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Physiology and Pathology of Chloride Transporters and Channels in the Nervous System
The importance of chloride ions in cell physiology has not been fully recognized until recently, in spite of the fact that chloride (Cl-), together with bicarbonate, is the most abundant free anion in animal cells, and performs or determines fundamental biological functions in all tissues. For many years it was thought that Cl- was distributed in thermodynamic equilibrium across the plasma membrane of most cells. Research carried out during the last couple of decades has led to a dramatic change in this simplistic view. We now know that most animal cells, neurons included, exhibit a non-equilibrium distribution of Cl- across their plasma membranes. Over the last 10 to 15 years, with the grow...
Anion Channels and Transporters
This book provides an overview on recent progress in anion channels and transporters. It covers multiple scales of analysis ranging from studying the molecular basis of function at atomic resolution to cellular consequences to channel/transporter dysfunction and approaches to correct such processes by pharmacological intervention. Similar anion channels and transporters are expressed in multiple tissues – often fulfilling similar cellular tasks, but also clearly distinct functions. The aim is to combine work on multiple cell and organ systems.
Handbook of Graphene, Volume 2
The second volume in a series of handbooks on graphene research and applications Graphene is a valuable nanomaterial used in technology. This handbook features graphene topics related to Physics, Chemistry, and Biology. The Handbook of Graphene, Volume 2 delivers an overview on the numerous and diverse graphene research directions and innovations. The handbook covers a range of areas including graphene in optoelectronic devices and as a detector of biomolecules.
Polarons in Bulk Materials and Systems With Reduced Dimensionality
An enormous theoretical effort has been made to treat electron-phonon coupled systems, with particular emphasis on Many Body aspects for dense electron systems, taking into account continuum as well as lattice polaron effects. Treating such aspects of polaron theory has been made possible because of powerful Many Body techniques which include: Exact Diagonalization techniques, Quantum Monte Carlo approaches, Density Matrix renormalization group and Dynamical Mean Field Theory. All these advances in polaron theory needed to be accompanied by: (i) an equally important advance in material research which produced many new materials such as the high Tc cuprates, the manganites and nickelates and ...
Fluorescence Imaging and Biological Quantification
This comprehensive reference work details the latest developments in fluorescence imaging and related biological quantification. It explores the most recent techniques in this imaging technology through the utilization and incorporation of quantification analysis which makes this book unique. It also covers super resolution microscopy with the introduction of 3D imaging and high resolution fluorescence. Many of the chapter authors are world class experts in this medical imaging technology.
Protein Targeting, Transport, and Translocation
Protein Targeting, Transport, and Translocation presents an in-depth overview on the topic of protein synthesis, covering all areas of protein science, including protein targeting, secretion, folding, assembly, structure, localization, quality control, degradation, and antigen presentation. Chapters also include sections on the history of the field as well as summary panels for quick reference. Numerous color illustrations complement the presentation of material. This book is an essential reference for anyone in biochemistry and protein science, as well as an excellent textbook for advanced students in these and related fields. - Basic principles and techniques - Targeting adn sorting sequences - Protein export in bacteria - Membrane protein integration into ER and bacterial membranes - Protein translocation across the ER - Disulfide bond formation in prokaryotes and eukaryotes - Quality control in the export pathway - Import of proteins into organelles - The secretory pathway - Vesicular transport - Spectacular color throughout
The National Cyclopaedia of American Biography
Includes cumulative subject index of the entire set. 1 v.
