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Multiple Sclerosis Therapeutics
This book comprehensively reviews the current state of clinical trial methods in multiple sclerosis treatment, providing investigators, sponsors and specialists with current knowledge of outcome measures and study designs for disease and symptom management. The status of the rapidly evolving field of disease-modifying drugs is presented, with emphasis on the most promising therapies currently being tested. Experts discuss disease and symptom management for MS subtypes, including neuromyelitis optica and pediatric MS. In addition, key scientific advances in MS pathology, genetics, immunology and epidemiology are presented. The fourth edition has been extensively revised, featuring more than 50% new material. All chapters have been substantially updated to provide current information on rapidly evolving topics and this volume contains 15 new chapters, reflecting the growth of the field in recent years. This book is an essential reference for practitioners caring for MS patients, investigators planning or conducting clinical trials, and clinical trial sponsors.
Encyclopedia of the Human Brain
In the past decade, enormous strides have been made in understanding the human brain. The advent of sophisticated new imaging techniques (e.g. PET, MRI, MEG, etc.) and new behavioral testing procedures have revolutionized our understanding of the brain, and we now know more about the anatomy, functions, and development of this organ than ever before. However, much of this knowledge is scattered across scientific journals and books in a diverse group of specialties: psychology, neuroscience, medicine, etc. The Encyclopedia of the Human Brain places all information in a single source and contains clearly written summaries on what is known of the human brain. Covering anatomy, physiology, neuro...
Multiple Sclerosis Therapeutics
Since the publication of the previous edition of this volume, there has been substantial progress in a number of areas of multiple sclerosis (MS) research. Although immunosuppressive treatments continue to be developed and refined, more targeted immunomodulatory therapies are surfacing as we learn more about how the immune system works in health an
Psycholinguistic Approaches to the Study of Linguistic Structures
How do we understand what we hear or read? How do we do it when what we hear or read is uncommon, ambiguous, non-canonical, or unexpected? How does being bilingual or suffering from a pathology affect our ability to understand the myriad of linguistic structures around us and, consequently, our ability to use them? This edited volume brings together cutting-edge experimental studies that untangle how speakers with different profiles understand and use linguistic structures of very different natures. The reader will find a detailed overview of the experimental models and techniques that can be applied to their study from a psycholinguistic approach.
Multiple Sclerosis and Related Disorders
Multiple Sclerosis and Related Disorders provides evidence-based data and experience-based guidance for delivering quality long-term care to MS patients. Information on disease history, pathophysiology, and biology is included to provide clinicians with a framework for understanding current diagnosis, monitoring, and treatment strategies for these disorders. In addition to thoroughly reviewing the newest disease-modifying treatments, the authors have devoted significant focus to the symptoms that frequently manifest and their treatment options. Symptoms and functional limitations are the Ïface of the diseaseÓ for patients, and present their own set of challenges for practitioners. Th...
Darwin's Bridge
Darwin's Bridge: Uniting the Humanities and Sciences explores the meaning of consilience and considers the unity of human evolution, human nature, social dynamics, art, and narrative. Bringing together cutting-edge scientists and scholars across a range of fields of knowledge production, this volume makes it possible to see how far we have come toward unifying knowledge about the human species, what major issues are still in contention, and what areas of research are likely to produce further progress.
Facing the Cognitive Challenges of Multiple Sclerosis
"When attorney Jeffrey N. Gingold misplaced his wife on the living room couch and lost awareness of his children, little did he know that he was experiencing a hidden symptom of multiple sclerosis: cognitive difficulties. How do you handle getting lost, while driving just blocks from your home? Facing the Cognitive Challenges of Multiple Sclerosis is a courageous and compelling personal account of one man's anguishing struggle with this aspect of the disease. It is written for the silent majority of MS patients who are privately dealing with MS cognitive symptoms and potential disabilities. The National Multiple Sclerosis Society estimates that over 400,000 people in the U.S. have been diagn...
The Oxford Handbook of Ergativity
This volume examines the phenomenon of ergativity, a grammatical patterning whereby direct objects are in some way treated like intransitive subjects, to the exclusion of transitive subjects. It includes theoretical approaches from generative, typological, and functional paradigms, as well as 16 language-specific case studies.
