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The book takes the reader through definitions of the pharmacodiagnostic concept, historical perspectives of the early steps into molecular cancer diagnostics linked to therapy, ongoing research, assay validation, clinical trial methodology, regulatory issues around pharmacodiagnostics and future aspects within personalized cancer medicine.
Biomedical Engineering is defined as the science that integrates medical and engineering sciences to improve diagnosis and treatment of patients. Only by this integration progress can be achieved. Both medical and engineering sciences comprise a huge diversity in topics, so it is imaginable that Biomedical Engineering, combining these two science areas, is even more huge. Thanks to this megadisciplinary approach many breakthroughs can be achieved. More and more research groups realize this and start new research projects, which results in a rapid increase in knowledge in Biomedical Engineering. This will only benefit the main goal of Biomedical Engineering; improving diagnosis and treatment ...
HealthGrid 2008 is the sixth conference in this series of open forums for the integration of grid technologies and its applications in the biomedical, medical and biological domains to pave the path to an international research area in healthgrids. The main objective of the HealthGrid conference and the HealthGrid Association is the exchange and discussion of ideas, technologies, solutions and requirements that interest the grid and the life-sciences communities to foster the integration of grids into health. Subjects in this publication reflect the diversity of mature practice: Advancing Virtual Communities, offering a glimpse of the kind of communities that are brought together by means of collaboration grids; Public Health Informatics, exploring the diffusion of grid concepts and technologies in health informatics; Translational Bioinformatics, the contact point between medicine, healthcare and genomics; and Knowledge Management and Decision Support, one direction that is confidently expected to grow as the synergy of grids and 'evidence-based practice' in healthcare is exploited.
We humans are tribal, grouping ourselves by a multitude of criteria: physical, intellectual, political, emotional, etc. The Internet and its auxiliary technologies have enabled a novel dimension in tribal behavior during our recent past. This growing connectivity begs the question: will individuals and their communities come together to solve some very urgent global problems? At MMVR, we explore ways to harness information technology to solve healthcare problems - and in the industrialized nations we are making progress. In the developing world however, things are more challenging. Massive urban poverty fuels violence and misery. Will global networking bring a convergence of individual and t...
Current demographic, economic and social conditions which developed countries are faced with require a paradigm change for delivering high quality and efficient health services. In that context, healthcare systems have to turn from organization-centered to process-oriented and finally towards individualized patient care, also called personal care, based on ehealth platform services. Interoperability requirements for ubiquitous personalized health services reach beyond current concepts of health information integration among professional stakeholders and related Electronic Patient Records. Future personal health platforms particularly have to maintain semantic interoperability among systems u...
This book constitutes the refereed proceedings of the Second Asian Conference on Computing Science, ASIAN'96, held in Singapore in December 1996. The volume presents 31 revised full papers selected from a total of 169 submissions; also included are three invited papers and 14 posters. The papers are organized in topical sections on algorithms, constraints and logic programming, distributed systems, formal systems, networking and security, programming and systems, and specification and verification.
Without light there would be no life in the sea. Since the seas were the cradle for the evolution of all life forms, the theme of this book is central to our understanding of the interaction between living organisms and their environments. To express the breadth of research in this area, leading experts in topics as diverse as satellite imagery and molecular biology have contributed to this collection of essays on light and life in the sea, first published in 1990. Intended for all with an interest in the marine environment, this book aims to present the reader with a sampler of the exciting research that is underway and to provide an introduction to its broad compass.
Of Part A.- 1. Chemical Bonding and Molecular Structure.- 1.1. Valence-Bond Approach to Chemical Bonding.- 1.2. Bond Energies, Lengths, and Dipoles.- 1.3. Molecular Orbital Theory.- 1.4. Hückel Molecular Orbital Theory.- General References.- Problems.- 2. Stereochemical Principles.- 2.1. Enantiomeric Relationships.- 2.2. Diastereomeric Relationships.- 2.3. Dynamic Stereochemistry.- 2.4. Prochiral Relationships.- General References.- Problems.- 3. Conformational and Other Steric Effects.- 3.1. Steric Strain and Molecular Mechanics.- 3.2. Conformations of Acyclic Molecules.- 3.3. Conformations o.
This two-volume set LNAI 7523 and LNAI 7524 constitutes the refereed proceedings of the European Conference on Machine Learning and Knowledge Discovery in Databases: ECML PKDD 2012, held in Bristol, UK, in September 2012. The 105 revised research papers presented together with 5 invited talks were carefully reviewed and selected from 443 submissions. The final sections of the proceedings are devoted to Demo and Nectar papers. The Demo track includes 10 papers (from 19 submissions) and the Nectar track includes 4 papers (from 14 submissions). The papers grouped in topical sections on association rules and frequent patterns; Bayesian learning and graphical models; classification; dimensionalit...