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This volume is comprised of the majority of lecture presentations and a few select posters presented at the International Workshop, "Basal Ganglia and Thalamus in Health and Movement Disorders," held in Moscow, Russia, on May 29-31, 2000. The International Committee responsible for organizing this workshop included Alexander Konovalov, Director, Burdenko Institute of Neurosurgery of the Russian Academy of Medical Sciences, Mahlon DeLong, Chair, Department of Neurology, Emory University, Atlanta, USA, Alim Louis Benabid, Chief, Neurosurgery Service, University of Joseph Fourrier, Grenoble, France, and the two undersigned. The workshop was conceived out of a desire to provide a forum for discussions of both basal ganglia-and motor thalamus-related issues by bringing together basic scientists and clinicians representing different disciplines, research directions, and philosophies. The primary goals were to encourage an exchange of information and ideas in an informal environment, to stimulate integration of the data from different disciplines, and to identifY controversial issues and the most essential questions to be addressed in future research.
This book provides a state-of-the-art overview of our current understanding of deep brain stimulation (DBS) for the treatment of neurological and psychiatric disorders. With a broad multidisciplinary scope, it presents contributions from leading experts in the field from Europe and America, who share not only their knowledge, but their experience as well. The book focuses both on basic and theoretical aspects of DBS, as well as clinical and practical aspects. It follows an evidence-based approach, and where possible offers clinical recommendations based on published guidelines. It starts with a general section, which discusses basic principles and general considerations. This is followed a sections dedicated to neurological disorders, and psychiatric disorders, in which only accepted indications are discussed. All experimental indications are discussed in the final chapter. The text is supplemented with numerous illustrations. Intended for medical specialists and residents involved in the treatment of patients with DBS, it also appeals to other professionals working with DBS patients, such as psychologists, nurses, physiotherapists, as well as basic and clinical neuroscientists.
Deep brain stimulation (DBS) is increasingly used for the treatment of patients with severe Parkinson's disease and other movement disorders, but the technique and science behind it is still poorly understood by most clinicians. This book is intended to provide an overview of the use of deep brain stimulation for movement disorders and provide an introduction to the developing arena of DBS for psychiatric disease. The first part of the book covers the varying surgical techniques involved in implanting electrodes into various deep nuclei within the brain. The neurophysiological techniques involved in this process and the complex issue of programming the implanted stimulator in order to optimise therapeutic efficacy and minimise stimulation induced adverse effects. The second part of the book describes how to select appropriate patients for DBS and describes the results of DBS treatment for Parkinson's disease, dystonia and various tremors, as well as psychiatric conditions. Edited by three of the world's leading experts in the DBS field, this pocketbook will provide neurologists, trainees and specialist nurses with an overview of the therapeutics use of DBS
Intracerebral interventions raise particular ethical issues. For instance, attempts at replacing lost or altered brain cells with the help of stem cells or the therapeutic application of Deep Brain Stimulation would have morally relevant implications. Many medically relevant questions and ethical concerns need to be clarified before these intracerebral interventions can become routine procedure: If the brain is conceived as the carrier of an individual's personality or of the self then operations on the brain can be seen as intrusions upon one's personality. The book addresses historical, philosophical, social and legal implications of these new developments in the neurosciences and aims at resolving some of the dilemmas that go hand in hand with »implanted minds«.
This volume follows on from the symposium "Brain Machine Interfaces - Implications for science, clinical practice and society", held on August 26th-29th 2010 in Ystad, Sweden, and features contributions from pioneers and leading scientists in the field of BMI and motor systems physiology, including spinal cord, basal ganglia and motor cortex. The wide range of topics covered include implants for mind control of prostheses and in robotics, clinical and experimental research on Deep Brain Stimulation (DBS) for the treatment of Parkinson's disease, depression and Alzheimer's disease, cochlear implants, retinal implants, novel flexible micro- and nano-electrode implants, safety aspects including...
Volume 49: A. delves in to Herbicides and Pesticides, which contribute to Parkinson's Disease with there genetic components as well. This is one in a series. Please watch for B,C,D,E,F,G,H,I. concerning the Herbicides and Pesticides in Parkinson's Disease Plus.
This book provides a detailed summary of the most important trials and studies in neurosurgery, allowing the reader to rapidly extract the key results of all major trials.
Key features – Covers emerging therapeutic and nutritional approaches for the treatment and management of OCD Reviews the role of various micro-nutrients in OCD Discusses the prenatal genetic diagnosis and application of computational modelling in OCD Includes the nutritional and dietary roles in neuropsychiatric disorders like depression and obsessive-compulsive disorder (OCD) Explores the application of nano-biotechnology in OCD
Deep brain stimulation (DBS) is now a firmly established treatment for movement disorders, and an increasing body of evidence supports DBS in the treatment of other neurological and psychiatric disorders. This essential reference guide outlines a practical approach to the use of this paradigm-shifting therapy and covers key aspects of DBS practice. Chapters describe how to implement a DBS program and select appropriate patients, device programming to achieve optimal symptom control, and long-term management of patients. Thoroughly revised, this third edition includes additional chapters on managing patients with emerging applications of DBS. An entire chapter is dedicated to troubleshooting common problems with the therapy as many 'failures' are preventable and addressable. With contributions from experts in the field, this is a must-have reference guide for any clinician working with DBS patients.
This work is the result of a recently held International Epilepsy Colloquium on the mesial temporal lobe epilepsies (MTLE) which covered all aspects of this specific group of syndromes (or constellations), from animal model to treatment strategies. Written by international experts from different fields, it aims to provide professionals from neuroscientists to clinical neurologists, neurosurgeons and neuropaedia-tricians dealing with mesial temporal lobe epilepsy, with a concise overview on the current body of knowledge and on emerging concepts and findings.