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Up-to-date information on animal models generated by transgenic or gene targeting techniques. Naturally, the focus is on the mouse system. Each chapter has been written by leading experts in the field and gives an overview on existing animal models. This is facilitated by tables, which list the most important genetically engineered animal models and their phenotypes. This book aims at illustrating the impact of transgenic animal models in the field of Experimental Pharmacology and Toxicology, which includes their role in the understanding of basic cellular mechanisms, the evaluation of potential drug targets or the testing for drug effects.
This book has been prepared under the auspice of the European Low Gravity Research Association (ELGRA). The main task of ELGRA is to foster the scientific community in Europe and beyond in conducting gravity and space-related research.This publication is dedicated to the science community, and especially to the next generation of scientists and engineers interested in space research and in the means to use Earth to reproduce the space environment. ELGRA provides a comprehensive description of space conditions and the means that have been developed on Earth to perform space environmental and (micro-) gravity related research. .The book covers ground-based research instruments and environments...
The reauthorization of the U.S. Elementary and Secondary Education Act, referred to as the Every Student Succeeds Act (ESSA), emphasizes evidence-based interventions while giving states and districts new flexibility on the use of federal funds, including funds that could be used to support social and emotional learning (SEL). The authors review recent evidence on U.S.-based SEL interventions for K-12 students to better inform the use of SEL interventions under ESSA. This report discusses the opportunities for supporting SEL under ESSA, the standards of evidence under ESSA, and SEL interventions that meet the standards of evidence and might be eligible for federal funds through ESSA. Federal, state, and district education policymakers can use this report to identify relevant, evidence-based SEL interventions that meet their local needs. A companion volume (available on the website) catalogues these interventions in more detail and outlines the research that has examined them.
The Letter-Books of Sir Amias Poulet is an unchanged, high-quality reprint of the original edition of 1874. Hansebooks is editor of the literature on different topic areas such as research and science, travel and expeditions, cooking and nutrition, medicine, and other genres. As a publisher we focus on the preservation of historical literature. Many works of historical writers and scientists are available today as antiques only. Hansebooks newly publishes these books and contributes to the preservation of literature which has become rare and historical knowledge for the future.
Southeast Asia possesses the mots biologically diverse coral reefs on the planet; and they are severely threatened by human activities. This is a detailed evalution of the threats from over-fishing, pollution, development and more, and makes several recommendations for improved management.
Originally published in 1930 in an edition of 100 copies, Gertrude Stein’s Dix Portraits pairs her singular literary style with original lithographs by Pablo Picasso and other artists in Stein’s circle to create an exceptional artist’s book exploring written and visual portraiture. Written between 1913 and 1929, revolutionary years in art history, Dix Portraits conveys the deep human engagement between an artist and her subject. The artist’s book unites Stein’s ten portraits in prose with sketches by five artists: Pablo Picasso, Christian Bérard, Eugene Berman, Pavel Tchelitchew, and Kristians Tonny. Utilizing the interplay between word and image, Stein’s writing and the artists...