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In April 2000 researchers from around the world met in Lexington, Kentucky to bring together the very latest information on the chemistry and biological effects of the environmental pollutants known as Polychlorinated Biphenyls (PCBs). The result is a comprehensive and extensive treatment of the very latest findings on all significant subjects relating to PCBs and their health risks. The thorough introduction and sixty-two scientific papers presented here represent the most up-to-date research by scientists in government, private industry, and academia.
Neurobiology of PTSD outlines the basic neural mechanisms that mediate complex responses and adaptations to psychological trauma; describes how these biological processes are impaired in individuals with posttraumatic stress disorder (PTSD); and discusses how the environmental exposure to trauma interacts with the brain to create the syndrome of PTSD.
Na+-K+ ATPase or Na-pump ATPase, a member of “P”-type ATPase superfamily, is characterized by association of multiple isoforms mainly of it’s α- and β- subunits. At present four different α- (α-1,α-2,α-3 and α-4) and three β- (β-1, β-2, and β-3) isoforms have been identified in mammalian cells and their differential expressions are tissue specific. Regulation of Na+-K+ ATPase activity is an important but a complex process, which involves short-term and long-term mechanisms. Short-term regulation of Na+-K+ ATPase is either mediated by changes in intracellular Na+ concentrations that directly affect the Na+-pump activity or by phosphorylation/dephosphorylation-mediated by some...