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Phenomenological Structure for the Large Deviation Principle in Time-Series Statistics
This thesis describes a method to control rare events in non-equilibrium systems by applying physical forces to those systems but without relying on numerical simulation techniques, such as copying rare events. In order to study this method, the book draws on the mathematical structure of equilibrium statistical mechanics, which connects large deviation functions with experimentally measureable thermodynamic functions. Referring to this specific structure as the “phenomenological structure for the large deviation principle”, the author subsequently extends it to time-series statistics that can be used to describe non-equilibrium physics. The book features pedagogical explanations and also shows many open problems to which the proposed method can be applied only to a limited extent. Beyond highlighting these challenging problems as a point of departure, it especially offers an effective means of description for rare events, which could become the next paradigm of non-equilibrium statistical mechanics.
An Introduction to Stochastic Thermodynamics
This book presents the fundamentals of stochastic thermodynamics, one of the most central subjects in non-equilibrium statistical mechanics. It also explores many recent advances, e.g., in information thermodynamics, the thermodynamic uncertainty relation, and the trade-off relation between efficiency and power. The content is divided into three main parts, the first of which introduces readers to fundamental topics in stochastic thermodynamics, e.g., the basics of stochastic processes, the fluctuation theorem and its variants, information thermodynamics, and large deviation theory. In turn, parts two and three explore advanced topics such as autonomous engines (engines not controlled extern...
Early Psychosis and Early Intervention: Clinical, Functional, and Cognitive Outcomes
Psychotic disorders are a group of severe mental disorders which affects 2-3% of the population and constitutes one of the leading causes of disability worldwide. Early intervention (EI) represents a major paradigm shift in psychiatric service and has been demonstrated to be effective in outcome improvement for first-episode psychosis (FEP) and at-risk mental state (ARMS). However, despite the promising findings, evidence has shown that a significant proportion of early psychosis patients still experience suboptimal clinical outcomes (such as high relapse risk, partial remission, early-onset treatment resistance, persistent negative symptoms, etc.), functional impairment and cognitive dysfun...
Early Intervention in Psychiatric Disorders Across Cultures
Evidence indicates a correlation between early intervention and improved response in psychiatric disorders. Yet the majority of evidence is from high-income countries, and there is a lack of evidence and resources on the impact of early intervention across cultures and in low- and middle-income countries. Early Intervention in Psychiatric Disorders across Cultures aims to bridge this gap by focusing on the evidence and methods of intervention in less affluent countries. It covers mood disorders, personality disorders, addictions, and other psychiatric conditions, whilst most research has focused on psychoses and bipolar disorder. Over 17 chapters, this resource guides the reader through an array of approaches to early intervention, from brain imaging and available care pathways, to cultural and societal factors. Part of the Oxford Cultural Psychiatry series, this resource offers readers a picture of the current health care pathways available as well as social, cultural, and ethical considerations to apply in practice.
Early Psychosis Intervention
Taking into account cultural differences between Asian and Western patients, this book focuses on delivery of effective treatment at an early stage in psychosis, especially for young people. It pays particular attention to early intervention programmes established in Hong Kong and Singapore, and assesses recent developments in Korea, Japan and other countries. The volume covers approaches in the management of psychosis, including pathway to care, stigma and interventions. With reference to the experiences of frontline practitioners, research findings and theories, it highlights the practical needs in non-Western healthcare settings. Culturally relevant discussions on recovery, relapse, self-harm and comorbid substance abuse are discussed. It also covers case studies to illustrate challenges and strategies in managing early psychosis.
Active Matter and Nonequilibrium Statistical Physics
From molecular motors to bacteria, from crawling cells to large animals, active entities are found at all scales in the biological world. Active matter encompasses systems whose individual constituents irreversibly dissipate energy to exert self-propelling forces on their environment. Over the past twenty years, scientists have managed to engineer synthetic active particles in the lab, paving the way towards smart active materials. This book gathers a pedagogical set of lecture notes that cover topics in nonequilibrium statistical mechanics and active matter. These lecture notes stem from the first summer school on Active Matter delivered at the Les Houches school of Physics. The lectures covered four main research directions: collective behaviours in active-matter systems, passive and active colloidal systems, biophysics and active matter, and nonequilibrium statistical physics--from passive to active.
