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Selected Works of Terry Speed
The purpose of this volume is to provide an overview of Terry Speed’s contributions to statistics and beyond. Each of the fifteen chapters concerns a particular area of research and consists of a commentary by a subject-matter expert and selection of representative papers. The chapters, organized more or less chronologically in terms of Terry’s career, encompass a wide variety of mathematical and statistical domains, along with their application to biology and medicine. Accordingly, earlier chapters tend to be more theoretical, covering some algebra and probability theory, while later chapters concern more recent work in genetics and genomics. The chapters also span continents and generations, as they present research done over four decades, while crisscrossing the globe. The commentaries provide insight into Terry’s contributions to a particular area of research, by summarizing his work and describing its historical and scientific context, motivation, and impact. In addition to shedding light on Terry’s scientific achievements, the commentaries reveal endearing aspects of his personality, such as his intellectual curiosity, energy, humor, and generosity.
Statistical Analysis of Gene Expression Microarray Data
Although less than a decade old, the field of microarray data analysis is now thriving and growing at a remarkable pace. Biologists, geneticists, and computer scientists as well as statisticians all need an accessible, systematic treatment of the techniques used for analyzing the vast amounts of data generated by large-scale gene expression studies
Stat Labs
Integrating the theory and practice of statistics through a series of case studies, each lab introduces a problem, provides some scientific background, suggests investigations for the data, and provides a summary of the theory used in each case. Aimed at upper-division students.
The Mind's Arrows
This title provides an introduction to assumptions, algorithms, and techniques of causal Bayes nets and graphical causal models in the context of psychological examples. It demonstrates their potential as a powerful tool for guiding experimental inquiry.
I Thought He was a Speed Bump-- and Other Excuses from Life in the Fast Lane
"Most people in this country hurry too much. I know, because I have been one of them. For much of my adult life, I've broken dozens of glasses and plates each year whipping them in and out of the dishwasher, thinking all the while,'Get it done, get it done.' So begins this collection of reader-favorite columns, with its varied chapter headings ("Latin For the Not Yet Dead," "Fruit of The Loom Jesus" and "When Will Dad Become a Woman?") all centered around what kids have to teach us: about not driving so fast that we hardly know what - or, in the story which gives the book its title - who are driving over. "A delightful valentine to dispel the humdrum quality of everyday experience, Marotta's observations are rife with gentle wit and an enviable wisdom." The Boston Globe "At last: a book for frazzled people everywhere.... Full of faith hope and heart." The Cape Cod Times "Marotta's words pop out at you like those 3-D castles in a child's book." The Palm Beach Post I laughed and cried. It brought me a sense of connectedness and joy; It made my soul sing! - A reader in Vermont.
Making Sense of Complexity
On April 26-28, 2001, the Board on Mathematical Sciences and Their Applications (BMSA) and the Board on Life Sciences of the National Research Council cosponsored a workshop on the dynamical modeling of complex biomedical systems. The workshop's goal was to identify some open research questions in the mathematical sciences whose solution would contribute to important unsolved problems in three general areas of the biomedical sciences: disease states, cellular processes, and neuroscience. The workshop drew a diverse group of over 80 researchers, who engaged in lively discussions. To convey the workshop's excitement more broadly, and to help more mathematical scientists become familiar with these very fertile interface areas, the BMSA appointed one of its members, George Casella, of the University of Florida, as rapporteur. He developed this summary with the help of two colleagues from his university, Rongling Wu and Sam S. Wu, assisted by Scott Weidman, BMSA director. This summary represents the viewpoint of its authors only and should not be taken as a consensus report of the BMSA or of the National Research Council.
Algebraic Combinatorics and Computer Science
This book, dedicated to the memory of Gian-Carlo Rota, is the result of a collaborative effort by his friends, students and admirers. Rota was one of the great thinkers of our times, innovator in both mathematics and phenomenology. I feel moved, yet touched by a sense of sadness, in presenting this volume of work, despite the fear that I may be unworthy of the task that befalls me. Rota, both the scientist and the man, was marked by a generosity that knew no bounds. His ideas opened wide the horizons of fields of research, permitting an astonishing number of students from all over the globe to become enthusiastically involved. The contagious energy with which he demonstrated his tremendous m...
Understanding Lipid Metabolism with Microarrays and Other Omic Approaches
Reviewing current studies and previously unpublished research from leading laboratories around the world, Unravelling Lipid Metabolism With Microarrays demonstrates the use of microarrays and transcriptomic approaches to clarify the biological function of lipids. It provides an extensive overview of statistical approaches to microarray data, as well as discussions on how microarrays can be used to understand the role of lipids in the initiation or prevention of disorders such as cancer, diabetes, and obesity. Of particular note is a chapter by the only group known to study the effect of lipids on transcriptomics in multiple brain regions.
