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"The volume focuses on recent advances in organofluorine chemistry directed towards selective fluorine introduction into various target molecules, employing both traditional and contemporary, electrophilic and nucleophilic, fluorinating agents. It brings t"
Climate change is an issue that is highly debated around the globe. This book brings together the papers that were presented at a conference dedicated to this issue, held in Kyoto in October 2002. Covering a broad range of areas, the topics presented will benefit both those working in the field of carbon dioxide recovery and sequestration, and those looking at the effects of non carbon dioxide greenhouse gases. An overview of the Research and Design technologies which aid in mitigating climate change is included, which will be invaluable to those researching new opportunities for dealing with this problem. An area of research that has seen a rapid rise in worldwide spend Will benefit both researchers in climate change, and those looking at new technologies to help deal with the problem Presents papers from contributors spread around the globe means that this book has world wide relevance
Based on topics presented at the Annual Japanese (Quantitative) Structure-Activity Relationship Symposium and the Biennial China-Japan Drug Design and Development conference, the topics in this volume cover almost every procedure and subdiscipline in the SAR discipline.They are categorized in three sections. Section one includes topics illustrating newer methodologies relating to ligand-receptor, molecular graphics and receptor modelling as well as the three-dimensional (Q)SAR examples with the active analogue approach and the comparative molecular field analysis. In section 2 the hydrophobicity parameters, log P (1-octanol/water) for compound series of medicinal-chemical interest are analysed physico-organic chemically. Section 3 contains the examples based on the traditional Hansch QSAR approach.A variety of methodologies and procedures are presented in this single volume, along with their methodological philosophies.
The genomic revolution has opened up systematic investigations and engineering designs for various life forms. Systems biology and synthetic biology are emerging as two complementary approaches, which embody the breakthrough in biology and invite application of engineering principles. Systems Biology and Synthetic Biology emphasizes the similarity between biology and engineering at the system level, which is important for applying systems and engineering theories to biology problems. This book demonstrates to students, researchers, and industry that systems biology relies on synthetic biology technologies to study biological systems, while synthetic biology depends on knowledge obtained from systems biology approaches.
This book provides concise and cutting-edge studies on threats resulting from exposure to environmental chemicals that can affect human health and development, with a particular emphasis on the DOHaD concept. The book is divided into five main parts, the first of which includes an introduction to the impacts of developmental exposure to environmental chemicals and historical perspectives, while the second focuses on how environmental chemicals can affect human organs, including neurodevelopment, immune functions, etc. In turn, the third part addresses the characteristics of specific chemicals and their effects on human health and development, while the fourth part provides a basis for future...
The Oregon Convention Center, Portland, Oregon, was the venue for the 1997 Cryogenic Engineering Conference. The meeting was held jointly with the International Cryogenic Materials Conference. John Barclay, of the University of Victoria, and David Smathers, of Cabot Performance Materials, were conference chairmen. Portland is the home of Northwest Natural Gas, a pioneer in the use of liquid natural gas, and Portland State University, where cryogenic research has long been conducted. The program consisted of 350 CEC papers, considerable more than CEC-95. This was the largest number of papers ever submitted to the CEC. Of these, 263 papers are published here, in Volume 43 of Advances in Cryoge...
The problem of the long-term proliferation of cells is a seminal one. It has always been a hot subject in biology, a source of far-reaching hypotheses, even more so now when explanations for the mechanisms of cell prolifera tive mortality or immortality seem within our reach. A question which is still debated is whether an infinite division potential can be a normal trait or is always the result of modifications leading to abnormal cell growth and escape from homeostasis. In general, investigators have been advocates of one of the two extremes, universal limited or unlim ited normal proliferative potential. Since the long-term proliferative potential of cells concerns regulation of development, regeneration of tissues, and homeostatic control of cell growth, in brief survival of living organisms, and since the regulation of these processes is so different along the evolutionary scale, it is not surpris ing that there does not seem to be any universal trait. The question of whether cells are endowed with finite or infinite prolifera tive phenotypes has to be seen using the perspective of comparative biology.
An introduction to general theories of stochastic processes and modern martingale theory. The volume focuses on consistency, stability and contractivity under geometric invariance in numerical analysis, and discusses problems related to implementation, simulation, variable step size algorithms, and random number generation.
Presents the fundamental physics of piezoelectric sensors. Only book with this scope Targeted to those engineers, phycisists and chemists who are involved in materials processing, device design and manufacturing.