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Neurochemistry is a flourishing academic field that contributes to our understanding of molecular, cellular and medical neurobiology. As a scientific discipline, neurochemistry studies the role of chemicals that build the nervous system, it explores the function of neurons and glial cells in health and disease, it discovers aspects of cell metabolism and neurotransmission, and it reveals how degenerative processes are at work in the nervous system. Accordingly, this book contains chapters from a variety of topics that fall into the following broad sections: I. Neural Membranes and Intracellular Signaling, II. Neural Processing and Intercellular Signaling, III. Growth, Development and Differe...
Histology is the science of tissues and as such histology studies cells and tissues of organs using a variety of techniques. Histological techniques are used in different disciplines: research, teaching, and clinical applications. This book explores the research currently being carried out at the molecular, subcellular, and cellular levels, both in normal and pathological processes, from genetic mechanisms to intra- and intercellular signaling. This book includes cutting-edge research reviews and descriptions of technological advances to modify bodily cells and tissues. Targeted at students and researchers in biological, medical, and related disciplines, this book will provide an overview of...
This book is dedicated to “learning and memory,” a concept at the heart of neuroscience. Learning is about acquiring knowledge and skills, forming memories, and how behavior changes based on past experiences. Learning is closely related to memory. Memory is about the recall and expression of what one has learned. This book presents contributions to learning and memory, ranging from molecular, cellular, anatomical, developmental, and systems to disease-oriented studies. As such, the book provides a gateway for newly interested investigators and serves as a resource for seasoned researchers of learning and memory. Targeted at students and researchers in biological, medical, and behavioral disciplines, this book offers an overview of the work that is being done in this field and highlights any gaps and areas that would benefit from further exploration. Individual chapters focus on research advances in different brain regions and experimental models. In addition, the book will contribute to the training of current and future neuroscientists.
This book discusses timely topics in the field of neurophysiology ranging from descriptions of nerve cells and glial cells to neural networks, sensory processing, neuroplasticity, neuropathophysiology, and human behavior. As such, all organizational levels of the nervous system are considered in one or more of the book’s twelve chapters. The chapters review or present novel findings and provide the reader with an overview of the current state of the art of neurophysiology research. They discuss research advances in different brain regions and experimental models. In addition, the book contributes to the training of current and future neuroscientists and, hopefully, will lead us on the path to curing some of the biggest challenges in human health.
‘Connectivity and Functional Specialization in the Brain’ is a topic that describes nerve cells in terms of their anatomical and functional connections. The term connectome refers to a comprehensive map of neural connections, like a wiring diagram of an organism’s nervous system. Connectomics, the study of connectomes, can be applied to individual neurons and their synaptic connections, as well as to connections between neuronal populations or to functional and structural connectivity of different brain regions. This book addresses neural connectivity at these various scales in health and disease. The chapters review novel findings related to neuroanatomy and cell biology, neurophysiol...
Nerve cells form thousands of contact points, the synapses, to communicate information with other neurons and target cells. Synapses are sites for changes in brain function through modification of synaptic transmission termed synaptic plasticity. The study of synaptic plasticity has flourished over the years with the advancement of technical breakthroughs and is a timely scientific endeavor today just like it was several decades ago. This book contributes to our understanding of synaptic plasticity at the molecular, biochemical, and cellular systems and behavioral level and informs the reader about its clinical relevance. The book contains ten chapters in three sections: (1) "Mechanisms of S...
Our sense of smell is of critical importance in our daily lives and it contributes to our personal wellbeing and safety as well as communication with others. However, it is only when disease or injury impairs its function that we appreciate the relevance of this sensory modality. During the past three decades, research of the olfactory sense has seen an ever-growing interest in this exciting field of study. This book provides the reader with an overview of the latest developments in sino-nasal and olfactory system disorders and focuses on the most important evidence-based developments in this area. This book addresses disorders, dysfunctions, diseases, and syndromes of the olfactory system ranging from molecular, cellular, and systems to cognitive and behavioral topics. Individual chapters center around recent advances in specific areas of chemosensory pathological conditions, while other chapters focus on technological developments to study the function and dysfunction of the olfactory pathways.
The sensory nervous system is of critical importance in our daily lives and contributes to our personal well-being and safety as well as communication with others. However, it is only when disease or injury impair its function that we fully appreciate the relevance of our sensory modalities. During the past decades, research of our senses has seen an ever-growing interest in this exciting field of study. This book provides the reader with an overview of the current state-of-the-art of research of our senses and focuses on the most important evidence-based developments in this area. This book addresses both the physiology and pathophysiology of our sensory nervous system ranging from molecular, cellular, and systems to cognitive and behavioral topics. Individual chapters focus on recent advances in specific areas of sensory systems in different model organisms and humans. All chapters represent recent contributions to the rapidly developing field of sensory science.
If one asks what neuroscience is, the answer can be found in this book. Neuroscience embraces not only anatomical and physiological studies but also cell biology, computer science, and biochemistry. Equally important for neuroscientific research are other disciplines, such as psychology, psychiatry, neurology and additional recent ones, such as neuroeconomics and social neuroscience. This book comprises chapters on diverse topics in neuroscience ranging from cellular, computational, cognitive, and clinical neuroscience. Individual chapters focus on recent advances in specific areas including social neuroscience, which is a relatively new field that studies the neural basis of social interactions. Other chapters focus on technological developments such as optical tools to study the function of the brain. All chapters represent recent contributions to the rapidly developing field of neuroscience and illustrate the range of research conducted under the umbrella of the truly interdisciplinary neurosciences.
Epigenetics, which deals with the study of heritable gene expression that takes place independent of changes in DNA sequence, and optogenetics, which deals with the study of genes expressed under the influence of light, are two emerging areas of study and research that have contributed immensely to our current knowledge of mechanisms and disease processes in humans. These disciplines are interrelated in the broader picture of biology and one can be used to change or modify the other. The complexity of the techniques involved in these disciplines often leads to a lack of proper understanding by researchers from other disciplines and the scientific community at large. As such, this book provides simple and easy-to-follow explanations of some of the most exciting areas of research in these disciplines.