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Basic and clinical aspects are discussed by expert contributors in this book devoted to stimulating further studies and developing new therapies for pulmonary fibrosis. Current laboratory and basic findings are reviewed in the book's first 19 chapters, while clinical aspects are addressed in the remaining 16 chapters. These aspects include laboratory and bronchalveolar findings, diagnosis, treatment and prognosis of idiopathic pulmonary fibrosis, collagen disease lungs, sarcoidosis, pneumoconiosis, hypersensitive pneumonia, drug-induced pneumonia, ARDS, radiation pneumonia, BOOP, viral pneumonia, and other diseases causing pulmonary fibrosis. The roles of various cytokines, viral infection, and lung injuries in the development and pathogenesis of pulmonary fibrosis are discussed. The definition, classification, and lung functions of pulmonary fibrosis are included as well.
This book provides a comprehensive, authoritative, and contemporary discussion of the physiology and pathophysiology of the chest wall as well as an overview of the diagnostic and therapeutic modalities. It is an invaluable aid to clinical investigators.
"Analyzes the role of peptides in promoting or suppressing inflammation. Thoroughly examines the therapeutic potential of key peptides, analogs, agonists, and antagonists that influence cell injury and repair."
Synthesizing disparate information into a readily accessible format, this insightful volume presents state-of-the-art reviews on the basic and clinical features of pulmonary diseases in HIV-infected individuals-informing critical decision making as well as suggesting avenues for future research. A beneficial compendium for those dealing with pulmonary complications of HIV infection, Human Immunodeficiency Virus and the Lung surveys current knowledge on the epidemiology of HIV infection examines HIV's effects on lung cells in addition to immune functions within the lung details individual pulmonary infections in terms of etiology, clinical presentation, diagnosis, treatment, and prophylaxis emphasizes the indications and limitations of various diagnostic techniques, including invasive and noninvasive testing and screening considers noninfectious pulmonary complications from neoplastic and inflammatory to immunological disorders advises on the management of individuals in intensive care with the aid of morbidity and mortality data assesses common recommendations as well as provides clear guidelines for preventing the transmission of infectious pathogens and more!
Reflects the explosion of information and technological breakthroughs that have facilitated investigations into the development of the lung-including recombinant DNA technology, molecular genetics, transgenics, and advances in lung cell and mo-lecular biology. Provides nearly 2800 bibliographic citations and over 170 tables, drawings, and x-rays to help clarify specific discussions.
This state-of-the-art reference outlines current knowledge of the structure, transcriptional regulation, and binding characteristics of vascular and leukocyte adhesion molecules and their ligands delineating the nature of adhesion molecule interactions in lung morphogenesis and repair, tumor metastasis, and experimental models of inflammatory lung injury.
This work sets out to provide the information necessary for understanding endotoxin and its effects on the lungs, and explicates the difficulties in determining how to manipulate endotoxin pathobiology. The rationale for, and efficacy of, current and experimental treatments for sepsis, adult respiratory distress syndrome and other endotoxin-induced lung injuries are discussed.
Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.
This unique reference integrates the theory and practical use of aerosols in inhalation therapy into a single resource-presenting the physical chemistry of formulation, the physics of aerosol generation, aerodynamic behavior, and therapeutic implications. Offers up-to-date techniques for droplet and particle generation, including air-blast and ultrasonic nebulizers, propellant-driven metered-dose inhalers, dry-powder inhalers, and elecctrospray systems!