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Central nervous system trauma, which encompasses stroke, subarachnoid hemorrhage, head injury, and spinal cord injury, is a leading cause of death in developed countries. In the search for underlying mechanisms, membrane involvement has been the common link. This fourth volume in the Membrane-Linked Diseases series is therefore dedicated to research on CNS trauma. Focusing on the mechanism of membrane damage, Central Nervous System Trauma: Research Techniques presents a variety of experimental techniques to study the mechanism of CNS trauma. Animal and tissue culture models provide the bulk of the research findings in this area. Possible pharmacological interventions are analyzed. This volume offers numerous illustrative examples, including full color figures. This book serves as a valuable resource for students and researchers, assisting in the comprehension of current trends in CNS trauma and helping to stimulate the discovery of new research areas.
The comparison of MR images and cadaver microangiograms of the basal perforating arteries is crucial for understanding the courses and supply areas of these vessels and in turn, for diagnosing pathologies in this region. Divided into three sections- normal anatomy of brain vessels; neurovascular imaging in pathology; and anatomy and imaging of spinal vessels- Neurovascular Imaging contains a rich collection of images to teach the reader how to interpret MR images of the brain vessels and spinal vessels, and how to identify pathological signs. Written and edited by a group of highly acclaimed experts in the field, Neurovascular Imaging is an authoritative account of the interpretation of MR images of the brain vessels and spinal vessels, and is a valuable addition to the library of the diagnostic radiologist.
Introducing The Smartbook of Neurosurgery , a concise, informative, useful and evidence based guide for residents, young neurosurgeons and health care professional interested in neurosurgery. This book has been done thinking about the most common challenging situations and questions that come during the daily activities as a resident or young neurosurgeon. This book contains over 2,000 questions divided in 8 chapters and these chapters include basic, translational, clinical and surgical scenarios The question and answer for the topics Neuroanatomy, Neurophysiology, Neuropharmacology, Neuroradiology, cranial and brain surgery, Neuroradiology, Neuropathology, Neurology, Pediatric Neurosurgery, Spine Surgery, Peripheral Nerve, Tips and Tricks on the cranial approach, intracranial tumor neurosurgery, endoscopic neurosurgery, cerebrovascular surgery and cranial trauma neurosurgery are clearly defined as Smartbook of Neurosugery. This book represents a resource for on-the fly consults in a busy hospital day, as a refresher for boards and to prepare medical students for their neurosurgical rotations or before getting into the residency.
This fascinating monograph is filled with information formerly found only in periodicals and symposia proceedings. Chapters discuss the different models of cerebral ischemia in use today, including their advantages and disadvantages. This one-of-a-kind resource also contains essential chapters on cellular mechanisms of ion and acid-base homeostases, and energy metabolism of the ischemic brain. It reviews the possible role of lipids, free fatty acids, and free radicals. Four chapters are devoted to neurotransmitters and neuroregulators in cerebral ischemia. This extraordinary work also covers aspects of protection against and resuscitation from cerebral ischemia. An extremely informative volume, this book is an absolute must for every student in the field of cerebral ischemia, as well as the clinician or scientist who is already involved with this worldwide problem.
Schmidek and Sweet has been an indispensable reference for neurosurgery training and practice for nearly 50 years, and the 7th Edition of Operative Neurosurgical Techniques continues this tradition of excellence. A new editorial board led by editor-in-chief Dr. Alfredo Quinones-Hinojosa, along with more than 330 internationally acclaimed contributors, ensures that readers stay fully up to date with rapid changes in the field. New chapters, surgical videos, and quick-reference features throughout make this edition a must-have resource for expert procedural guidance for today's practitioners. - Discusses indications, operative techniques, complications, and results for nearly every routine and...
Despite numerous recent studies and exciting discoveries in the field, only limited treatment is available today for the victims of acute neurological injuries. Animal Models of Acute Neurological Injuries provides a standardized methodology manual designed to eliminate the inconsistent preparations and variability that currently jeopardizes advances in the field. Contributed by top experts and many original developers of the models, each chapter contains a step-by-step, proven procedure and visual aids covering the most commonly used animal models of neurological injury in order to highlight the practical applications of animal models rather than the theoretical issues. This intensive volume presents its readily reproducible protocols with great clarity and consistency to best aid neuroscientists and neurobiologists in laboratory testing and experimentation. Comprehensive and cutting-edge, Animal Models of Acute Neurological Injuries is an ideal guide for scientists and researchers who wish to pursue this vital course of study with the proficiency and precision that the field requires.
This book provides the first comprehensive account of multilineage-differentiating stress-enduring (Muse) cells, a pluripotent and non-tumorigenic subpopulation of mesenchymal stem cells (MSCs) that have the ability to detect damage signals, migrate to damaged sites, and spontaneously differentiate into cells compatible with the affected tissue, thereby enabling repair of all tissue types. The coverage encompasses everything from the basic properties of Muse cells to their tissue repair effects and potential clinical applications—for example, in acute myocardial infarction, stroke, skin injuries and ulcers, renal failure, and liver disease. An important technical chapter provides a practical and precise protocol for the isolation of Muse cells, which will enable readers to use Muse cells in their own research. In offering fascinating insights into the strategic organization of the body’s reparative function and explaining how full utilization of Muse cells may significantly enhance the effectiveness of MSC treatment, the book will be of high value for Ph.D. students, postdocs, basic researchers, clinical doctors, and industrial developers.
As MRI has paved its role in diagnostic angiography. MRA has the potential to provide more physiological and pathophysiological data over the disease in addition to the anatomical information. This book is divided into three sections. The first section discusses the basics of MRI angiography. It starts with focus on the contrast agents that are mainly used in MR angiography with detailed discussion of advantage and limitations of different types of contrast. The second chapter is oriented more towards the technical consideration that contribute to good quality examination, both the non contrast and contrast based sequences from black to bright blood imaging , contrast enhanced MRA, review of...
This is an open access proceeding book of 9th European-Japanese Cerebrovascular Congress at Milan 2018. Since many experts from Europe and Japan had very important and fruitful discussion on the management of Cerebrovascular diseases, the proceeding book is very attractive for the physician and scientists of the area.
86 short papers originating from the 13th International Symposium on Intracranial Pressure and Brain Monitoring held in July 2007 in San Francisco present experimental as well as clinical research data on invasive and non-invasive intracranial pressure and brain biochemistry monitoring. The papers have undergone a peer-reviewing and are organized in eight sections: brain injury: ICP management and cerebral physiology; hydrocephalus and cerebrospinal fluid dynamics; advanced neuromonitoring; biomedical informatics; imaging; ICP: brain compliance, biophysics, and biomechanics; stroke, subarachnoid hemorrhage, and intracerebral hematoma; and experimental studies and models. The papers address the increasing use of decompressive craniectomy for the treatment of brain edema as well after brain injury and the rapidly expanding field of advanced neuromonitoring and neuroimaging.