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Biomaterials associated infection (BAI) is one of the most common complications associated with implantation of any biomaterial regardless of form or function. These infections usually involve bacterial colonization and biofilm formation on the biomaterial itself, rendering the infection impervious to antimicrobials and host defenses. In addition, it is becoming increasingly clear that infection of the surrounding tissues also plays an important role in BAI, and that the infection may be influenced by the composition and design of the implanted biomaterial. In this book, worldwide leaders in the field address this critical problem in the translation of biomaterials research into clinical pra...
Infections of the bones (osteomyelitis) and joints (septic arthritis) are serious health problems which require antibiotics and often surgery. Awareness among health professionals of the causes and treatment options for various types of bone and joint infections is essential for effective resolution. Bone and Joint Infections takes a multidisciplinary approach in covering the diagnostic and therapeutic treatment of osteomyelitis and septic arthritis, including different types of implant-associated infections. Correct and rapid diagnosis of bone and joint infection is crucial, and requires the input of a variety of specialists. Bone and Joint Infection takes a similarly collaborative and comprehensive approach, including chapters authored by clinicians, laboratory specialists, and surgeons. Covering the basic microbiology and clinical aspects of bone and joint infection, this book will be a valuable resource both for researchers in the lab and for physicians and surgeons seeking a comprehensive reference on osteomyelitis and septic arthritis.
With BAI being one of the most common complications associated with implantation of any biomaterial, this vital book features contributions from leaders in the field who address this critical problem in applying biomaterials research to clinical practice.
Bacteria and fungi are able to aggregate together or on surfaces in densely packed microcolonies, facilitated by extracellular polymeric substances for cell protection and stability. These biofilms have proven to be extremely hard to eradicate and remove once established. In chronic infections, this condition can result in a high degree of morbidity and mortality as regular antibiotic treatments are ineffective against biofilms. In industrial facilities, the formation of biofilms can ruin production and result in enormous financial losses. In this book, the current state of antibiofilm research is presented by experts from around the world. Novel, cutting-edge techniques and new optimized st...
PEEK biomaterials are currently used in thousands of spinal fusion patients around the world every year. Durability, biocompatibility and excellent resistance to aggressive sterilization procedures make PEEK a polymer of choice, replacing metal in orthopedic implants, from spinal implants and hip replacements to finger joints and dental implants. This Handbook brings together experts in many different facets related to PEEK clinical performance as well as in the areas of materials science, tribology, and biology to provide a complete reference for specialists in the field of plastics, biomaterials, medical device design and surgical applications. Steven Kurtz, author of the well respected UH...
BONE AND JOINT INFECTIONS Explore this comprehensive presentation of bone and joint infections, including non-implant and implant-associated orthopedic infections In the newly revised Second Edition of Bone and Joint Infections: From Microbiology to Diagnostics and Treatment, accomplished researcher and author Werner Zimmerli delivers a comprehensive overview of the most recent developments in the subject of bone and joint infection. Covering much of the new information appearing over the last five years, the book includes four new chapters presenting the diagnostic approach in bone and joint infections, discussing the identification of pathogens by non-culture techniques, management of mult...
This textbook emphasizes the fundamentals of bone fracture and its fixation, including advanced techniques of osteosynthesis in both small and large animals. Various fracture fixation techniques and devices have been described in simple language with the help of sketches and photographs. The chapter on the basic considerations in fracture fixation narrates bone structure and types, bone development and growth regulation, types of fracture and fracture healing, first aid and emergency treatment, selection of fracture fixation technique, anesthetic management, and fracture fixation implants and instruments. The book highlights principles of different external, internal, and external skeletal f...
This book provides detailed guidance on the recognition and treatment of the complications most frequently encountered in patients who undergo temporomandibular joint surgery. Evidence-based guidelines are referred to whenever possible, and when such guidelines are lacking, the preferred current approaches to diagnosis and management are described. In addition, the pathophysiology of each complication is discussed and advice offered on how to ensure that the correct surgical procedure is chosen for the individual patient, thereby minimizing the risk of complications. Illustrative cases are included to further highlight key points. The authors are experienced surgeons and pioneers in the field of temporomandibular joint surgery. Complications of Temporomandibular Joint Surgery will be of value for all who work in this technically very challenging field and regularly have to deal with the issues posed by a difficult patient population and the risk of suboptimal outcomes.
The work is a source of modern knowledge on biomineralization, biomimetics and bioinspired materials science with respect to marine invertebrates. The author gives the most coherent analysis of the nature, origin and evolution of biocomposites and biopolymers isolated from and observed in the broad diversity of marine invertebrate organisms and within their unusual structural formations. The basic format is that of a major review article, with liberal use of references to original literature. There is a wealth of new and newly synthesized information, including dozens of previously unpublished images of unique marine creatures and structures from nano- to microscale including high-resolution...