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Gut Microbiota in Health and Disease
Gut microbiota plays a crucial role in host health maintenance and disease pathogenesis. The largest reservoir of microbiota exists in gastrointestinal tract, both in the lumen, where microbes facilitate primary and secondary metabolism, and on mucosal surfaces, where they interact with host immune cell populations. Dysbiosis is associated with decreased microbiota function and diversity, disrupted epithelial barrier, bacterial translocation, inflammation, and local/systemic microbial-driven immunomodulation. In fact, gut dysbiosis appears to be associated with increased risk of developing inflammatory, autoimmune, and malignant diseases. In addition, it is important to explore implications of microbiota variations on drug disposition, action and toxicity.
Exploring the Religions of Our World
Expands students' understanding of their own religious history and practice by examining other religions of the world. Each religion is introduced with a brief history, and explored through each religion's scripture or major writings, beliefs and practices, and sacred spaces and times.
Nowhere Somewhere
None
Between Empires
This study examines the wholesale trade in sugar from Brazil to markets in Europe. The principal market was northwestern Europe, but for much of the time between 1550 and 1630 Portugal was drawn into the conflict between Habsburg Spain and the Dutch Republic. In spite of political obstacles, the trade persisted because it was not subject to monopolies and was relatively lightly regulated and taxed. The investment structure was highly international, as Portugal and northwestern Europe exchanged communities of merchants who were mobile and inter-imperial in both their composition and organization. This conclusion challenges an imperial or mercantilist perspective of the Atlantic economy in its earliest phases.
International Handbook of Curriculum Research
Continuing its calling to define the field and where it is going, the Second Edition of this landmark handbook brings up to date its comprehensive reportage of scholarly developments and school curriculum initiatives worldwide, providing a panoramic view of the state of curriculum studies globally. Its international scope and currency and range of research and theory reflect and contribute significantly to the ongoing internationalization of curriculum studies and its growth as a field worldwide. Changes in the Second Edition: Five new or updated introductory chapters pose transnational challenges to key questions curriculum research addresses locally. Countries absent in the First Edition are represented: Chile, Colombia, Cypress, Ethiopia, Germany, Iran, Luxembourg, Nigeria, Peru, Poland, Portugal, Singapore, South Africa, Spain, and Switzerland. 39 new or updated chapters on curriculum research in 34 countries highlight curriculum research that is not widely known in North America. This handbook is an indispensable resource for prospective and practicing teachers, for curriculum studies scholars, and for education students around the world.
Time and Space
The texts presented in Proportion Harmonies and Identities (PHI) Time and Space were compiled to establish a multidisciplinary platform for presenting, interacting, and disseminating research. It also aims to foster awareness and discussion on Time and Space, focusing on different visions relevant to Architecture, Arts and Humanities, Design and Social Sciences, and its importance and benefits for the sense of identity, both individual and communal. The idea of Time and Space has been a powerful motor for development since the Western Early Modern Age. Its theoretical and practical foundations have become the working tools of scientists, philosophers, and artists, who seek strategies and policies to accelerate the development process in different contexts.
Grammar and Text
This volume brings together a collection of papers based on presentations given at the 10th and 11th Fora for Linguistic Sharing, organised by the Young Researchers Group of the Centro de Linguística da Universidade Nova de Lisboa (CLUNL) and held at Universidade NOVA de Lisboa, Portugal, on the 27th and 28th November 2015 and on the 25th November 2016, respectively. The papers are authored by young researchers in linguistics and present the results of original research in two broad areas, namely text and discourse linguistics and grammar. This volume also includes a brief history of the Forum for Linguistic Sharing written by its founders, Audria Leal, Carla Teixeira, Isabelle Simões Marques and Matilde Gonçalves; a keynote article on text linguistics by Matilde Gonçalves; and a keynote article on word formation by Maria do Céu Caetano. Given that it brings together contributions from different, yet complementary, subfields of linguistics, the book will appeal to a broad readership of linguists.
Formal Methods in Architecture and Urbanism
The book promotes the use of formal methods in the creation of new explicit languages for problem solving in architecture and urbanism. Formal methods bring advantages to human actions and involve the use of theoretically driven techniques, expressed in languages stemmed from mathematics. Formalization seeks to guarantee that solutions for daily problems are produced in a manner that ensures their greatest possible adequacy and the least test time in direct confrontation with reality. This book contributes to the progress of formalization in architectural methodologies by finding points of convergence between state of the art research on ontologies in architecture, BIM/VDC, CAD/CAM, cellular automata, GIS, parametric processes, processing and space syntax presented within the 3rd Symposium of Formal Methods in Architecture. The contents reach from millennial geometry to current shape grammars, engaging several formal approaches to architecture and urbanism, with different points of view, fields of application, grades of abstraction and formalization.
