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Free radicals and other reactive oxygen species are constantly formed in the human body and have been implicated in human diseases such as cancer, atherosclerosis, rheumatoid arthritis, Parkinson's disease, and malaria. This observation has raised the possibility that antioxidants could act as prophylactic agents. However, it remains to be fully established whether oxidative stress makes a significant contribution to the pathology of a given disease or whether it is an epiphenomenon. Indeed, development of specific assays applicable to humans would greatly contribute to our understanding of the role played by free radicals and their modulation by antioxidants in normal physiology and in human diseases. This book addresses the key methodological questions.
“A compelling perspective on the evolution of sports business . . . provides an excellent roadmap to maximizing the benefits and minimizing the pitfalls.” —David Stern, NBA Commissioner The businesses behind Dubai Sports City, the branding of David Beckham, and the popularity of fantasy sports leagues are unmistakable indicators that the sports and the entertainment industries are quickly becoming one and the same. This rapid convergence has been key to the sports business industry’s continued growth and financial success. Money Games not only analyzes how industry stakeholders have monetized this convergence, but also answers this core question: how can the sports business continue ...
The Video Game Industry provides a platform for the research on the video game industry to draw a coherent and informative picture of this industry. Previously this has been done sparsely through conference papers, research articles, and popular science books. Although the study of this industry is still stigmatized as frivolous and ‘only’ game oriented, those who grew up with video games are changing things, especially research agendas, the acceptance of studies, and their interpretation. This book describes and defines video games as their own special medium. They are not pinball from which they grew, nor movies which they sometimes resemble. They are a unique form of entertainment based on meaningful interactions between individuals and machine across a growing sector of the population. The Video Game Industry provides a reference foundation for individuals seriously interested in the industry at the academic level. As a result, this book will serve as a reference in curricula associated with video game development for years to come.
In recent years, urbanization and industrialization have produced large amounts of heavy metals, which are highly toxic to both humans and the environment. This book presents a comprehensive overview of heavy metals including their physiochemical properties, toxicity, transfer in the environment, legislation, environmental impacts, and mitigation measures. Written by experts in the field, chapters include scientific research as well as case studies.
With some 6,000 entries, A Bibliography of Tennessee History will prove to be an invaluable resource for anyone--students, historians, librarians, genealogists--engaged in researching Tennessee's rich and colorful past. A sequel to Sam B. Smith's invaluable 1973 work, Tennessee History: A Bibliography, this book follows a similar format and includes published books and essays, as well as many unpublished theses and dissertations, that have become available during the intervening years. The volume begins with sections on Reference, Natural History, and Native Americans. Its divisions then follow the major periods of the state's history: Before Statehood, State Development, Civil War, Late Nin...
With the dawn of the nuclear age, it has become essential to develop radiomodulators, particularly radiation countermeasure agents, for the benefit of mankind. Despite years of concerted research endeavors world-over, non-toxic and effective radiomodulators remain elusive. In recent years, there has been a new focus on herbals, which are also promising sources of radiomodulatory drugs. This book discusses the potential of radiation countermeasure agents and radiosensitizers of herbal origin, and their multifaceted mode of action, particularly in nuclear operations, rescue operations, deep space missions, and application during radiotherapy. Comprising 22 chapters written by industry, clinical and academic experts, this book will appeal to readers in radiation biology, radiation oncology, military medicine, homeland defense, traditional, holistic and modern medicine, space biology, pharmacology and toxicology.
Natural products play crucial roles in modern drug development, and constitute a prolific source of novel lead compounds or pharmacophores for ongoing drug discovery programs. Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds presents cutting-edge research in the chemistry of bioactive natural products and demonstrates how natur
Advances in Structural Adhesive Bonding, Second Edition reviews developments in adhesive bonding for a range of advanced structural engineering applications. This new edition has been fully revised to include the latest advances in materials, testing and modeling methods, lifecycle considerations, and industrial implementation. Sections review advances in commonly used groups of structural adhesives, covering epoxy, acrylic, anaerobic and cyanoacrylate, polyurethane, and silicone adhesives, along with toughening. Other chapters cover various types of adherends and pre-treatment methods for structural materials, including metals, plastics, composites, wood and joint design and testing, includ...
Wine is a widely consumed beverage due to its unique and pleasant sensory properties. Wine is composed of more than one thousand chemical compounds (e.g., alcohols, esters, acids, terpenoids, phenolic compounds, flavonoids, anthocyanins, minerals, and vitamins, among others) resulting from several chemical and biochemical processes. Microextraction techniques in tandem with high-resolution analytical instruments have been applied by wine researchers to expand the knowledge of wine’s chemical composition with the purposes of improving wine quality, supporting winemaker decisions related to the winemaking process, and guaranteeing the authenticity of wine. As a result, we proposed “Chemica...
This book provides a plethora of information about global arsenic (As) contamination and the challenges for environment. Arsenic is a naturally occurring metalloid that is widely distributed in water, soil, air and biota from natural and anthropogenic sources. Arsenic has been found in drinking water in over 100 countries worldwide, which caused a major public health issue including: cardiovascular disorders, diabetes, and cancers of various organs - these are some of the general health effects of As exposure. Exposure of plants to As, even at very low concentrations, can cause many morphological, physiological, and biochemical changes. The recent research on As in the water-soil-plant-human...