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How the Mistakes Were Made
Laura Loss came of age in the hardcore punk scene of the early 1980s. The jailbait bass player in her brother Anthony's band, she grew up traveling the country, playing her heart out in a tight network of show venues to crowds soaked in blood and sweat. The band became notorious, the stars of a shadow music industry. But when Laura was 18, it all fell apart. Anthony's own fans destroyed him, something which Laura never forgot. Ten years later, Laura finds her true fame with the formation of The Mistakes, a gifted rock band that bursts out of ‘90s Seattle to god-like celebrity. When she discovered Nathan and Sean, the two flannel-clad misfits who, along with her, composed the band, she inst...
One Potato
Eddie Morales finds his lowly R&D life completely upended when his Boise-based biotech firm dispatches him to Puerto Malogrado, a tiny but tumultuous country in South America where the international media is accusing their experimental potatoes of causing a bizarre medical crisis. Eddie unwillingly arrives in South America only to find his plans for a quick resolution thwarted when he gets caught between the two sides of an impending revolution, each hoping to capitalize on the potato scandal in order to seize power. Eddie stumbles into a conspiracy that reveals just how far his company will go to advance its potato empire. He is forced to make a choice: what—and who—will he sacrifice to preserve his own future in this brave new world of biotechnology? Darkly funny and compassionately rendered, One Potato charts the crooked line between nature and technology and takes a deep look into a future shaped by disasters both natural and devastatingly man-made.
Surfing's Greatest Misadventures
Surfing's Greatest Misadventures contains thirty of themost engaging, humorous and unbelievable stories ofsurfing life from the past fifty years. Culled fromhundreds of submissions, the non-fiction stories selectedfor this one-of-a-kind collection run the gamut from theterrifying to the comical to the downright bizarre. Thestories ......
Fishing's Greatest Misadventures
Fishings Greatest Misadventures presents 25 larger-than-life true stories covering the spectrum of fish tales, from terrifying to comical to downright bizarre. Everyday fishermen, journalists, and pros tell their stories of freak accidents, fish attacks, sabotage, pranks, getting lost at sea, idiotic decisions, eerie incidents, and other jaw-dropping calamities. This book takes you from the freshwater to the sea with stories about every form of angling, from fly-casting for trout to noodling for catfish, and big game sport fishing to casting for the unknown.
Translational Stroke Research
This volume sets a basis for effective translational research. Authored by experts in the field of translational stroke research, each chapter specifically addresses one or more components of preclinical stroke research. The emphasis is placed on target identification and drug development using state-of-the-art in vitro and in vivo assays, in combination with in vitro toxicology assays, AMDE and clinical design.
Peptide Receptors
Peptide Receptors Part I was published in 2000 (as volume 16 of the Handbook of Chemical Neuroanatomy series). This volume summarized current knowledge on the discrete anatomical distribution of ten families of neuropeptide receptors expressed in the mammalian CNS. Part II is its natural complement with chapters covering six additional families of neuropeptide receptors for ligands ranging from well known peptides such as the opioids and neurotensin to recently isolated ones like the orexins. As in the case of Part I, this volume integrates photomontages and maps of quantitative receptor autoradiography, in situ hybridization histochemistry and immunocytochemistry. Data derived from transgenic and knock-out animals are also summarized, helping to decipher the possible physiological and Pathophysiological role(s) of a given peptide family. Some chapters also review current knowledge on the profile of internalization of the neuropeptide-receptor complex, an area of intense research activities that should help to better understand mechanisms involved in desensitization and tachyphylaxis.
The Boston Directory
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Drug Discovery and Evaluation: Pharmacological Assays
Now expanded and updated to include molecular biology and genetic engineering techniques. The second edition of this successful reference book contains a comprehensive selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Each of the more than 1000 assays comprises a detailed protocol outlining the purpose and rationale of the method, a critical assessment of the results and their pharmacological and clinical relevance. The enclosed and fully searchable CD ROM allows easy identification of specific tests. An appendix with up-to-date guidelines and legal regulations for animal experiments in various countries will help the reader to plan experiments more effectively.
