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Evolution after Gene Duplication
Gene duplication has long been believed to have played a major role in the rise of biological novelty through evolution of new function and gene expression patterns. The first book to examine gene duplication across all levels of biological organization, Evolution after Gene Duplication presents a comprehensive picture of the mechanistic process by which gene duplication may have played a role in generating biodiversity. Key Features: Explores comparative genomics, genome evolution studies and analysis of multi-gene families such as Hox, globins, olfactory receptors and MHC (immune system) A complete post-genome treatment of the topic originally covered by Ohno's 1970 classic, this volume ex...
Nanoparticles in Cancer Therapy
This book presents the role of nanoparticles in cancer therapy, emphasizing their innovative applications across treatment, diagnosis and the development of therapeutic strategies. The first section of the book describes the applications of nanoparticles in cancer vaccines and gene therapy. It features discussions on polymeric nanoparticles as nanovaccine carriers, membrane-based nano-vaccines for immunotherapy and gene therapy techniques employing nanoparticles. The second section presents advanced nanomedicine approaches, specifying the role of chemodynamic nanoparticles in cancer theranostics, the application of low-dimensional nanomaterials and emerging strategies against drug resistance...
Computational Methods in Protein Evolution
This volume presents a diverse collection of methodologies used to study various problems at the protein sequence and structure level. The chapters in this book look at issues ranging from broad concepts like protein space to specifics like antibody modeling. Topics include point mutations, gene duplication, de novo emergence of new genes, pairwise correlated mutations, ancestral protein reconstruction, homology modelling, protein stability and dynamics, and protein-protein interactions. The book also covers a wide range of computational approaches, including sequence and structure alignments, phylogenies, physics-based and mathematical approaches, machine learning, and more. Written in the ...
SOCCER WORLD 2017/2018
Considerato dagli esperti una vera è propria bibbia calcistica, SOCCER WORLD Annuario del calcio internazionale contiene una quantità di informazioni talmente vasta, da renderlo unico nel suo genere. L'edizione 2017/18 si arricchisce di nuove e utili informazioni: - Classifiche finali di oltre 80 campionati di tutto il mondo - Statistiche complete di tutte le competizioni per club e nazionali - Oltre 500 squadre da tutto il mondo con rose e disposizioni in campo - Il calciomercato come non lo avete mai visto club per club - Presenze e reti dei giocatori in nazionale scesi in campo nel 2017 - Calendari completi giornata per giornata - Albo d'oro e record di tutte le competizioni presenti nel mondo - Tutti i risultati delle qualificazioni al Mondiale di Russia 2018 Una pubblicazione fondamentale che permette di monitorare a fondo l'andamento della stagione calcistica appena iniziata
Quantum Robotics
Quantum robotics is an emerging engineering and scientific research discipline that explores the application of quantum mechanics, quantum computing, quantum algorithms, and related fields to robotics. This work broadly surveys advances in our scientific understanding and engineering of quantum mechanisms and how these developments are expected to impact the technical capability for robots to sense, plan, learn, and act in a dynamic environment. It also discusses the new technological potential that quantum approaches may unlock for sensing and control, especially for exploring and manipulating quantum-scale environments. Finally, the work surveys the state of the art in current implementations, along with their benefits and limitations, and provides a roadmap for the future.
The Autobiography of a Transgender Scientist
A leading scientist describes his life, his gender transition, his scientific work, and his advocacy for gender equality in science. Ben Barres was known for his groundbreaking scientific work and for his groundbreaking advocacy for gender equality in science. In this book, completed shortly before his death from pancreatic cancer in December 2017, Barres (born in 1954) describes a life full of remarkable accomplishments—from his childhood as a precocious math and science whiz to his experiences as a female student at MIT in the 1970s to his female-to-male transition in his forties, to his scientific work and role as teacher and mentor at Stanford. Barres recounts his early life—his inte...
Ancestral Sequence Reconstruction
Ancestral sequence reconstruction is a technique of growing importance in molecular evolutionary biology and comparative genomics. As a powerful tool for testing evolutionary and ecological hypotheses, as well as uncovering the link between sequence and molecular phenotype, there are potential applications in a range of fields.Ancestral Sequence Reconstruction starts with a historical overview of the field, before discussing the potential applications in drug discovery and the pharmaceutical industry. This is followed by a section on computational methodology, which provides a detailed discussion of the available methods for reconstructing ancestral sequences (including their advantages, dis...
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Chemistry and Biology of Non-canonical Nucleic Acids
Discover the fundamentals and intricacies of a subject at the interface of chemistry and biology with this authoritative resource Chemistry and Biology of Non-canonical Nucleic Acids delivers a comprehensive treatment of the chemistry and biology of non-canonical nucleic acids, including their history, structures, stabilities, properties, and functions. You'll learn about the role of these vital compounds in transcription, translation, regulation, telomeres, helicases, cancers, neurodegenerative diseases, therapeutic applications, nanotechnology, and more. An ideal resource for graduate students, researchers in physical, organic, analytical, and inorganic chemistry will learn about uncommon ...
