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This book examines non-invasive, electrical-based methods for disease diagnosis and assessment of heart function. In particular, a formalized signal model is proposed since this offers several advantages over methods that rely on measured data alone. By using a formalized representation, the parameters of the signal model can be easily manipulated and/or modified, thus providing mechanisms that allow researchers to reproduce and control such signals. In addition, having such a formalized signal model makes it possible to develop computer tools that can be used for manipulating and understanding how signal changes result from various heart conditions, as well as for generating input signals f...
This book introduces the latest advances relating to the pathophysiology, biophysics, monitoring and treatment of traumatic brain injury, hydrocephalus, and stroke presented at the 16th International Conference on Intracranial Pressure and Neuromonitoring (the "ICP Conference"), held in Cambridge, Massachusetts, in June 2016 in conjunction with the 6th Annual Meeting of the Cerebral Autoregulation Research Network. Additionally, the conference held special sessions on neurocritical care informatics and cerebrovascular autoregulation. The peer-reviewed papers included were written by leading experts in neurosurgery, neurointensive care, anesthesiology, physiology, clinical engineering, clinical informatics and mathematics who have made important contributions in this translational area of research, and their focus ranges from the latest research findings and developments to clinical trials and experimental studies. The book continues the proud tradition of publishing key work from the ICP Conferences and is a must-read for anyone wishing to stay abreast of recent advances in the field.
An authoritative and in-depth treatment of state space methods, with a range of applications in neural and clinical data.
Scientists offer personal accounts of the challenges, struggles, successes, U-turns, and satisfactions encountered in their careers in industry, academia, and government. This insightful book offers essential life and career lessons for newly minted STEM graduates and those seeking a career change. Thirty-six leading scientists and engineers (including two Nobel Prize winners) describe the challenges, struggles, successes, satisfactions, and U-turns encountered as they established their careers. Readers learn that there are professional possibilities beyond academia, as contributors describe the paths that took them into private industry and government as well as to college and university ca...
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The main aim of Healthcare 4.0: Health Informatics and Precision Data Management is to improve the services given by the healthcare industry and to bring meaningful patient outcomes by applying the data, information and knowledge in the healthcare domain. Features: Improves the quality of health data of a patient Presents a wide range of opportunities and renewed possibilities for healthcare systems Gives a way for carefully and meticulously tracking the provenance of medical records Accelerates the process of disease-oriented data and medical data arbitration Brings meaningful patient health outcomes Eradicates delayed clinical communications Helps the research intellectuals to step down further toward the disease and clinical data storage Creates more patient-centered services The precise focus of this handbook is on the potential applications and use of data informatics in healthcare, including clinical trials, tailored ailment data, patient and ailment record characterization and health records management.
Nearly 80 short papers originating from the 14th International Symposium on Intracranial Pressure and Brain Monitoring held in Tuebingen, Germany, in September 2010 present experimental as well as clinical research data related to the naming topics of the conference. The papers have undergone a peer-reviewing and are organized in the following sections: methods of brain monitoring and data analysis, methods of invasive and non-invasive ICP assessment, the role of autoregulation, the role of tissue oxygenation and near-infrared spectroscopy, hydrocephalus/IIH imaging and diagnosis, management and therapy of hydrocephalus, management and therapy of traumatic brain injury, management and therapy of subarachnoid and intracranial hemorrhage, experimental approaches to acute brain disease. The book gives a good overview on the latest research developments in the field of ICP and related brain monitoring and on management and therapy of relevant acute brain diseases.
This volume synthesizes theoretical and practical aspects of both the mathematical and life science viewpoints needed for modeling of the cardiovascular-respiratory system specifically and physiological systems generally. Theoretical points include model design, model complexity and validation in the light of available data, as well as control theory approaches to feedback delay and Kalman filter applications to parameter identification. State of the art approaches using parameter sensitivity are discussed for enhancing model identifiability through joint analysis of model structure and data. Practical examples illustrate model development at various levels of complexity based on given physiological information. The sensitivity-based approaches for examining model identifiability are illustrated by means of specific modeling examples. The themes presented address the current problem of patient-specific model adaptation in the clinical setting, where data is typically limited.
In this book, Richardson crosses disciplinary boundaries to examine mental hygiene issues of contemporary concern in both the United States and Canada. The work juxtaposes a social history of the child in the twentieth century to shifts in private and public power as influenced by the mental hygiene movements in both countries. The author shows how the historical record sheds light on current policy concerned with mentally, emotionally, and educationally handicapped children. As a sociology of mental illness, the book examines the relationship between mental hygiene as a form of knowledge and the social institutions that fostered the use of psychiatric perspectives concerning child and family life. Significant topics covered in this regard include the history of early childhood and parent education, the origins of child psychiatry in treating juvenile delinquency, and the evolution of contemporary concepts of normal development.