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The term “Translational Research” reflects today’s integration of basic research (“bench”) findings with the clinical practice of medicine, and in a wider scope the application of results from the individual patient (“bedside”) to entire populations for the improvement of public health. This book offers future researchers a stimulus in many aspects of cardiovascular research, so as to promote their interest in future fields of cardiovascular disease, diagnosis and treatment. Introduction to Translational Cardiovascular Research discusses the fundamental and important aspects of the topic. It describes the renin-angiotensin-aldosterone system, the beta adrenergic receptors and t...
The ESC Textbook of Cardiovascular Imaging third edition provides extensive coverage of all cardiovascular imaging modalities. Produced in collaboration with the European Association of Cardiovascular Imaging with contributions from specialists across the globe and edited by a distinguished team of experts, it is a 'state of the art' clinically-orientated imaging reference. Now fully revised and updated with the latest imaging techniques and technology and covering even more conditions than before, it not only discusses the principles of individual modalities but also clearly demonstrates the added value each technique can bring to the treatment of all cardiac diseases. Richly illustrated wi...
This book explains in detail the potential value of the hybrid modalities, SPECT-CT and PET-CT, in the imaging of cardiac innervation in a wide range of conditions and diseases, including ischemic heart disease, diabetes mellitus, heart failure, amyloidosis, heart transplantation, and ventricular arrhythmias. Imaging of the brain-heart axis in neurodegenerative disease and stress and of cardiotoxicity is also discussed. The roles of the various available tracers are fully considered, and individual chapters address radiopharmaceutical development under GMP, imaging physics, and kinetic modeling software. Highly relevant background information is included on the autonomic nervous system of the heart and its pathophysiology, and in addition future perspectives are discussed. Awareness of the importance of autonomic innervation of the heart for the optimal management of cardiac patients is growing, and there is an evident need for objective measurement techniques or imaging modalities. In this context, Autonomic Innervation of the Heart will be of wide interest to clinicians, researchers, and industry.
The standard procedure for defining the anatomic extent andseverity of coronary artery disease is catheter-based selectivecoronary angiography. While there are advantages to coronaryangiography, it is invasive with some risk of complications andrequires a brief period of hospitalization, making it relativelyexpensive. Cardiac CT, PET and MR is a completetechnique-oriented reference, offering real alternatives to the“standard procedure”. Non-invasive techniques of coronary artery lumen imaging, suchas multislice computed tomography (MSCT) and magnetic resonanceimaging (CMR) as well as complementary and at times more usefulphysiologic and/or metabolic imaging techniques provided bypositron...
This book provides the most up-to-date coverage of the combined use of imaging modalities in order to acquire important functional and morphological information on cardiovascular disease and enhance disease detection. The recent developments in PET/MRI, cardiac CT, PET/CT and SPECT/CT and their impact on clinical practice are explained and special attention is also devoted to imaging parameters and protocols for use in practice and research. The utility of multimodality imaging techniques for diagnosis and evaluation is discussed in the context of various clinical scenarios, including ischemic cardiomyopathy, myocarditis, myocardial fibrosis, cardiac sarcoidosis and atherosclerotic plaque disease. Written by renowned researchers and clinicians, the book is an ideal concise reference on today’s most advanced imaging techniques. It will appeal to all clinicians, trainees and technicians who are involved in the diagnosis and risk assessment of cardiovascular disease.
The availability of 3D imaging in cardiology has provided a large flow of information to the clinical management of low and high risk patients. However, the correlation among different findings such as perfusion, metabolism or wall motion abnormalities is difficult and mostly qualitative. In fact labs may return information that is frequently redundant or even conflicting due to lack of correlation between different techniques in imaging. The complexity of the problem is can be reflected in the technical differences of the many imaging techniques, for example, echocardiography is based on ultrasound while angiography is based on x-rays. This text collects the experiences of different specialists, starting from the basic concepts of cardiac imaging, analyzing differences and similarities between invasive and non-invasive techniques, challenged versus the computer point of view, in order to obtain an operative efficient guide in the field of image fusion.
Written by internationally renowned experts, this volume deals with imaging of diseases of heart, chest and breast. The different topics are disease-oriented and cover all the relevant imaging modalities, including standard radiography, CT, nuclear medicine with PET, ultrasound and magnetic resonance imaging, as well as imaging-guided interventions. This book presents a comprehensive review of current knowledge in imaging of the heart and chest , as well as thoracic interventions and a selection of "hot topics" of breast imaging. It will be particularly relevant for residents in radiology, but also very useful for experienced radiologists and clinicians specializing in thoracic disease and wishing to update their knowledge of this rapidly developing field.
The complexity of issues associated with gating studies with PET imaging are mostly unknown among practitioners of the field, which is posing a significant danger to those who undergo such studies. This is particularly true for respiratory gating examination. Topics in this issue include both basic and clinical topics, including views from radiation oncology physicians.
This clinically oriented book provides an up-to-date review on the various hybrid imaging modalities that may be employed for the purpose of cardiac imaging. After discussion of generic aspects of hybrid imaging, SPECT/CT, PET/CT, and PET/MRI are each considered in depth. In addition, information is provided on upcoming technologies, such as dedicated so-called fast cardiac cameras (CZT detector technology) and novel probes and radiotracers. A wide variety of topics are addressed, including important technological aspects, possible applications, imaging protocols, peculiarities of the available modalities, radiation exposure, and dose reduction. Last but not least, an estimation of the cost efficiency of dedicated and hybrid imaging devices in cardiology is provided and possible scenarios with respect to health care economics are envisioned. Hybrid Cardiac Imaging will be of particular value for nuclear medicine specialists, cardiologists, and radiologists and will also be of interest to medical physicists, medical technicians, and cardiothoracic surgeons.
The recent development of three-dimensional imaging techniques has provided an enormous amount of information relevant to the clinical management of patients at low and high risk for coronary artery disease. However, while progress in each individual technique has been rapid, the correlation of findings obtained with radiology, nuclear medicine, and magnetic resonance imaging is still relatively neglected. In this book, qualified experts in cardiac imaging present the basic concepts of cardiac pathology and imaging and compare the findings obtained in particular subspecialties with those acquired using other techniques. In this way the reader will learn how images and techniques can be integrated in clinical practice to the benefit of the patient. In addition, it is explained how appropriate multimodality integration can reduce the patient's exposure to ionizing radiation. Physicians ranging from cardiac surgeons to internal medicine specialists and even public health administrators will find this book invaluable in understanding the role of hybrid cardiac imaging.