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Depression: From Psychopathology to Pharmacotherapy
Despite the availability of antidepressants for over 40 years, a substantial proportion of depressed patients do not respond adequately to treatment. Failure to respond effectively to treatment contributes to physical ill-health and psychiatric morbidity, often resulting in premature death of the depressed patient. The purpose of this volume is to consider the possible reasons for the limitations of the currently available antidepressants, to examine the advances in our understanding of the psychopathology of depression and how such knowledge may assist in the discovery of new methods of treatment. Leading international experts in this field discuss the possible underlying reasons for depression and limitations of current antidepressants. Opportunities for novel therapeutic approaches to dysfunctional circadian rhythms and mood disorders as well as current status and future perspectives for optimizing antidepressant management of depression are reviewed. This publication illustrates the breadth of the latest research and is valuable reading for psychiatrists, neuroscientists and pharmacologists.
Manual on the Character and Fitness Process for Application to the Michigan State Bar
This manual is designed to assist the graduating law student to successfully apply to the State Bar of Michigan. It covers the application process, the affidavit of personal history, and the process and procedure should your application require more formal procedures. This manual is also designed to guide applicants and practitioners to prepare and present their cases succinctly and efficiently.
Help Yourself
More than 125 gut-healthy recipes, plus advice and strategies to relieve inflammation-induced symptoms such as fatigue, weight gain, mood swings, and chronic pain
Building the Modern Church
Fifty years after the Second Vatican Council, architectural historian Robert Proctor examines the transformations in British Roman Catholic church architecture that took place in the two decades surrounding this crucial event. Inspired by new thinking in theology and changing practices of worship, and by a growing acceptance of modern art and architecture, architects designed radical new forms of church building in a campaign of new buildings for new urban contexts. A focussed study of mid-twentieth century church architecture, Building the Modern Church considers how architects and clergy constructed the image and reality of the Church as an institution through its buildings. The author exa...
Metabolic Effects of Psychotropic Drugs
Major depression and bipolar disorder are chronic enduring serious mental illnesses (SMI) with devastating effects on psychosocial functioning and may culminate in suicide. Over the past years, it has become apparent that subjects with these conditions can also develop the metabolic syndrome, which is a series of obesity-related physical conditions with an endocrine basis. This book brings together reviews that help put into context exactly why subjects with SMI develop obesity, prediabetic status, overt type 2 diabetes mellitus and related cardiovascular events. The relationship between prolactin and bone mineral density in subjects under medical treatment and the underlying dopaminergic mechanisms as well as the immunological changes occurring as an integral part of SMI and their effects on endocrine function are discussed and reviewed. Psychiatrists, diabetologists, cardiologists, family practitioners, public health physicians as well as basic science researchers will find valuable guidelines when screening for type 2 diabetes mellitus and cardiovascular disease in SMI.
10 Years of Gastrointestinal and Hepatic Pharmacology
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
The Bipolar Book
As a major mainstay of clinical focus and research today, bipolar disorder affects millions of individuals across the globe with its extreme and erratic shifts of mood, thinking and behavior. Edited by a team of experts in the field, The Bipolar Book: History, Neurobiology, and Treatment is a testament and guide to diagnosing and treating this exceedingly complex, highly prevalent disease. Featuring 45 chapters from an expert team of contributors from around the world, The Bipolar Book delves deep into the origins of the disorder and how it informs clinical practice today by focusing on such topics as bipolar disorder occurring in special populations, stigmatization of the disease, the role genetics play, postmortem studies, psychotherapy, treatments and more. Designed to be the definitive reference volume for clinicians, students and researchers, Aysegül Yildiz, Pedro Ruiz and Charles Nemeroff present The Bipolar Book as a "must have" for those caregivers who routinely deal with this devastating disease.
Gut Feelings
Why the microbiome--our rich inner ecosystem of microorganisms--may hold the keys to human health. We are at the dawn of a new scientific revolution. Our understanding of how to treat and prevent diseases has been transformed by knowledge of the microbiome—the rich ecosystem of microorganisms in and on every human. These microbial hitchhikers may hold the keys to human health. In Gut Feelings, Alessio Fasano and Susie Flaherty show why we must go beyond the older, myopic view of microorganisms as our enemies to a broader understanding of the microbiome as a parallel civilization that we need to understand, respect, and engage with for the benefit of our own health. Recent advances in under...
The Enlightened Gene
Are humans inherently good? Where does compassion come from? Is death essential for life? The surprising confluence of Buddhist thought and cutting-edge biology.
