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Correlated neuronal activity and its relationship to coding, dynamics and network architecture
Correlated activity in populations of neurons has been observed in many brain regions and plays a central role in cortical coding, attention, and network dynamics. Accurately quantifying neuronal correlations presents several difficulties. For example, despite recent advances in multicellular recording techniques, the number of neurons from which spiking activity can be simultaneously recorded remains orders magnitude smaller than the size of local networks. In addition, there is a lack of consensus on the distribution of pairwise spike cross correlations obtained in extracellular multi-unit recordings. These challenges highlight the need for theoretical and computational approaches to understand how correlations emerge and to decipher their functional role in the brain.
The Role of Synaptic Tagging and Capture for Memory Dynamics in Spiking Neural Networks
Memory serves to process and store information about experiences such that this information can be used in future situations. The transfer from transient storage into long-term memory, which retains information for hours, days, and even years, is called consolidation. In brains, information is primarily stored via alteration of synapses, so-called synaptic plasticity. While these changes are at first in a transient early phase, they can be transferred to a late phase, meaning that they become stabilized over the course of several hours. This stabilization has been explained by so-called synaptic tagging and capture (STC) mechanisms. To store and recall memory representations, emergent dynami...
Statistical analysis of multi-cell recordings: linking population coding models to experimental data
Modern recording techniques such as multi-electrode arrays and 2-photon imaging are capable of simultaneously monitoring the activity of large neuronal ensembles at single cell resolution. This makes it possible to study the dynamics of neural populations of considerable size, and to gain insights into their computations and functional organization. The key challenge with multi-electrode recordings is their high-dimensional nature. Understanding this kind of data requires powerful statistical techniques for capturing the structure of the neural population responses and their relation with external stimuli or behavioral observations. Contributions to this Research Topic should advance statist...
The Spike
The story of a neural impulse and what it reveals about how our brains work We see the last cookie in the box and think, can I take that? We reach a hand out. In the 2.1 seconds that this impulse travels through our brain, billions of neurons communicate with one another, sending blips of voltage through our sensory and motor regions. Neuroscientists call these blips “spikes.” Spikes enable us to do everything: talk, eat, run, see, plan, and decide. In The Spike, Mark Humphries takes readers on the epic journey of a spike through a single, brief reaction. In vivid language, Humphries tells the story of what happens in our brain, what we know about spikes, and what we still have left to u...
Blue Machine
SHORTLISTED FOR THE 2024 WAINWRIGHT PRIZE FINANCIAL TIMES 2023 HIGHLIGHT 'Helen Czerski weaves together physics and biology, history and science, in a beautifully poetic way.' Professor Alice Roberts 'In Helen Czerski's hands, the mechanical becomes magical. An instant classic.' Tristan Gooley, author of How to Read Water 'Blue Machine is quite simply one of the best books I have ever read.' Dr George McGavin, zoologist, entomologist and broadcaster 'A fascinating dive into the essential engine that drives our world. Czerski brings the oceans alive with compelling stories that masterfully navigate this most complex system.' Gaia Vince, science journalist, broadcaster and author of Nomad Cent...
A History of Bodies, Brains, and Minds
A panoramic view of the evolution of life on our planet, from its origins to humanity’s future. In A History of Bodies, Brains, and Minds, Francisco Aboitiz provides a brief history of life, the brain, and cognition, from the earliest living beings to our own species. The author proceeds from the basic premise that, since evolution by natural selection is the process underlying the origin of life and its evolution on earth, the brain—and thus our minds—must also be the result of biological evolution. The aim of this book is to narrate how animal bodies came to be built with their nervous systems and how our species evolved with culture, technology, language, and consciousness. The book...
Was MusiktherapeutInnen über das Gehirn wissen sollten
Was spielt sich im Gehirn ab, wenn Musik gespielt wird? Wie wirken Töne auf den (Muskel-) Tonus? Was hat die Stimme mit der Stimmung zu tun? Solche Fragen zu Grundlagen der Neurobiologie von Musik und Musiktherapie werden in diesem Buch beantwortet - didaktisch aufbereitet mit vielen praktischen Beispielen und Abbildungen. Ausgehend von den neuroanatomischen und -physiologischen Grundlagen werden das Hören allgemein sowie speziell die Perzeption und Produktion von Musik anschaulich erklärt. Anhand ausgewählter klinischer Störungsbilder aus Psychiatrie und Neurologie werden neurobiologische Modelle zur Wirksamkeit von Musiktherapie diskutiert. Ein unverzichtbares Kurz-Lehrbuch und Nachschlagewerk für alle, die sich für die Musikwirkung auf Psyche und Körper interessieren.
스파이크
시스템 신경과학 연구의 세계적 석학 마크 험프리스가 신경계의 본질적 요소 ‘스파이크’의 여행을 따라가며 그 작용을 낱낱이 살펴본 책 《스파이크》가 출간되었다. 우리가 다채로운 정신적 능력을 누리고 신체를 세심히 움직일 수 있는 것은 모두 뇌 속 뉴런들이 정보를 주고받는 수단인 스파이크 덕분이다. 하지만 우리는 극히 최근에서야 스파이크들을 동시에 기록하고 그것들이 어디로 전송되는지 정확히 알아내기 시작했다. 이른바 ‘시스템 신경과학의 황금시대’가 도래한 것이다. 이 책은 시스템 신경과학의 기술적...
블루 머신
해양물리학을 중심으로 자연사와 지리학, 역사와 문화를 넘나들며 바다의 움직임을 추적한 최고의 대중 과학서! “바다는 그 어떤 과학보다 내가 인간이라는 사실을 상기시킨다.” 이 책의 저자 헬렌 체르스키는 BBC를 대표하는 과학 다큐멘터리 진행자이자 칼럼니스트로, 수백만 청중에게 일상 속 물리학의 아름다움을 전하며 저명한 해양과학자로 입지를 다졌다. ‘블루 머신’은 지구 전체를 순환하며 세계의 균형을 조율하는 바다를 거대한 엔진으로 묘사하며 헬렌 체르스키가 붙인 말이다. 이 푸른 기계의 정교한 움직임 덕...
