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Frontiers in Radiation Oncology
The mode of action by radiation is postulated to be the production of double strand breaks of DNA. The repair of double strand breaks occurs through non homologous end joining through acetylation of histone proteins by histone acetyltransferases (HATs). The fixation of double strand breaks through HAT inhibitors is a promising application for radiation sensitization in the clinic. P53 is a tumour suppressor gene and its mutation has been implicated in 60% of human cancers. As one of the pivotal anticancer genes, P53 controls the transcription and translation of a series of genes. The kinetics of DNA double strand break generation and their co relation to P53 status, ATM and ARF activation are computed and modelled for understanding the potential of such research.
Translational Radiation Oncology
Translational Radiation Oncology covers the principles of evidence-based medicine and applies them to the design of translational research. The book provides valuable discussions on the critical appraisal of published studies and recent developments in radiation oncology, allowing readers to learn how to evaluate the quality of such studies with respect to measuring outcomes and make effective use of all types of evidence. By reading this book, researchers have access to a practical approach to help them navigate challenging considerations in study design and implementation. It is a valuable resource for researchers, oncologists and members of biomedical field who want to understand more abo...
Hospitals Around the World
The book constitutes easy reference for Hospitals, Nursing Homes, Clinics, Medical Publishers Around the World
Principles and Management of Cancer
Principles and Management of Cancer provides oncologists with the latest information on modern techniques for the treatment of various cancers. The book covers emerging technologies and new research in oncology, ensuring it is fully up to date with the latest advances in the field. Comprised of 25 chapters, topics range from lasers in head and neck cancers, to central nervous system and eye tumours. Chapters on soft tissue sarcoma, radiation pathology, emergencies in oncology, and paediatric tumours feature information on emerging technologies in these areas. With full colour images and illustrations throughout, Principles and Management of Cancer is a comprehensive resource covering everything from imaging, emergencies and nutrition, to new drug discoveries and clinical trials. Key Points Comprehensive resource on cancer, with the latest on current developments in the field Focuses on new research and technologies Full colour images and illustrations throughout
Accelerated Partial Breast Irradiation
Accelerated partial breast irradiation (APBI) is being rapidly introduced into the clinical management of early breast cancer. APBI, in fact, encompasses a number of different techniques and approaches that include brachytherapy, intraoperative, and external beam techniques. There is currently no single source that describes these techniques and their clinical implementation. This text is a concise handbook designed to assist the clinician in the implementation of APBI. This includes a review of the principles that underlie APBI, a practical and detailed description of each technique for APBI, a review of current clinical results of APBI, and a review of the incidence and management of treatment related complications.
Proton Therapy
Over the past twenty-five years, proton therapy has become more prominent worldwide. It is an important component of clinical radiation therapy for both adult and pediatric clinical care. Due to the inherent ability of protons to spare normal tissue, protons will continue to develop and become increasingly important in radiation oncology. As such, Proton Therapy - Current Status and Future Directions reviews many aspects of proton care including the application of protons in modern clinical trials. It also reviews problems associated with the migration of proton care worldwide and examines the future direction of proton care. This project was created by colleagues at IntechOpen and was caref...
Advances in Animal Disease Diagnosis
Advances in Animal Disease Diagnosis: Infectious animal diseases caused by pathogenic microorganisms such as bacteria, fungi, and viruses threaten the health and well-being of wildlife, livestock and human populations, limit productivity and significantly increase economic losses to each sector. Pathogen de-tection is an important step for the diagnosis and successful treatment of animal diseases as well as control management in farm and field conditions. The conventional techniques employed to diagnose pathogens in livestock species are time-consuming and sometimes give inconclusive results. On the contrary, molecular techniques have the potential to diag-nose known pathogens/conditions qui...
Industrial Enzymes
Leading experts in the enzymology field present herewith an overview of the use of enzymes in therapy, genetic engineering, pulp and paper, textile, detergent, food and animal feed. The book carries up to date information and presents a wider perspective scope wise in the field of enzymology. The book would be advantageous not only for Undergraduate, PG and PhD students but also to non-specialists who may acquaint themselves with this rapidly growing field. We feel extremely proud in recommending this book as ideal reading for any of the above students engaged in basic and applied research. Any library, industrial and academic platforms strongly suits this book as it is a very relevant in-de...
