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The discipline of Synthetic Biology has recently emerged at the interface of biology and engineering. The definition of Synthetic Biology has been dynamic over time ever since, which exemplifies that the field is rapidly moving and comprises a broad range of research areas. In the frame of this Research Topic, we focus on Synthetic Biology approaches that aim at rearranging biological parts/ entities in order to generate novel biochemical functions with inherent metabolic activity. This Research Topic encompasses Pathway Engineering in living systems as well as the in vitro assembly of biomolecules into nano- and microscale bioreactors. Both, the engineering of metabolic pathways in vivo, as...
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
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The accession by the European Union to the European Convention on Human Rights (ECHR) has opened up new possibilities in terms of the constitutional recognition of fundamental rights in the EU. In the field of employment law it heralds a new procedure for workers and trade unions to challenge EU law against the background of the ECHR. In theoretical terms this means that EU law now goes beyond recognition of fundamental rights as mere general principles of EU law, making the ECHR the 'gold standard' for fundamental (social) rights. This publication of the Transnational Trade Union Rights Working Group focuses on the EU and the interplay between the Strasbourg case law and the case law of the...
There currently is no in-depth book dedicated to the challenge of the Internet of Everything and Big Data technologies in smart cities. Humankind today is confronting a critical worldwide portability challenge and the framework that moves cities must keep pace with the innovation. Internet of Everything and Big Data: Major Challenges in Smart Cities reviews the applications, technologies, standards, and other issues related to smart cities. This book is dedicated to addressing the major challenges in realizing smart cities and sensing platforms in the era of Big Data cities and Internet of Everything. Challenges vary from cost and energy efficiency to availability and service quality. This book examines security issues and challenges, addresses the total information science challenges, covers exploring and creating IoT environment-related sales adaptive systems, and investigates basic and high-level concepts using the latest techniques implemented by researchers and businesses. The book is written for analysts, researchers, and specialists who are working on the future generation of the technologies. It will serve as a valuable guide for those in the industry, and students as well.
Germ cells have a unique and critical role as the conduit for hereditary information. The issue of male germline mutagenesis and the effects on developmental defects in the next generation has become increasingly high profile in recent years. Understanding the mechanisms by which the germline is induced and maintained is one of the effective ways to treat infertility and cancer. Male-mediated Developmental Toxicity discusses these issues and provides analysis of the fundamental mechanisms of mutations covering both clinical and experimental aspects. It helps clarify the data explaining how genotoxicity involves multiple modes of action and highlights novel models and assays being used to assess germ cell genotoxicity. With a clear focus on the various mechanisms that could impact human health, this book is for postgraduate students and researchers in reproductive and developmental toxicology as well as those with an interest in the fields of genetically inherited diseases, developmental biology and, potentially, those with a more clinical background.