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The Future of Health Economics
The pharmaceutical industry faces a well-documented perfect storm: on the one hand, the patent cliff; the lack of new blockbusters and, on the other, economic pressure on pricing from markets with growing expectations and shrinking budgets. In the face of such pressure, traditional health economics models no longer seem appropriate and yet what do we have to replace them? The growing focus on 'value' and 'cost effectiveness' are evidence of new emerging thinking although, even here, with the shift from medicine as cure to medicine as palliative, as a treatment for chronic illness and with the growing emphasis on preventative approaches, the landscape is complex and challenging. The Future of...
The Price of Global Health
Public debate on the rising cost of new biotechnology drug treatments has intensified over the last few years as healthcare budget pressures have mounted under a strained economy. Meanwhile, the demand for new, effective medical and drug treatments continues to rise as unhealthy lifestyles cause further increases in diabetes and cardiovascular disease. Global drug pricing is one of the most hotly debated yet least understood aspects of the pharmaceutical industry. How should drug prices be set and what does it mean for patients? Why do governments increasingly get involved, and what is its impact on the global competitive environment? How can a life-saving industry have a poorer image than g...
New Developments in Blood Transfusion Research
Although blood transfusion saves lives and reduces morbidities in many clinical diseases and conditions, it is associated with certain risks. A transfusion-related adverse event, also called transfusion reaction, is any unfavourable event occurring in a patient during or after blood transfusion. About 0.5 per cent to 3 per cent of all transfusions result in some adverse events, but the majority of them are minor reactions with no significant consequences. In general, transfusion-related adverse events are categorised as infectious and non-infectious. However, there are other classifications in the literature based on time of occurrence (i.e. acute versus delayed) or physiological mechanism (i.e. immune mediated versus non-immune mediated). A significant proportion of adverse events may occur as a result of errors in preparation, ordering or administration of blood and blood products. This book contains the latest research in this essential field which has been revolutionised in recent decades.
Stem Cell Research
Embryonic stem cells have the ability to develop into virtually any cell in the body, and may have the potential to treat medical conditions such as diabetes and Parkinson's disease. In August 2001, President Bush announced that for the first time federal funds would be used to support research on human embryonic stem cells, but funding would be limited to 'existing stem cell lines'. The National Institutes of Health (NIH) has established the Human Embryonic Stem Cell Registry which lists stem cell lines that are eligible for use in federally funded research. Although 78 cell lines are listed, 21 embryonic stem cell lines are currently available. Scientists are concerned about the quality, l...
Der Patentauslauf von Pharmazeutika als Herausforderung beim Management des Produktlebenszyklus
Christina Raasch entwickelt ein umfassendes Ordnungsschema der durch forschende pharmazeutische Anbieter einsetzbaren Patentauslaufstrategien und analysiert diese im Detail. Anschließend leitet sie die Erfolgsfaktoren der Strategieimplementierung ab und stellt sie anhand von vier Fallstudien bedeutender Patentausläufe der letzten Jahre den Erfahrungen aus der Unternehmenspraxis gegenüber.
Die französische Nationalversammlung und die Europäische Union
Markus Stanat untersucht die Institutionalisierung des parlamentarischen Gremiums für europapolitische Angelegenheiten der französischen Nationalversammlung von seiner Konstituierung 1979 bis 2002. Vor dem verfassungs- und parlamentsrechtlichen Hintergrund analysiert er die formalen Grundlagen und die konkrete Funktionsweise der Europa-Delegation. Deutlich wird hierbei das besondere Spannungsverhältnis zwischen dem restriktiv rechtlichen Rahmen und der parlamentarischen Elastizität im politischen System der V. Republik. Der Autor bietet einen Einblick in die komplexen Arbeitsstrukturen der Nationalversammlung und zeigt, dass sich trotz verfassungsrechtlicher Beschränkungen eine funktional flexible Arbeitsstruktur etabliert hat.
Diagnostics Reimbursement Compass
"This book is a must-read for experts working with in-vitro diagnostics." -Dr. Jens Grueger In-vitro diagnostics, laboratory testing plays a crucial role in medical decision-making. COVID-19 highlighted how important diagnostics can be in managing this devastating disease. Despite the pandemic, the industry is going through a transformation. Diagnostic tests are getting more complex; and personalized, digital solutions challenge the status quo. Clinical evidence requirements are increasing, and both regulators and payers scrutinize new product approvals even closer. The Diagnostics Reimbursement Compass introduces a framework to define, demonstrate and capture the value of novel diagnostics....
Introduction to Market Access for Pharmaceuticals
Market access is the fourth hurdle in the drug development process and the primary driver for global income of any new drug. Without a strategy in place for pricing, showing value for effectiveness and an understanding of the target purchasers’ needs, the drug will fail to reach its intended market value. Introduction to Market Access for Pharmaceuticals is based on an accredited course in this area, taken from the European Market Access University Diploma (EMAUD), and is affiliated with Aix Marseille University. Key Features: The first guide to market access for pharmaceuticals based on tested teaching materials Addresses both pharmaceutical and vaccine products Includes case studies and scenarios Covers market access consdierations for Western Europe, the USA, Japan and China Explains the impact the changing healthcare market will have on your product
Nikolai Demidov
At the time of his death, Stanislavsky considered Nikolai Demidov to be ‘his only student, who understands the System’. Demidov’s incredibly forward-thinking processes not only continued his teacher’s pioneering work, but also solved the problems of an actor’s creativity that Stanislavsky never conquered. This book brings together Demidov’s five volumes on actor training. Supplementary materials, including transcriptions of Demidov’s classes, and notes and correspondence from the author make this the definitive collection on one of Russian theatre’s most important figures.
