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A história é contada a partir da visão de Laís Ferrero de Campos, uma jovem de dezessete anos que ao longo da sua jornada passará por algo terrível, desencadeando vários sentimentos adormecidos que ela nem sequer imaginava que poderia sentir — como a fúria, a desilusão e a mágoa —, mas a única forma de saná-los é simplesmente com o amor. Leitores, vamos descobrir juntos o que causou esses sentimentos horríveis na jovem Laís e se vocês reagiriam da mesma forma que ela.
In the monograph, recognition of the receptors by drugs is described as a complex phenomenon that has not been yet entirely understood. The description of molecular structure information necessary to achieve specific receptors without getting lost among huge amounts of non-specific acceptors is present. Various examples of receptor' binding features for narcotic analgetics, neuroleptics, tranquilisators, ligands of acetylcholine receptors are also included. The three stages of drug interaction with acceptors are considered, namely, distant stage, stage of orientation of the molecule on the acceptor, stage of molecule fixation. Kinetics and thermodynamics of these stages as well as factors preventing drug binding to non-specific acceptors are described. Some considerations concerning methods of changing activity and selectivity of drugs are given. Literature information needed for analysis of molecular mechanisms of interactions between drugs and receptors is present.
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This book gathers selected high-quality research papers presented at the Seventh International Congress on Information and Communication Technology, held at Brunel University, London, on February 21–24, 2022. It discusses emerging topics pertaining to information and communication technology (ICT) for managerial applications, e-governance, e-agriculture, e-education and computing technologies, the Internet of Things (IoT) and e-mining. Written by respected experts and researchers working on ICT, the book offers a valuable asset for young researchers involved in advanced studies. The work is presented in four volumes.