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Fertility Control
The world’s population is growing at an unsustainable rate. From a baseline ?gure of one billion in 1800, global population is predicted to exceed nine billion by 2050 and 87. 8% of this growth will be localized in less developed countries. Such uneven population growth will yield a harvest of poverty, malnutrition, disease and en- ronmental degradation that will affect us all. Amongst the complex mixture of political, social, cultural and technological changes needed to address this issue, the development of improved methods of fertility regulation will be critical. The inadequacy of current contraceptive technologies is indicated by recent data s- gesting that the contraceptive needs of ...
Spermatogenesis — Fertilization — Contraception
Investigations into the mechanisms of spennatogenesis, sperm matura tion and fertilization provide the basis of our understanding of male re productive physiology. Since in recent years molecular and cellular en docrinology has provided particularly important contributions to our knowledge, the European Workshops on Molecular and Celluar Endo crinology of the Testis, held regularly during even years since 1980, have become a prominent forum for researchers in the field to discuss recent findings and exchange new ideas. The most recent of these Testis Workshops, the 7th, was held on May 5 - 10, 1992 at Castle Elmau in the Bavarian Alps. The main lectures of this Workshops form the core of thi...
Follicular Growth Ovulation and Fertilization
Covering the subject at both the fundamental and applied levels, Follicular Growth, Ovulation and Fertilization highlights contraception, infertility management, environment, aging, and reproductive processes. Written by experts in their respective fields, the scientific contributions cover the basic aspects of reproductive biology with a special focus on fertility control and treatment of infertility. The book highlights the latest developments in reproductive biology and their connection to the emerging techniques in reproductive medicine including andrology, reproductive biology, and ovarian function.
Round Table Discussion on BIOSCIENCE ⇋ SOCIETY
To mark the occasion of the lOOth anniversary of Schering research two events took place: a) a Workshop on Bioscience ;:=: Society, which was held November 24-30, 1990 in Berlin. The goal of the workshop was: Do current and anticipated developments in bioscience require a new covenant between science and society? The results have been published as the first volume of a newly created "Schering Foundation Workshop" series* by John Wiley & Sons Ltd, Chich ester, England (D.J. Roy, E.W. Wynne, and R.W. Old, eds. (1991), Bio science ;:=: Society, Chichester: John Wiley & Sons); b) a Round Table Discussion, held on December I, 1990, where the results of the workshop were discussed by a special invited panel. The meetings were sponsored by the Senate of the City of Berlin and Schering AG, Berlin. This publication contains summary reports of the four discussion groups of the workshop presented by their moderators, and the comments of the panel at the Round Table Discussion. This is the second volume in the "Schering Foundation Workshop" series. We hope that this series will contribute to a better understanding of science and to a better recognition of its merits.
Excitatory Amino Acids and Second Messenger Systems
This book deals with the mechanisms through which glutamate, the principal excitatory neurotransmitter in the mammalian central nervous system, modifies neuronal membrane functions and intraneuronal functions. Discussed are the hypothesis that the glutamate receptor signal may be processed by archidonic acid, nitric oxide, Ca 2+ and protein kinases. A key routefor glutamate receptors in synaptic plasticity and neuronal degeneration is beeing increasingly recognized. This is one of the most important new areas of endeavor by neurobiologists. The book, written by some of the most wellknown scientists in this field, provides a comprehensive reviewof conceptual approaches along with experiments showing a link between excitation mediated by glutamate and second messenger systems.
Computer Aided Drug Design in Industrial Research
The Ernst Schering Research Foundation sponsored its 15th workshop in Berlin on October 19-21, 1994. Leading scientists from Europe and North America were invited to discuss computer-aided drug design in industrial research. Computer-aided drug design is a very exciting field and an intellec tual challenge, like playing chess. But these reasons are no longer suf ficient to justify using this method in industry, if they ever were. Fig. 1. The participants of the workshop VI Preface Therefore, when we, together with Prof. Hoyer, started to think about this workshop, our intentions quickly became clear. We were not so much interested in the very latest developments of methods or in computer-aided drug design itself - enough conferences have dealt with these topics. However, we were very interested in the usefulness and limitations of computer-aided drug design in the indu strial research process. A lot has changed in the pharmaceutical industry recently. These changes are gaining momentum, so it is the right time to think about the role of computer-aided drug design in this changing environment.
EORTC Genitourinary Group Monograph 8
Contained within this valuable working reference is a broad-based, detailed account of the diagnosis and management of human prostate cancer. Among the important issues explored are early or delayed management, radiotherapy, radical prostatectomy, or delayed treatment in locally confined disease, testicular versus total androgen supression, the role of cytotoxic drugs, and adjuvant therapy.
Benign Prostatic Hyperplasia
This book focuses on benign prostatic hyperplasia and will include chapters on the diagnosis, epidemiology, pathogenesis, neurophysiology and treatment of the disorder.
Novel Approaches to Treatment of Osteoporosis
Osteoporosis affects a growing number of the population. Current treatments are based on prevention of further bone loss after the condition is diagnosed, often because a fracture has occurred. Treatments in the future will aim at healing osteoporosis by improving bone mass and quality. This book describes novel discoveries and research which will allow bone to be restored after it has been lost.
