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Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R
This book focuses on the analysis of dose-response microarray data in pharmaceutical settings, the goal being to cover this important topic for early drug development experiments and to provide user-friendly R packages that can be used to analyze this data. It is intended for biostatisticians and bioinformaticians in the pharmaceutical industry, biologists, and biostatistics/bioinformatics graduate students. Part I of the book is an introduction, in which we discuss the dose-response setting and the problem of estimating normal means under order restrictions. In particular, we discuss the pooled-adjacent-violator (PAV) algorithm and isotonic regression, as well as inference under order restr...
Rethinking Cybercrime
The book provides a contemporary ‘snapshot’ of critical debate centred around cybercrime and related issues, to advance theoretical development and inform social and educational policy. It covers theoretical explanations for cybercrime, typologies of online grooming, online-trolling, hacking, and law and policy directions. This collection draws on the very best papers from 2 major international conferences on cybercrime organised by UCLAN. It is well positioned for advanced students and lecturers in Criminology, Law, Sociology, Social Policy, Computer Studies, Policing, Forensic Investigation, Public Services and Philosophy who want to understand cybercrime from different angles and perspectives.
Justice as Message
This work is the first to examine the expressive and communicative functions of law in a comprehensive way in the field of atrocity crime. It shows that expression and communication are not only inherent parts of the punitive functions of international criminal justice, but are represented in a whole spectrum of practices.
Yearbook of International Humanitarian Law, Volume 20, 2017
The main theme of this volume of the Yearbook of International Humanitarian Lawis the development and interpretation of international humanitarian law (IHL). It iselaborated upon in several chapters that examine the role of non-state armed groupsin the development and interpretation of IHL, the impact of international criminal lawon the development of IHL, the notion of external non-international armed conflicts,and the regulation of prolonged occupation under international law. The second theme of this volume is dedicated to targeting in armed conflicts. Specifictopics include precautions in attack in urban and siege warfare, the targeting of theIslamic State’s religious personnel in Iraq...
Accountability for Violations of International Humanitarian Law
International criminal adjudication, together with the prosecution and appropriate punishment of offenders at a national level, remains the most effective means of enforcing International Humanitarian Law. This book considers the various issues emanating from present-day breaches of norms of International Humanitarian Law (IHL) and the question of how impunity for such breaches can be tackled. Honouring the work of Timothy McCormack, Professor of International Law at the University of Melbourne and a world renowned expert on IHL and International Criminal Law, contributors of the book explore the interplay between the rules governing accountability for violations of IHL and other areas of la...
