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Studies of receptors, ion channels, and other membrane proteins require a solid understanding of the structural principles of these important biomolecules. Membrane protein structure is, however, a very challenging field. The structures of only three types of transmembrane proteins have been determined to moderate or high resolution during the last two decades, a period during which the amino acid sequences of hundreds, if not thousands, of membrane proteins have been reported. As a result, the creation of structural models to serve as guides for studies of receptors, channels, and other membrane proteins has become crucially important. This book has been assembled in order to share the expe...
The central themes of Cell Boundaries deal with understanding the organization of lipids in bilayers and the folding, assembly, stability, and function of membrane proteins. It was written with advanced undergraduates and beginning graduate students in the biological and physical sciences in mind.
The central themes of Cell Boundaries concern the structural and organizational principles underlying cell membranes, and how these principles enable function. By building a biological and biophysical foundation for understanding the organization of lipids in bilayers and the folding, assembly, stability, and function of membrane proteins, the book aims to broaden the knowledge of bioscience students to include the basic physics and physical chemistry that inform us about membranes. In doing so, it is hoped that physics students will find familiar territory that will lead them to an interest in biology. Our progress toward understanding membranes and membrane proteins depends strongly upon t...
The central themes of Cell Boundaries concern the structural and organizational principles underlying cell membranes, and how these principles enable function. By building a biological and biophysical foundation for understanding the organization of lipids in bilayers and the folding, assembly, stability, and function of membrane proteins, the book aims to broaden the knowledge of bioscience students to include the basic physics and physical chemistry that inform us about membranes. In doing so, it is also hoped that physics students will find familiar territory that will lead them to an interest in biology. Our progress toward understanding membranes and membrane proteins depends strongly u...
This book retells the classic story of Snow White and the Seven Dwarfs and the equally compelling history of its making. It reunites a trove of its rare, surviving original conceptual and production art from the incomparable private collection of Stephen H. Ison. From the opening approach to the evil Queen's castle to the final awakening of Snow White with a kiss from her true love, each illustrated drawing freezes in time an image that had its momentary but indelible existence on the screen.
Long overdue, Beyond the Numbers is one of the first books to really examine the process of data analysis for practitioners. Educators facing the implementation of No Child Left Behind will find Dr. White's insights to be a practical approach.
Includes field staffs of Foreign Service, U.S. missions to international organizations, Agency for International Development, ACTION, U.S. Information Agency, Peace Corps, Foreign Agricultural Service, and Department of Army, Navy and Air Force