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A decade of technological advances and research on the human microbiome has re-defined our understanding of biological systems, and now offers diagnostic tools and new approaches to human health. Likewise, marine ecosystems are driven by their microbiome, the ensemble of microscopic organisms that inhabit the water column, sediments and aquatic organisms, and regulate most fluxes of energy and matter. While the human microbiome is composed principally of bacteria, the marine microbiome has a much broader ensemble of microscopic organisms with sizes spanning from viruses of a few tens of nanometres to metazoans of several centimetres. Advances in high throughput imaging and sequencing are eme...
This unique book addresses the bioinformatic and statistical modelling and also the analysis of microbiome data using cutting-edge QIIME 2 and R software. It covers core analysis topics in both bioinformatics and statistics, which provides a complete workflow for microbiome data analysis: from raw sequencing reads to community analysis and statistical hypothesis testing. It includes real-world data from the authors’ research and from the public domain, and discusses the implementation of QIIME 2 and R for data analysis step-by-step. The data as well as QIIME 2 and R computer programs are publicly available, allowing readers to replicate the model development and data analysis presented in each chapter so that these new methods can be readily applied in their own research. Bioinformatic and Statistical Analysis of Microbiome Data is an ideal book for advanced graduate students and researchers in the clinical, biomedical, agricultural, and environmental fields, as well as those studying bioinformatics, statistics, and big data analysis.
A sequence of elaborate close-up photographs of a diverse range of plankton organisms displays their phosphorescent beauty and translucent colors against contrasting black backgrounds while offering historical and scientific discussions for each depicted species. --Publisher's description.
This book constitutes the proceedings of the 23rd International Conference on Theory and Practice of Digital Libraries, TPDL 2019, held in Olslo, Norway, in September 2019. The 16 revised full papers,12 short papers and 18 poster papers presented were carefully reviewed and selected from 75 submissions. The general theme of TPDL 2019 was Connecting with Communities and so the papers attempt to facilitate establishing connections and convergences between diverse research communities such as Digital Humanities, Information Sciences and others that could benefit from ecosystems offered by digital libraries and repositories. To become especially useful to the diverse research and practitioner communities digital libraries need to consider special needs and requirements for effective data utilization, management and exploitation.
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This book presents the theoretical foundations of Systems Biology, as well as its application in studies on human hosts, pathogens and associated diseases. This book presents several chapters written by renowned experts in the field. Some topics discussed in depth in this book include: computational modeling of multiresistant bacteria, systems biology of cancer, systems immunology, networks in systems biology.
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