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e-Pedia: Game of Thrones (season 6)
This carefully crafted ebook is formatted for your eReader with a functional and detailed table of contents. The sixth season of the fantasy drama television series Game of Thrones premiered on HBO on April 24, 2016, and concluded on June 26, 2016. It consists of ten episodes, each of approximately 50–60 minutes, largely of original content not found in George R. R. Martin's A Song of Ice and Fire series. Some material is adapted from the upcoming sixth novel The Winds of Winter and the fourth and fifth novels, A Feast for Crows and A Dance with Dragons. The series was adapted for television by David Benioff and D. B. Weiss. HBO ordered the season on April 8, 2014, together with the fifth ...
Beta Thalassemia
Beta thalassemia is a common blood disorder worldwide. Thousands of infants with beta thalassemia are born each year. This book covers most of the aspects related to this disease and greatly helps in understanding this disease and its complications. Of interest are clinical studies as well as basic and translational research reports regarding pathogenesis, genetics, diagnosis as well as standard and novel therapies. This book intends to provide the reader with a comprehensive overview of today’s practices and tomorrow’s possibilities about beta thalassemia.
Thalassemia Syndromes
The thalassemia syndromes are a diverse group of hereditary anemias caused by decreased or absent production of one type of globin chain. Genetic counseling, prenatal diagnosis, and newborn screening are all issues of importance in these inherited disorders. This book provides a comprehensive overview of thalassemia, including information on its mechanisms and treatment modalities. Chapters elucidate the mechanism of disordered synthesis of hemoglobin in thalassemia and present recent studies of the genetic mechanisms that underlie this abnormal biosynthetic process.
Iron Metabolism
Iron is an essential element for numerous fundamental biologic processes. Iron-containing proteins are required for vital cellular and organismal functions including oxygen transport, mitochondrial respiration, intermediary and xenobiotic metabolism, nucleic acid replication and repair, host defense, and cell signaling. However, excess iron is toxic. This book provides a comprehensive overview of the essential role of iron in biology, the regulation of systemic and cellular iron homeostasis, and how imbalances in iron homeostasis contribute to disease.
Catechol-O-methyltransferase Val158Met Polymorphism and Hyperactivity Symptoms in Egyptian Children with Autism Spectrum Disorder
Catechol-O-methyltransferase (COMT) plays an important role in the catabolism of braindopamine and norepinephrine, which have been implicated in the pathogenesis of Autismspectrum disorder (ASD) as well as in other neuropsychatric disorders. We aimed toinvestigate the association of COMT Val158Met gene polymorphism with ASD and toexamine the influence of such genotypes on hyperactivity symptoms in ASD patients.Eighty ASD patients (mean age 9 u0002 1.9 years) and 100 control children (mean age 8.9 u0002 1.9years) were examined. COMT Val58Met polymorphism was genotyped using Tetra-primerARMS-PCR method. The clinical diagnosis of ASD and ADHD were confirmed according to theDSM-IV criteria for r...
Football Hooliganism, Fan Behaviour and Crime
Focusing on a number of contemporary research themes and placing them within the context of palpable changes that have occurred within football in recent years, this timely collection brings together essays about football, crime and fan behaviour from leading experts in the fields of criminology, law, sociology, psychology and cultural studies.
Neuroblastoma
Neuroblastoma (NBL) is the most common extracranial solid tumor of childhood, with about 700 new cases of neuroblastoma seen each year in the United States. The 5-year survival rate for children with high-risk NBL is only 50-60%, and this survival rate has not improved over the last 10 years. High-risk patients receive multimodality treatment, including chemotherapy, surgery, radiation therapy, biologic therapy and immunotherapy, all of which are associated with significant morbidity. Recent years have seen many advances in treatment of neuroblastoma, including therapeutic MIBG, immunotherapy, and personalized targeted therapy based on the genetic alterations seen in the tumor. The primary o...
Health Disparities
This uniquely accessible volume challenges professionals to understand—and help correct—health disparities, both at the patient level and in their larger social contexts. Dedicated to eradicating this ongoing injustice, contributors focus on marginalized populations, the role of healthcare systems in perpetuating inequities, the need for deeper engagement and listening by professionals, and the need for advocacy within professional education and the political/policy arena. The compelling case narratives at the core of the book illustrate the interrelated biopsychosocial components of patients’ health problems and the gradations of learning needed for practitioners to address them effec...
Downward Dog
“What Karl Lagerfeld is to fashion, Edward Vilga is to yoga. He has poured his years of experience into this sexy, charming and well-written escapade” (Simon Doonan, author of Soccer Style). A study in love, loss, and sexual misadventures in New York City, Downward Dog tells the tale of a handsome Bad Boy who becomes a yoga instructor while trying to redeem his womanizing ways and win the forgiveness of the only woman he’s ever really loved. Down on his luck thanks to a failed nightlife venture which fell apart because of his womanizing, our hero’s stuck with massive debt and broken dreams. His only safe haven is the yoga world, and when his well-connected best buddy launches his yoga career among NYC’s elite, our working class hero becomes a guru to society’s top 1%, a wolf let loose amongst a flock of comely sheep. “Downward Dog is not only a sexy/funny page turner, it also shares the emotional journey of one Bad Boy’s transformation and romantic redemption.” —Chip Conley, New York Times–bestselling author of Peak
Complementary Feeding: Building the Foundations for a Healthy Life
The complementary feeding period from 6 to 24 months is a crucial part of the first 1000 days of development. It marks the transition from exclusively milk-based liquid diet to the family diet and self-feeding. During this period, healthy food preferences and feeding practices are formed. The papers in this book were presented at the 87th Nestlé Nutrition Institute Workshop in Singapore, May 2016. Divided into three parts, they provide updates and recommendations, as well as insights into strategies and interventions, from all around the world. The first part addresses the role of complementary feeding in healthy development, focusing on food types and the timing of solid food introduction. The second part examines determinants of growth restriction and discusses effective interventions in infants and children in low- and middle-income countries. The last part focuses on development and 'programming' of behavioral and psychological aspects to prevent childhood obesity in high socioeconomic settings.
