral economics and social neuroscience, with important clinical, social, and even political implications. However, despite a continuously growing interest from the scientific community, the processes underlying these factors, as well as their ontogenetic and phylogenetic development, have so far remained elusive. In this Research Topic we collect articles that provide challenging insights and stimulate a fruitful controvers...