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Scan Statistics
In many statistical applications, scientists have to analyze the occurrence of observed clusters of events in time or space. Scientists are especially interested in determining whether an observed cluster of events has occurred by chance if it is assumed that the events are distributed independently and uniformly over time or space. Scan statistics have relevant applications in many areas of science and technology including geology, geography, medicine, minefield detection, molecular biology, photography, quality control and reliability theory and radio-optics.
Statistical Issues in Drug Research and Development
This book is a compilation of topics addressed by the ASA Biopharmaceutical Section work groups, including the etiology and evolution of the work groups, the work group guidelines and structure, and the statistical issues associated with clinical trials in clinical drug development programs.
Suicide Postvention in the Department of Defense
A review of the scientific evidence on suicide postvention (organizational responses to prevent additional suicides and help loss survivors cope), guidance for other types of organizations, and the perspectives of the family and friends of service members who have died by suicide provide insights that may help the U.S. Department of Defense formulate its own policies and programs in a practical and efficient way.
The War Within
The increase in suicides among military personnel has raised concern. This book reviews suicide epidemiology in the military, catalogs military suicide-prevention activities, and recommends relevant best practices.
Liberalism's Troubled Search for Equality
Debate surrounding the 1994 Oregon Death with Dignity Act, the first law to legalize physician-assisted suicide (PAS) in America, revealed some surprising contradictions. Most prominently, egalitarian liberal philosophers Ronald Dworkin and John Rawls backed a constitutional right to PAS in direct opposition to many groups of disadvantaged citizens they theoretically supported. These groups argued that legalized PAS in the absence of universal access to health care would potentially coerce the disadvantaged to end their lives prematurely because of inadequate financial resources. In Liberalism's Troubled Search for Equality, Robert P. Jones asks why these concerns were dismissed by liberal philosophers and argues that this contradiction exposes a blind spot within liberal political theory.
Statistics In the Pharmaceutical Industry, 3rd Edition
This rewritten and updated second edition provides comprehensive information on the wide-ranging applications of statistics in the pharmacological field. Focusing on practical aspects, it sets out to bridge the gap between industry and academia.;Reflecting the changes that have taken place since publication of the first edition, this volume covers new topics such as: cancer clinical trials, clinical trials of AIDS patients and animal tumorigenicity studies; the development of antiepileptic drugs; the role of epidemiology in postmarketing trials and adverse drug experience; computer-assisted new drug application (CANDA) submissions; contract research organizations; interim analysis in clinical trials; and room-temperature tests for the stability of drugs.;This work is intended as: a reference for statisticians, biostatisticians, pharmacologists, administrators, managers, and scientists in the pharmaceutical industry; and a text for graduate students taking courses in applied statistics or pharmaceutical statistics.
Chaos: A Statistical Perspective
This book discusses dynamical systems that are typically driven by stochastic dynamic noise. It is written by two statisticians essentially for the statistically inclined readers. It covers many of the contributions made by the statisticians in the past twenty years or so towards our understanding of estimation, the Lyapunov-like index, the nonparametric regression, and many others, many of which are motivated by their dynamical system counterparts but have now acquired a distinct statistical flavor.
Scan Statistics and Applications
The study of scan statistics and their applications to many different scientific and engineering problems have received considerable attention in the literature recently. In addition to challenging theoretical problems, the area of scan statis tics has also found exciting applications in diverse disciplines such as archaeol ogy, astronomy, epidemiology, geography, material science, molecular biology, reconnaissance, reliability and quality control, sociology, and telecommunica tion. This will be clearly evident when one goes through this volume. In this volume, we have brought together a collection of experts working in this area of research in order to review some of the developments that h...
