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Genetics and Molecular Biology of Anaerobic Bacteria
The field of bacterial genetics has been restricted for many years to Escherichia coli and a few other genera of aerobic or facultatively anaerobic bacteria such as Pseudomonas, Bacillus, and Salmonella. The prevailing view up to recent times has been that anaerobic bacteria are interesting organisms but nothing is known about their genetics. To most microbiologists, anaerobic bacteria appeared as a sort of distant domain, reserved for occasional intrusions by taxonomists and medical microbiologists. By the mid-1970s, knowledge of the genetics and molecular biology of anaerobes began to emerge, and then developed rapidly. but also im This was the result of advances in molecular biology techn...
The Army List
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On Every Play Eleven Men Believed
"The eleven men who lined up on every play for the St. Louis Rams knew something the rest of the world did not. Something the fans thought would take a miracle. Something the sportscasters and odds-makers doubted. Something the other NFL teams, at least at the beginning of the season, considered impossible. But the players and coaches of the 1999-2000 St. Louis Rams shared one common mission: to win the Super Bowl. They showed up for work every day, they did their jobs and did them well. They believed in something almost no one else did. Themselves. They worked through adversity and trusted in their teammates to step up when it counted most. Week in and week out, the Rams executed their plan...
Handbook of Natural Toxins
This volume describes the structure and function of bacterial toxins and presents a comprehensive review of virulence factors, providing recent information concerning cell physiology and biochemistry, as well as new toxin tools for experimental studies and clinical therapy. A wide variety of toxic proteins, including the toxins that cause diptheria, cholera, pertussis, shigellosis, tetanus, botulism and anthrax, are discussed.;The work is aimed at microbiologists, biochemists, endocrinologists, toxicologists, infectious disease specialists, pathologists, public health officials, and upper-level undergraduate and graduate students in these disciplines.
Human Health
Human Health: The Contribution of Microorganisms is the first major work to concentrate on probiotics in humans. It presents both new and established data on the origins and importance of commensal floras, the history and characteristics of probiotics, the use of probiotics in clinical situations, and preclinical and volunteer studies. It also covers commercial issues such as the difficulties involved in the large scale production and formulation of live microorganisms, and the marketing techniques used to sell products containing bacteria. It contains contributions from internationally recognised experts in both science and industry. Written with both professional and lay audiences in mind, Human Health: The Contribution of Microorganisms will be an indispensable text and reference source for scientists, clinicians, and pharmaceutical/food technologists.
Special Issue on Emerging Bacterial Toxins
With contributions by numerous experts
Human Intestinal Microflora in Health and Disease
Human Intestinal Microflora in Health and Disease deals with human indigenous intestinal flora, the vast assemblage of microorganisms that reside in the intestinal tract. It contains information on the composition of the flora, its development, metabolic activities, importance to the host, and the consequences of upsetting its ecology. The book is organized into four parts. Part I examines the composition and development of intestinal flora. Part II deals with the metabolic activities of intestinal microflora. These include studies on carbohydrate metabolism in the human colon; the compounds used as nitrogen sources by gastrointestinal tract bacteria; and metabolic transformations of xenobio...
Enteric Infections and Immunity
As we approach the end of this millennium, enteric diseases remain impor tant public health problems. In many parts of the world, sanitary measures have advanced little over the last century, although some of the governments in those areas are striving to improve facilities for sanitation and to educate their people in proper handling of food, water, sewage, and other modes of transmission of pathogenic microbes. Even in highly developed countries, outbreaks of diarrheal diseases occur today. Globally, the annual morbidity from enteric infections is estimated at several billion and deaths at several million per year. In this volume, descriptions of some of these diseases, of immunity that re...
Clostridioides difficile
The book provides a comprehensive overview of the current knowledge about Clostridioides (C.) difficile (formerly known as Clostridium difficile) and Clostridioides difficile infections (CDI). The diseases caused by C. difficile range from mild diarrhea to fulminant and in some cases fatal colitis. Historically, CDI was considered mainly as a hospital-acquired problem. Today, a significant portion of CDI is community acquired. Triggered by the introduction of new antibiotics, hypervirulent and multi-drug resistant strains of C. difficile (e.g., C. difficile ribotype R027) have emerged and spread across the globe. The volume covers the microbiology, pathophysiology, epidemiology, risk factors...
Bacterial Protein Toxins
In recent years remarkable progress has been accomplished with respect to our knowledge about bacterial protein toxins. This refers especially to structural aspects of protein toxins but also holds true for genetics, molecular biology and biochemical mechanisms underlying the action of toxins. This volume covers the very current and exciting aspects of up-to-date bacterial toxicology and comprehensively reviews the most important bacterial protein toxins such as the intracellular acting toxins which exhibit enzyme activity, as well as those toxins that interact with cell plasma membranes by damaging the membranes (pore formation) or stimulating cell receptors (superantigens). This is the most current reference work on these important bacterial protein toxins, which are presented from the point of view of different disciplines such as pharmacology, microbiology, cell biology and protein chemistry.
