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Enzymatic Basis of Detoxication Volume 1
Enzymatic Basis of Detoxication, Volume I focuses on the catalytic mechanisms and physiological expression of the enzymes that are involved in the detoxication of foreign compounds. The book explores foreign compound metabolism at the level of what specific enzymes can do. This book is organized into three sections and comprised of 17 chapters. The discussion begins with an overview of detoxication and covers both catalytic and non-catalytic removal of foreign substances, along with the general properties of the enzymes that are active in detoxication. The reader is then introduced to the physiological aspects of detoxication, paying particular attention to the kinetic aspects of metabolism ...
Pharmacology and Pharmacokinetics
This collection of papers by leading pharmacokineticists and pharmacolo gists is the proceedings of a conference held at the John E. · Fogarty International Center for Advanced Study in the Health Sciences, National Institutes of Health, October 30 to November 1, 1972. As part of its advanced study program, the Center conducts workshops, seminars, and conferences on topics related to the biomedical interests of the Scholars-in Residence. Professor Torsten Teorell came to the Center in 1970 as one of the first Scholars. In 1971 and 1972, he spent several months at the Center devoting his attention to contemporary problems in the application of pharmacoki netics to experimental and clinical p...
Self-Organization in Electrochemical Systems II
This is the second of two volumes offering the very first comprehensive treatise of self-organization and non-linear dynamics in electrochemical systems. The first volume covers general principles of self-organization as well as temporal instabilities. The content of both volumes is organized so that each description of a particular electrochemical system is preceded by an introduction to basic concepts of nonlinear dynamics, in order to help the reader unfamiliar with this discipline to understand at least fundamental concepts and the methods of stability analysis. The presentation of the systems is not limited to laboratory models but stretches out to real-life objects and processes, including systems of biological importance, such as neurons in living matter. Marek Orlik presents a comprehensive and consistent survey of the field.
Ion Exchangers
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Membrane and Desalination Technologies
In this essential new volume, Volume 13: Membrane and Desalination Technologies, a panel of expert researchers provide a wealth of information on membrane and desalination technologies. An advanced chemical and environmental engineering textbook as well as a comprehensive reference book, this volume is of high value to advanced graduate and undergraduate students, researchers, scientists, and designers of water and wastewater treatment systems. This is an essential part of the Handbook of Environmental Engineering series, an incredible collection of methodologies that study the effects of pollution and waste in their three basic forms: gas, solid, and liquid. Chapters adopt the series format...
Quantification of Circulating Proteins
Less than 50 years ago it was discovered that steady-state protein concentrations in plasma are the net result of continuous elimination and synthesis of protein molecules. The first quanti tative studies on the turnover and distribution of plasma pro teins were made around 1950, after the introduction of radio labeled protein preparations. Around 1970, another development in quantitative interpre tation of circulating proteins was initiated in clinical enzy mology. Estimation of cumulative release into plasma of cellular enzymes can be helpful in a variety of diseases to assess the extent of tissue damage and to evaluate therapy. Enzymes can be considered as biological tracers, i.e. minute ...
Smart Hydrogel Modelling
The science of mathematical modelling and numerical simulation is generally accepted as the third mode of scienti?c discovery (with the other two modes being experiment and analysis), making this ?eld an integral component of c- ting edge scienti?c and industrial research in most domains. This is especially so in advanced biomaterials such as polymeric hydrogels responsive to biostimuli for a wide range of potential BioMEMS applications, where multiphysics and mul- phase are common requirements. These environmental stimuli-responsive hydrogels are often known as smart hydrogels. In the published studies on the smart or stimu- responsive hydrogels, the literature search clearly indicates that...
Bioelectrochemistry: General Introduction
Volume 1 of this Series is intended to give the reader a fundamental understanding of the key areas deemed essential to the study of bioelec trochemistry. A thorough grasp of the theory and methodology of these basic topics is vital to cope successfully with the complex phenomena that currently face investigators in most bioelectrochemical laboratories. Chapter 1 outlines the nonequilibrium thermodynamics and kinetics of the processes involved, stressing the connection between the two ap proaches. Particular emphasis is placed on the enzymes catalyzing cytosolic reactions and membrane transport. The techniques discussed are sufficient for the study of systems in the steady state, but systems that are evolving towards the steady state, or show some other time-depen dent behavior, require in addition the techniques of mathematical modelling. These are dealt with in some detail in Chapter 2, where network representation of the system is treated at length as the method of choice in carrying out appropriate simulations. In Chapter 3 attention is directed to the twin problems of water structure and ionic hydration.
Electrochemical Kinetics
Electrochemical Kinetics: Theoretical Aspects focuses on the processes, methodologies, reactions, and transformations in electrochemical kinetics. The book first offers information on electrochemical thermodynamics and the theory of overvoltage. Topics include equilibrium potentials, concepts and definitions, electrical double layer and electrocapillarity, and charge-transfer, diffusion, and reaction overvoltage. Crystallization overvoltage, total overvoltage, and resistance polarization are also discussed. The text then examines the methods of determining electrochemical reaction mechanisms, including examination of the overall electrode reaction and determination of the type of overvoltage and reaction kinetics. A list of frequently used symbols is also provided. The book is a valuable reference for readers interested in the study of electrochemical kinetics.
Laboratory Techniques in Membrane Biophysics
The present manual contains a collection of laboratory instructions used during an international training course on membrane biophysics which was held at Homburg in the fall of 1966. The selection of the topics dealt with in the various chapters depended on the scientific interest of the available teachers and on the availability of the necessary equipment in our laboratories. Thus, the material included in this volume does not add up to a systematic course in membrane biophysics. Instead it represents a more fortuitous collection of laboratory problems. In addition, some authors place more emphasis on teaching the more technical aspects of a method whereas others are primarily concerned wit...
