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Base Excision Repair Pathway
This detailed volume provides a comprehensive set of experimental protocols and useful strategies to examine the repair of damaged bases via the Base Excision Repair (BER) pathway in vitro and in cells. Beginning with multiple molecular and cellular techniques to examine the excision of damaged bases from double-stranded DNA or DNA wrapped in a nucleosome, the book continues with sections covering procedures to detect and quantify the damaged bases, protein DNA crosslinks, and double-strand breaks, experimental procedures to identify DNA repair protein interactome by conventional tandem affinity purification followed by mass spectroscopy analysis, as well as the analysis of genome-wide bindi...
Mechanisms of DNA Repair
Mechanisms of DNA Repair.
DNA Repair, Part A
DNA Repair, Part A provides detailed coverage of modern methods for molecular analysis of enzymes and enzyme systems that function in the maintenance of genome integrity. Coverage areas include base excision repair, nucleotide excision repair, translesion DNA polymerases, mismatch repair, genetic recombination, and double strand break repair. A laboratory standard for more than 40 years Over 400 volumes strong Also available on ScienceDirect Part A of a 2-part series
Progress in Nucleic Acid Research and Molecular Biology
This is a cumulative subject index for volumes 40-72 of Progress in Nucleic Acid Research and Molecular Biology. This series is intended to bring to light the most recent advances in these overlapping disciplines with a timely compilation of reviews comprising each volume. Cumulative subject index for volumes 40-72 of Progress in Nucleic Acid Research and Molecular Biology. Brings to light the most recent advances in these overlapping disciplines with a timely compilation of reviews comprising each volume.
The Good, The Bad and The Ugly: Multiple Roles of Bacteria in Human Life
Bacteria are among the earliest forms of life on Earth. Notwithstanding their small size and primitive origin, bacteria still have a tremendous impact on everyday human life. Over the centuries, research into bacteria have provided and enriched the fundamental biological knowledge due to their readily measured processes and effects on higher organisms. Although molecular genetics and microbiology were among the scientific fields that have mostly benefited from the discoveries made in bacteria, our current state of knowledge has gone beyond what anyone could have ever imagined. The present Research Topic aims to cover new and exciting broad aspects of the importance of bacteria to human life,...
Asthma
This volume details a collection of laboratory protocols to study asthma in mice and humans. Chapters cover animal models of asthma, methods to measure asthma-related molecules, protocols to detect, isolate, culture and stimulate cells that contribute to asthma in mice and humans, methods to deplete these cells in vivo and study responses of intact airway tissues ex vivo. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Asthma: Methods and Protocols aims to be a foundation for future studies and to be a source of inspiration for new investigations in the field.
DNA Damage Recognition
Stands as the most comprehensive guide to the subject-covering every essential topic related to DNA damage identification and repair. Covering a wide array of topics from bacteria to human cells, this book summarizes recent developments in DNA damage repair and recognition while providing timely reviews on the molecular mechanisms employe
RNA Polymerase and Associated Factors
RNA polymerase is molecule important to gene transcription. Along with associated factors, RNA polymerase is part of the process in which RNA is transcribed to produce a protein. * Models and methods for studying polymerase translocation * Assay for movements of RNA polymerase along DNA * Engineering of elongation complexes of bacterial and yeast RNA polymerases
Separation Methods In Microanalytical Systems
Focusing on what has been one of the driving forces behind the development of lab-on-a-chip devices, Separation Methods in Microanalytical Systems explores the implementation, realization, and operation of separation techniques and related complex workflows on microfabricated devices. The book details the design, manufacture, and integration of diverse components needed to perform an entire analytical procedure on a single miniaturized device. This volume is valuable reference for scientists and engineers anticipating the demand for function-specific chemical separation systems in biomedical diagnostics, environmental monitoring, and drug discovery applications.
Diabetes Mellitus Epidemic, Combat the Challenge
Contributed articles presented at the fourth International Seminar of Asian Network of Research on Antidiabetic Plants.
