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Micro- and Nanostructured Microfluidic Devices for Localized Protein Immobilization and Other Biomedical Applications
A new immobilization method for the localized adsorption of proteins on thermoplastic surfaces is introduced. Artificial three-phase interfaces were realized by surface structuring to control the wetting behavior which lead to a preferred adsorption in these modified areas. Additionally, different fabrication methods were analyzed to determine mass fabrication capabilities. These fabrication methods also allowed the production of fully structured microchannels to tune the fluids behavior within.
Hot Embossing
The second edition of Hot Embossing: Theory of Microreplication will present the current state of the art in microreplication with a focus on hot embossing, nanoimprint, thermoforming, and roll-to-roll replication. Polymer processing, the theory of polymers and the processing of polymers are discussed in detail. Aspects of process simulation and the corresponding material models are also covered. The book contains in-depth analysis of processing processes and replication techniques including mold fabrication. Monitoring, data analysis and reliability of molded parts is also discussed. In the Second Edition new processes are included, including the process of micro- and nanothermoforming to g...
Photon upconversion heterostructures made from surface-anchored metal-organic frameworks
This work deals with the process of photon upconversion in surface-anchored metal-organic frameworks. During the upconversion, two low-energy photons are absorbed and fused into a higher-energy photon, which is emitted. In this work, this process is analyzed in surface-bound metal-organic frameworks by spectroscopic methods. Furthermore, the application for increasing the efficiency of solar cells is discussed.
Power Generation by Resonant Self-Actuation
Die Forschung im Bereich der Mikro-Energiegewinnungssysteme wurde durch den Bedarf an autarken, stabilen Energiequellen für vernetzte drahtlose Sensoren vorangetrieben. Abwärme, insbesondere bei Temperaturen unter 200 °C, stellt eine vielversprechende, aber mit den derzeitigen Umwandlungstechnologien schwer zu gewinnende Energiequelle dar. - Research into micro energy harvesting systems has been driven by the need for self-sustaining, stable power sources for interconnected wireless sensors. Waste heat, particularly at temperatures below 200 °C, presents a promising but challenging energy source to recover using current conversion technology.
Advanced Elastocaloric Cooling Devices Based on Shape Memory Alloy Films
Elastocaloric cooling is an emerging solid-state cooling technology with the potential to provide environmentally friendly, efficient cooling. The elastocaloric effect in superelastic shape memory alloy films is used to develop advanced cooling devices for small-scale applications. Cascaded and parallelized devices are developed to increase device temperature span and cooling capacity. The concepts are proven experimentally, a maximum temperature span of 27° C is achieved in a cascaded device.
Novel MRI Technologies for Structural and Functional Imaging of Tissues with Ultra-short T₂ Values
Conventional MRI has several limitations such as long scan durations, motion artifacts, very loud acoustic noise, signal loss due to short relaxation times, and RF induced heating of electrically conducting objects. The goals of this work are to evaluate and improve the state-of-the-art methods for MRI of tissue with short T?, to prove the feasibility of in vivo Concurrent Excitation and Acquisition, and to introduce simultaneous electroglottography measurement during functional lung MRI.
NMR micro-detectors tailored for multinuclear and electrochemistry lab-on-a-chip applications
This work offers three solutions tailored to specific applications to overcome NMR challenges in the micro-domain. As the first sub-topic of this work, different potential electrode designs, compatible with NMR technique, are suggested and experimentally evaluated. As the second focus point, this work tackles multinuclear detection challenges. In parallel, a low-cost, broadband insert is discussed to enhance the sensitivity of standard NMR coils when a small sample volume is available.
X-ray optics made by X-ray lithography: Process optimization and quality control
Grating based X-ray phase contrast imaging sets out to overcome the limits of conventional X-ray imaging in the detection of subtle density differences and opens a way to characterize a sample's microstructure without the need for ultrahigh spatial resolution. The technique relies on grating structures with micrometric periods and extreme aspect ratio - their fabrication by X-ray lithography with optimal structure quality is the topic of this work.
In Situ Characterization and Modelling of Drying Dynamics for Scalable Printing of Hybrid Perovskite Photovoltaics
Hybrid perovskite photovoltaics could play a vital role in future’s renewable energy production. However, there are still severe challenges when scaling the technology. In this work, perovskite solution films drying in laminar and slot-jet air flows are investigated extensively by optical in situ characterization. The main results are a quantitative model of perovskite drying dynamics and a novel in situ imaging technique – yielding valuable predictions for large-scale perovskite fabrication.
Innovative micro-NMR/MRI functionality utilizing flexible electronics and control systems
The advantages offered by the flexible electronics and control systems technologies were utilized for tackling the challenges facing two crucial Magnetic Resonance (MR) applications. The first application is in the field of interventional Magnetic Resonance Imaging (MRI), and the other application is in the field of Nuclear Magnetic Resonance spectroscopy (NMR).
