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At Frontiers our mission is to make science open – so that scientists can collaborate better and innovate faster to deliver the solutions that enable healthy lives on a healthy planet. We do this through our community driven Open Access journals. As researchers across the globe work on tackling the challenges facing immunology in the field of Microbial Immunology, they publish their success stories. However, it is equally important for researchers to discuss the challenges they face on the road to success, as most innovation begins with failure. Our Open Access publication allows researchers to discover the areas for development in the field and to provide a focus for future research. This Research Topic will highlight the importance of learning from one another in the scientific community and continue to highlight areas for progress. This Research Topic welcomes Reviews, Mini-reviews, Original Research, and Perspectives that highlight the field of Microbial Immunology from the following perspectives: - Recent success stories with a focus on the challenges faced and overcame. - Current challenges in the field and emerging research to innovate.
Members of the genus Staphylococcus play important roles in disease causation in humans and animals. Over the past decade, the completed sequencing of many staphylococcal genomes has contributed to a surge in the number of publications, which have promoted a tremendous advance in our knowledge of these important pathogens. Significant developments include the emergence of new and highly virulent strains of S. aureus, advances in tracking the evolution of human and animal adapted strains, a heightened appreciation of the role of mobile genetic elements in antibiotic resistance and pathogenesis, and important insights into staphylococcal physiology, immune evasion strategies, and cell surface proteins, as well as significant advances in vaccine development and therapeutics. This Research Topic will focus attention on the latest developments in these areas as they pertain to S. aureus and members of the coagulase-negative Staphylococci, and will also strive to identify areas of future development.
This standard-setting textbook has defined the field of immunology since 1984, and is now in its Seventh Edition continuing to deliver the detailed, authoritative, and timely coverage readers expect. This comprehensive, up-to-date text is ideal for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role. Now full-color throughout the book’s fully revised and updated content reflects the latest advances in the field. Current insights enhance readers’ understanding of immune system function. The text’s unique approach bridges the gap between basic immunology and the disease process. Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. Abundant illustrations and tables deliver essential information at a glance. Plus a convenient companion website features the fully searchable text and image bank! This is the tablet version of Fundamental Immunology which does not include access to the supplemental content mentioned in the text.
Influenza virus infections lead to thousands of deaths worldwide annually and billions of dollars economic burden. Despite continuing advances in our understanding of the immune evasion mechanism, the disease remains one of the foremost threat for human being. Traditional vaccines (attenuated and inactivated) mainly provide protection by inducing virus neutralizing antibodies, targeting ever changing surface antigens: Haemagultinin (HA) and Neuraminidase (NA). Due to genetic shift and immune selection pressure, prevalence of circulating influenza virus subtypes changes every year. Therefore, mismatch between circulating strain and vaccine strain can critically affect the success rate of thes...
This book discusses how greener synthetic pathways are amenable and productive for the synthesis of novel nanomaterials. It furthers the integration of advances in green nanoscience and nanotechnology, including pathways dedicated to the design, development, and fabrication of a range of products and devices. Topics such as green nanotechnology for advanced energy systems, sustainable delivery systems, medicine, agri-nanotechnology for sustainable agriculture, nanotechnology in crop protection, and nanotechnology for soil conservation are included. FEATURES Provides a holistic view of green nanotechnology and its applications Places an emphasis on synthesis, characterization, and applications of green nanomaterials Discusses the development of innovative green synthetic pathways to produce novel biomaterials Includes characterization tools used in the material synthesis via green synthetic pathways Advocates green nanotechnology solutions for sustainability and energy This book is aimed at researchers and professionals in nanotechnology, green chemistry, and chemical engineering.
Many businesses profess to be voluntarily taking steps to protect the environment, and going beyond compliance with environmental regulations to do so. Kurt Strasser evaluates these claims in this timely and cuttingedge inquiry.
Natural antibodies (NAbs) are found in normal individuals in the absence of exogenous antigenic stimulation. Natural antibodies rapidly recognize and protect against pathogens that have not been previously encountered. NAbs also cross-react with several self-antigens, which, besides their role as a first line of defense against pathogens, affords them the ability to perform important housekeeping functions in healthy organisms. Such housekeeping functions include the clearance of oxidized damaged structures and/or apoptotic cells, which prevents the induction of pro-inflammatory effects. In addition, NAbs play a role in preventing the expansion of specific auto-reactive clones, thereby behav...