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Umbilical cord blood, previously discarded, has emerged as a new source of stem cells for hematologic reconstitution, bone marrow failures and other hematologic deficiencies. It has become increasingly clear that umbilical cord tissue contains unique stem cells of great potential for regenerative medicine. Importantly, umbilical cord blood is abundant, can be banked and transported with ease, and thus has an indisputable potential for future regenerative therapies. Driven by a massive interest for regenerative medicine and ethically acceptable stem cell sources, the scientific literature on umbilical cord stem cells has exploded.This book provides a consolidated overview of basic, translatio...
Most human tissues do not regenerate spontaneously. Cell therapy and tissue engineering, which involve collecting cells from either the patient or a donor and introducing them into injured tissues or organs, sometimes after modifying their properties, offer promising solutions for regenerative medicine. Indeed, so promising are these therapies that current research has shifted from organ growth to cell therapy. The range of therapeutic applications is wide, including cardiac insufficiency, atherosclerosis, cartilage defects, bone repair, burns, diabetes and liver or bladder regeneration.This book, whilst not covering all aspects
Stem Cell Labeling for Delivery and Tracking Using Noninvasive Imaging provides a comprehensive overview of cell therapy imaging, ranging from the basic biology of cell therapeutic choices to the preclinical and clinical applications of cell therapy. It emphasizes the use of medical imaging for therapeutic delivery/targeting, cell tracking, and determining therapeutic efficacy. The book first presents background information and insight on the major classes of stem and progenitor cells. It then describes the main imaging modalities and state-of-the-art techniques that are currently employed for stem cell tracking. In the final chapters, leading scholars offer clinical perspectives on existing...
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