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The Structure And Function Of Ryanodine Receptors
This book provides up-to-date information on some of the most important aspects of ryanodine receptor function and has been written by experts in the field. Included are reviews of the latest experimental data, critical assessments of the mechanisms of ryanodine receptor activation and regulation, and the role of the channel in controlling intracellular Ca2+ release.The approach to this subject is new. The book focuses on the biochemical and biophysical aspects of ryanodine receptor research, with particular emphasis on the single channel properties of reconstituted ryanodine receptors.
Ryanodine Receptors
In recent years, the ryanodine receptor has emerged as a new and very promising target for the treatment of several cardiovascular disorders, including cardiac arrhythmias and heart failure. This volume is the most current publication devoted to the major intracellular calcium-release channel, the ryanodine receptor. "In this series of brief but informative chapters, the contributions progress from the basic gene family and primary structure, through its 3D structure so far, to its regulation and physiology." David E. Clapham, MD, PhD Professor of Neurobiology and Pediatrics Harvard Medical School Dr. Xander H.T. Wehrens received his M.D. and Ph.D. degrees from Maastricht University in the N...
I, Eliza Hamilton
The strong-willed, heroic wife of Alexander Hamilton tells her story in this historical novel by the bestselling author of The Secret Wife of Aaron Burr. As the daughter of a respected general, Elizabeth Schuyler is accustomed to socializing with dignitaries and soldiers. But no visitor to her parents’ home has affected her so strongly as Alexander Hamilton, a charismatic, ambitious aide to George Washington. They marry quickly, and despite the tumult of the American Revolution, Eliza is confident in her husband and in her role as his helpmate. But it is in the aftermath of war, as Hamilton becomes one of the country’s most important figures, that she truly comes into her own In the new ...
