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Diabetes Mellitus
Thoroughly revised and updated, this Third Edition encompasses the most recent advances in molecular and cellular research and describes the newest therapeutic modalities for type 1 and type 2 diabetes mellitus. Chapters by leading experts integrate the latest basic science and clinical research on diabetes mellitus and its complications. The text is divided into ten major sections, including extensive sections on therapeutics, diabetes during pregnancy, and complications. New chapters cover stem cell therapy for type 1 diabetes; genetics and treatment of obesity; new therapies to promote insulin action; vasculopathy; islet cell protocols; triglycerides in muscle; hypoglycemia in the adult; and the Diabetes Prevention Program.
Guide
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Sleep Loss and Obesity
Sleep Loss and Obesity: Intersecting Epidemics represents a major contribution to the field of sleep medicine. It is a comprehensive review of the neurobiology of sleep, circadian timing and obesity, the deleterious effects of sleep loss and obesity on health, and the worrisome associated social and medical costs in a range of patient populations and overall to society. The number of individuals who are obese has reached alarming levels. As a result, the incidence of Type 2 diabetes, cardiovascular disorders, heart disease, and kidney failure have also increased. The surgeon general estimates that the total annual cost of obesity in the US is about $117 billion. This cost is expected to esca...
The role of the immune system in the pathogenesis of diabetic complications
The main causes of morbidity and mortality in diabetes are macrovasular and microvascular complications, including atherosclerosis, nephropathy, and retinopathy. As the definition of atherosclerosis as a chronic, smoldering, inflammatory disease has gained general acceptance, the attention of researchers has focused on the triggers of chronic vascular inflammation. The oxidation and other forms of modification of lipids and lipoproteins have emerged as a major pathogenic factor in atherosclerosis, with a significant interaction with the immune system. Modified lipoproteins by themselves are proinflammatory through the activation of the innate immune system as a consequence of the interaction...
Intimate Strangers
Zooming in on commercial surrogacy in Russia and Ukraine, Intimate Strangers addresses market expansion into the intimate spheres of life that play out on women's bodies as mothers and workers. Veronika Siegl follows the inner workings of a surrogacy market marked by secrecy, distrust, and anonymous business relationships. She explores intended mothers' anxious struggles for a child in light of stigmatized infertility and the aggressive biopolitics of motherhood; the uncertain but pragmatic pathways in and out of fertility clinics as surrogates navigate harsh economic realities and resist being objectified or morally judged; and the powerful role of agents and doctors who have found a profitable niche in nurturing and facilitating other people's existential hopes. Intimate Strangers discusses these issues against the backdrop of ultra-conservatism and moral governance in Russia, the rising international popularity of the Ukrainian surrogacy market, and the pervasiveness of neo-liberal ideologies and individualized notions of reproductive freedom.
